Mariasole Da Boit

Dr. Mariasole Da Boit

orcid

Research Focus & Metrics

Academic Career Length

15Years (2012-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
1 January 2017 in The American Journal of Clinical Nutrition
Verified
Journal Article
Open access
PDF file
MBMariasole Da Boit
Mariasole Da Boit
RSRachael Sibson
Rachael Sibson
SSSelvaraj Sivasubramaniam
Selvaraj Sivasubramaniam
JMJudith R Meakin
Judith R Meakin
CGCarolyn Greig
Carolyn Greig
SGStuart R Gray
Stuart R Gray
Background: Resistance exercise increases muscle mass and function in older adults, but responses are attenuated compared with younger people. Data s

28 June 2016 in Physiological Reports
Verified
Journal Article
Open access
PDF file
MBMariasole Da Boit
Mariasole Da Boit
RSRachael Sibson
Rachael Sibson
JMJudith R. Meakin
Judith R. Meakin
RARichard M. Aspden
Richard M. Aspden
FTFrank Thies
Frank Thies
SGStuart R Gray
Stuart R Gray
Resistance exercise training is known to be effective in increasing muscle mass in older people. Acute measurement of protein metabolism data has indicated that the magnitude of response may differ between sexes. We compared adaptive responses in muscle mass and function to 18 weeks resistance exercise training in a cohort of older (>65 years) men and women. Resistance exercise training improved knee extensor maximal torque, 4 m walk time, time to complete five chair rises, muscle anatomical cross‐sectional area (ACSA) and muscle quality with no effect on muscle fat/water ratio or plasma glucose, insulin, triacylglycerol, IL‐6, and TNF‐ α . Differences between sexes were observed for knee extensor maximal torque and muscle quality with greater increases observed in men versus women ( P < 0.05). Maximal torque increased by 15.8 ± 10.6% in women and 41.7 ± 25.5% in men, whereas muscle quality increased by 8.8 ± 17.5% in women and by 33.7 ± 25.6% in men. In conclusion, this study has demonstrated a difference in the magnitude of adaptation, of some of the outcome measures employed, in response to 18 weeks of resistance exercise training between men and women. The mechanisms underlying this observation remain to be established.

1 January 2017 in Metabolism
Verified
Journal Article
Open access
MBMariasole Da Boit
Mariasole Da Boit
Angus HunterAngus Hunter
Angus Hunter
SGStuart R. Gray
Stuart R. Gray
N-3 PUFA (n-3) polyunsaturated fatty acids (PUFA) are a family of fatty acids mainly found in oily fish and fish oil supplements. The effects of n-3 PUFA on health are mainly derived from its anti-inflammatory proprieties and its influence on immune function. Lately an increased interest in n-3 PUFA supplementation has reached the world of sport nutrition, where the majority of athletes rely on nutrition strategies to improve their training and performance. A vast amount of attention is paid in increasing metabolic capacity, delaying the onset of fatigue, and improving muscle hypertrophy and neuromuscular function. Nutritional strategies are also frequently considered for enhancing recovery, improving immune function and decreasing oxidative stress. The current review of the literature shows that data regarding the effects of n-3PUFA supplementation are conflicting and we conclude that there is, therefore, not enough evidence supporting a beneficial role on the aforementioned aspects of exercise performance.

7 October 2019 in Nutrients
Verified
Journal Article
Open access
PDF file
DKDaniel Kashi
Daniel Kashi
ASAkbar Shabir
Akbar Shabir
MBMariasole Da Boit
Mariasole Da Boit
SBStephen Bailey
Stephen Bailey
MHMatt Higgins
Matt Higgins
Polyphenols are secondary metabolites involved in a myriad of critical processes in plants. Over recent decades, special attention has been paid to the anti-oxidative role of fruit-derived polyphenols in the human diet, with evidence supporting the contribution of polyphenols in the prevention of numerous non-communicable disease outcomes. However, due to the low concentration in biological fluids in vivo, the antioxidant properties of polyphenols seem to be related to an enhanced endogenous antioxidant capacity induced via signaling through the nuclear respiratory factor 2 pathway. Polyphenols also seem to possess anti-inflammatory and antioxidant properties and have been shown to enhance vascular function via nitric oxide mediated mechanisms. Consequently, there is rationale to support fruit-derived polyphenol supplementation to enhance exercise performance, possibly via improved muscle perfusion. Fruit-derived polyphenol supplementation in exercise studies have included a variety of fruits, e.g., New Zealand blackcurrant, pomegranate, and cherry, in the form of extracts (multicomponent or purified), juices and infusions to varying degrees of benefit. For example, research has yet to link the health-related benefits of black elderberry (Sambucus nigra L.) ingestion to exercise performance in spite of the purported health benefits associated with black elderberry provision in vitro and in vivo models, which has been attributed to their high antioxidant capacity and polyphenol content. This review summarizes the existing evidence supporting a beneficial effect of fruit-derived polyphenols on various biological processes and outlines the potential for black elderberry ingestion to improve nitric oxide production, exercise performance, and the associated physiological responses before-, during- and post-exercise.

1 November 2012 in Journal of Strength & Conditioning Research
Verified
Journal Article
Closed access
RMRocco Di Michele
Rocco Di Michele
Giorgio GattaGiorgio Gatta
Giorgio Gatta
ALAntonino Di Leo
Antonino Di Leo
Matteo CortesiMatteo Cortesi
Matteo Cortesi
FAFrancesca Andina
Francesca Andina
FMFranco Merni
Franco Merni
Een the anaerobic threshold (AT) as determined from the analysis of blood lactate concentration ([La]) and from a new method based on the heart rate (HR) variability (HRV). Fourteen high-level swimmers completed an incremental 7 × 200-m front crawl test, during which the HRV was measured continuously and [La] was collected after each step. To individuate the AT, the trends of the high-frequency HRV spectral power (HFPOW) and of the fraction of HFPOW relative to the respiratory sinus arrhythmia (HFPOW-RSA) were analyzed. In all the subjects, an abrupt increase of both HFPOW and HFPOW-RSA was observed and associated with the AT. The AT parameters determined, respectively, from [La] and HFPOW-RSA were similar (p > 0.05) and highly correlated (HR: 182.0 ± 8.1 vs. 181.1 ± 8.2 b·min−1, r = 0.93, 95% limits of agreement [LoA]: −6.7 to 4.9 b·min−1; velocity: 1.47 ± 0.11 vs. 1.47 ± 0.11 m·s−1, r = 0.98, 95% LoA: −0.05 to 0.05 m·s−1). Instead, the AT HR and velocity obtained from HFPOW (179.2 ± 8.4 b·min−1; 1.45 ± 0.11 m·s−1) were correlated to the corresponding parameters determined from [La] (HR: r = 0.84; velocity: r = 0.94) but underestimated them slightly (95% LoA: −11.9 to 6.3 b·min−1 and −0.11 to 0.05 m·s−1). These results demonstrate that the AT can be assessed from the HRV in swimming, providing an important testing tool for coaches. Furthermore, using the actual respiratory spectral component, rather than the total HF spectral power, allows us to obtain a more accurate estimate of AT parameters....

3 August 2021 in Molecular Nutrition & Food Research
Verified
Journal Article
Closed access
PDF file
JFJoseph Festa
Joseph Festa
MBMariasole Da Boit
Mariasole Da Boit
AHAamir Hussain
Aamir Hussain
HSHarprit Singh
Harprit Singh