This page has only limited features, please log in for full access.

Unclaimed
Neha Sharma
Department of Botanical and Environmental Sciences, Guru Nanak Dev University, Amritsar 143005, India.

Basic Info

Basic Info is private.

Honors and Awards

The user has no records in this section


Career Timeline

The user has no records in this section.


Short Biography

The user biography is not available.
Following
Followers
Co Authors
The list of users this user is following is empty.
Following: 0 users

Feed

Journal article
Published: 17 October 2019 in Antioxidants
Reads 0
Downloads 0

Plants have been the basis of traditional medicine since the dawn of civilizations. Different plant parts possess various phytochemicals, playing important roles in preventing and curing diseases. Scientists, through extensive experimental studies, are playing an important part in establishing the use of phytochemicals in medicine. However, there are still a large number of medicinal plants which need to be studied for their phytochemical profile. In this study, the objective was to isolate phytochemicals from bark of Bauhinia variegata L. and to study them for their antioxidant and cytotoxic activities. The bark was extracted with methanol, followed by column chromatography and thus isolating kaempferol, stigmasterol, protocatechuic acid-methyl ester (PCA-ME) and protocatechuic acid (PCA). 2,2-azinobis-3-ethyl-benzothiazoline-6-sulfonic acid (ABTS) and 2, 2’-diphenyl-1-picrylhydrazyl radical (DPPH) radical scavenging assays were utilized for assessment of antioxidant activity, and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) dye reduction assay was used to determine cytotoxic activity against C-6 glioma rat brain, MCF-7 breast cancer, and HCT-15 colon cancer cell lines. The compounds were found to have significant antioxidant and cytotoxic activity. Since there is a considerable increase in characterizing novel chemical compounds from plant parts, the present study might be helpful for chemotaxonomic determinations, for understanding of medicinal properties as well as for the quality assessment of herbal supplements containing B. variegata bark, thus establishing its use in traditional medicine.

ACS Style

Neha Sharma; Anket Sharma; Gaurav Bhatia; Marco Landi; Marian Brestic; Bikram Singh; Jatinder Singh; Satwinderjeet Kaur; Renu Bhardwaj. Isolation of Phytochemicals from Bauhinia variegata L. Bark and Their In Vitro Antioxidant and Cytotoxic Potential. Antioxidants 2019, 8, 492 .

AMA Style

Neha Sharma, Anket Sharma, Gaurav Bhatia, Marco Landi, Marian Brestic, Bikram Singh, Jatinder Singh, Satwinderjeet Kaur, Renu Bhardwaj. Isolation of Phytochemicals from Bauhinia variegata L. Bark and Their In Vitro Antioxidant and Cytotoxic Potential. Antioxidants. 2019; 8 (10):492.

Chicago/Turabian Style

Neha Sharma; Anket Sharma; Gaurav Bhatia; Marco Landi; Marian Brestic; Bikram Singh; Jatinder Singh; Satwinderjeet Kaur; Renu Bhardwaj. 2019. "Isolation of Phytochemicals from Bauhinia variegata L. Bark and Their In Vitro Antioxidant and Cytotoxic Potential." Antioxidants 8, no. 10: 492.