The group focuses on the study of the endothelium in the context of physiology and pathology, with a focus on cancer development and progression. We investigate the endothelium as a component of the hematopoietic cell niche, which regulates stem cell maintenance and hematopoiesis. We investigate the endothelium in the context of the cancer cell niche, which contributes to cancer evolution. Malignancies associated with EBV and/or KSHV infection are of particular interest as these herpes viruses can infect endothelial cells contributing to tumor development.
Research Keywords & Expertise
Cancer Cell Biology
Vascular Biology
herpesviruses
viral diseases
Hematology Oncology
Short Biography
The group focuses on the study of the endothelium in the context of physiology and pathology, with a focus on cancer development and progression. We investigate the endothelium as a component of the hematopoietic cell niche, which regulates stem cell maintenance and hematopoiesis. We investigate the endothelium in the context of the cancer cell niche, which contributes to cancer evolution. Malignancies associated with EBV and/or KSHV infection are of particular interest as these herpes viruses can infect endothelial cells contributing to tumor development.
Honors and Awards
American Society for Clinical Investigation-Elected
Recognizes excellence in translational research
American Society for Clinical Investigation
Senior Investigator
Tenured Investigator, NIH
National Institutes of Health
NCI/CCR Intramural Research Award
Contribution of bone marrow-derived endothelial cells to cancer growth
National Cancer Institute, Center for Cancer Research
Well done!
