Lawrence Lash is a Professor of Pharmacology at Wayne State University School of Medicine in Detroit, MI, USA. His research interests have primarily focused on roles of drug metabolism and transport and oxidative processes in the response of the kidneys to exposures to environmental toxicants and drugs whose therapeutic efficacy is dose-limited by nephrotoxicity. Major research contributions have included defining processes of plasma membrane and mitochondrial transport for GSH in kidney, defining mechanisms of metabolism and renal injury from trichloroethylene and related environmental pollutants, and developing primary human cell culture models for use in mechanistic toxicology studies.
Lawrence Lash is a Professor of Pharmacology at Wayne State University School of Medicine in Detroit, MI, USA. His research interests have primarily focused on roles of drug metabolism and transport and oxidative processes in the response of the kidneys to exposures to environmental toxicants and drugs whose therapeutic efficacy is dose-limited by nephrotoxicity. Major research contributions have included defining processes of plasma membrane and mitochondrial transport for GSH in kidney, defining mechanisms of metabolism and renal injury from trichloroethylene and related environmental pollutants, and developing primary human cell culture models for use in mechanistic toxicology studies.