Green nanotechnology incorporates the principles of green chemistry and green engineering to fabricate innocuous and eco-friendly nanoassemblies to combat the problems affecting the human health or environment. Subsequently, amalgamation of green nanotechnology with drug delivery area has actually commenced a new realm of “green nanomedicine”. The burgeoning demand for green nanotechnology-driven drug delivery systems has led to the development of different types of delivery devices, like inorganic (metallic) nanoparticles, quantum dots, organic polymeric nanoparticles, mesoporous silica nanoparticles, dendrimers, nanostructured lipid carriers, solid lipid nanoparticles, etc. The present article deals with a brief account of delivery devices produced from green methods and describes site-specific drug delivery systems (including their pros and cons) and their relevance in the field of green nanomedicine.

In the last decade, the whole scientific community has witnessed great advances and progress in the various fields of nanoscience. Among the different nanomaterials, zirconia nanomaterials have found numerous applications as nanocatalysts, nanosensors, adsorbents, etc. Additionally, their exceptional biomedical applications in dentistry and drug delivery, and interesting biological properties, viz. anti-microbial, antioxidant, and anti-cancer activity, have further motivated the researchers to explore their physico-chemical properties using different synthetic pathways. With such an interest in zirconia-based nanomaterials, the present review focuses systematically on different synthesis approaches and their impact on the structure, size, shape, and morphology of these nanomaterials. Broadly, there are two approaches, viz., chemical synthesis which includes hydrothermal, solvothermal, sol–gel, microwave, solution combustion, and co-precipitation methods, and a greener approach which employs bacteria, fungus, and plant parts for the preparation of zirconia nanoparticles. In this review article, the aforementioned methods have been critically analyzed for obtaining specific phases and shapes. The review also incorporates a detailed survey of the applications of zirconia-based nanomaterials. Furthermore, the influence of specific phases, morphology, and the comparison with their counterpart composites for different applications have also been included. Finally, the concluding remarks, prospects and possible scope are given in the last section.

This paper reports the synthesis of TiO₂ quantum dots, carbon dots (C-dots), and TiO₂/C-dots using facile sol–gel and hydrothermal methods.