An extensive amount of information is currently available to clinical specialists, ranging from details ofclinical symptoms to various types of biochemical data and outputs of imaging devices. Each type of dataprovides information that must be evaluated and assigned to a particular pathology during the diagnosticprocess. To streamline the diagnostic process in daily routine and avoid misdiagnosis, artificial intelligencemethods (especially computer aided diagnosis and artificial neural networks) can be employed. Theseadaptive learning algorithms can handle diverse types of medical data and integrate them into categorizedoutputs. In this paper, we briefly review and discuss the philosophy, capabilities, and limitations of artificialneural networks in medical diagnosis through selected examples
Nanotechnology is a rapidly growing science of producing and utilizing nano-sized particles that measure in nanometers. These nanomaterials are already having an impact on health care. Now-a-days we are using nanoproducts in various fields. Of...
Nano-technology has entered the field of medicine in recent decades and many of the nanomaterials developed have already had a high impact on health care. Among nanomaterials, gold nanoparticles (GNPs) and gold quantum dots (QDs) are receiving...
27 August 2009 in Rapid Communications in Mass Spectrometry
The applications of gas plasma and plasma modified materials in the emerging fields of medicine such as dentistry, drug delivery, and tissue engineering are reviewed. Plasma sterilization of both living and non-living objects is safe, fast and...
Copper is an endogenous metal ion that has been studied to prepare a new antitumoral agent with less side-effects. Copper is involved as a cofactor in several enzymes, in ROS production, in the promotion of tumor progression, metastasis, and angiogenesis, and has been found at high levels in serum and tissues of several types of human cancers. Under these circumstances, two strategies are commonly followed in the development of novel anticancer Copper-based drugs: the sequestration of free Copper ions and the synthesis of Copper complexes that trigger cell death. The latter strategy has been followed in the last 40 years and many reviews have covered the anticancer properties of a broad spectrum of Copper complexes, showing that the activity of these compounds is often multi factored. In this work, we would like to focus on the anticancer properties of mixed Cu(II) complexes bearing substituted or unsubstituted 1,10-phenanthroline based ligands and different classes of inorganic and organic auxiliary ligands. For each metal complex, information regarding the tested cell lines and the mechanistic studies will be reported and discussed. The exerted action mechanisms were presented according to the auxiliary ligand/s, the metallic centers, and the increasing complexity of the compound structures.