Image reconstruction from undersampled k-space data has been playing an important role in fast magnetic resonance imaging (MRI). Recently, deep learning has demonstrated tremendous success in various fields and also shown potential in significantly accelerating MRI reconstruction with fewer measurements. This article provides an overview of deep-learning-based image reconstruction methods for MRI. Two types of deep-learningbased approaches are reviewed, those that are based on unrolled algorithms and those that are not, and the main structures of both are explained. Several signal processing issues for maximizing the potential of deep reconstruction in fast MRI are discussed, which may facilitate further development of the networks and performance analysis from a theoretical point of view.

Both parallel MRI and compressed sensing (CS) are emerging techniques to accelerate conventional MRI by reducing the number of acquired data. The combination of parallel MRI and CS for further acceleration is of great interest. In this paper, we propose a novel method to combine sensitivity encoding (SENSE), one of the standard methods for parallel MRI, and compressed sensing for rapid MR imaging (SparseMRI), a recently proposed method for applying CS in MR imaging with Cartesian trajectories. The proposed method, named CS‐SENSE, sequentially reconstructs a set of aliased reduced‐field‐of‐view images in each channel using SparseMRI and then reconstructs the final image from the aliased images using Cartesian SENSE. The results from simulations and phantom and in vivo experiments demonstrate that CS‐SENSE can achieve a reduction factor higher than those achieved by SparseMRI and SENSE individually and outperform the existing method that combines parallel MRI and CS. Magn Reson Med, 2009.

Diffusion models with continuous stochastic differential equations (SDEs) have shown superior performances in image generation. It can serve as a deep generative prior to solving the inverse problem in magnetic resonance (MR) reconstruction. However, low-frequency regions of k-space data are typically fully sampled in fast MR imaging, while existing diffusion models are performed throughout the entire image or k-space, inevitably introducing uncertainty in the reconstruction of low-frequency regions. Additionally, existing diffusion models often demand substantial iterations to converge, resulting in time-consuming reconstructions. To address these challenges, we propose a novel SDE tailored specifically for MR reconstruction with the diffusion process in high-frequency space (referred to as HFS-SDE). This approach ensures determinism in the fully sampled low-frequency regions and accelerates the sampling procedure of reverse diffusion. Experiments conducted on the publicly available fastMRI dataset demonstrate that the proposed HFS-SDE method outperforms traditional parallel imaging methods, supervised deep learning, and existing diffusion models in terms of reconstruction accuracy and stability. The fast convergence properties are also confirmed through theoretical and experimental validation. Our code and weights are available at https://github.com/Aboriginer/HFS-SDE.

When using paired MRI and RNA sequencing, radiomic phenotypes predictive of overall survival in glioblastoma were associated with distinct pathways involved in immune regulation, tumor proliferatio... Background The biologic meaning of prognostic radiomics phenotypes remains poorly understood, hampered in part by lack of multicenter reproducible evidence. Purpose To uncover the biologic meaning ...