Removing heavy metal ions from industrial wastewater is one of the most important and difficult areas of the water treatment industry. In this study, Bacterial Cellulose/Polyvinyl Alcohol/Graphene Oxide/Attapulgite (BC/PVA/GO/APT) composites were successfully prepared via a repeated freeze-thaw method using bacterial cellulose, polyvinyl alcohol as the skeleton, and graphene oxide, attapulgite as fillers. The capacities of adsorbing Cu²⁺ and Pb²⁺ ions in solution were investigated. FTIR, XRD, SEM, BET, and TG-DSC analyses showed that the BC/PVA/GO/APT hydrogel has a better hydrophilicity, a larger specific surface area and a better thermal stability than traditional materials. We found that the adsorption of Cu²⁺ and Pb²⁺ ions can be accurately predicted by the Freundlich kinetic model, and the optimal adsorption capacities of these ions were found to be 150.79 mg/g and 217.8 mg/g respectively. Thermodynamic results showed that the adsorption process is spontaneous and exothermic. BC/PVA/GO/APT composites are suggested to be an ideal adsorption material for removing heavy metal ions from industrial wastewater.

High-altitude pulmonary edema (HAPE) is a life-threatening disease occurs in hypobaric hypoxia (HH) environment, which could be treated by Dexamethasone, but might cause side-effects. Potentilla anserina L polysaccharide (PAP) holds promising physiological and pharmacological properties which could be beneficial for HAPE treatment. In our study, the anti-hypoxia effect of PAP was firstly investigated through anti-normobaric hypoxia test and anti-acute hypoxia test. Then we established a model of HAPE and measured the lung water content, pathological changes and MDA, NO, SOD, GSH concentrations in lung tissues. We also evaluated the protein and mRNA levels of pro-inflammatory cytokines (IL-1β, IL-6, TNF-α, VEGF, NF-κB and HIF-1α) by ELISA kits, RT-PCR and Western blotting. As expected, PAP could dramatically reduce the lung water content, alleviate lung tissue injury, and inhibit MDA and NO production, it also promote SOD activity and GSH expression. In addition, it has been found that PAP blocked the NF-κB and HIF-1α signaling pathway activation, inhibited the generation of downstream pro-inflammatory cytokines. Therefore, PAP provides great potential in HAPE treatment mainly through suppression of oxidative stress and inflammatory suppression.