Summary: The depressurization method for natural gas hydrate exploitation encounters the difficulties of low productivity and sand production. Enhancing hydrate production efficiency and reducing massive sand production are the key issues to be solved in hydrate development. This paper proposes a new approach to hydrate reservoir stimulation and sand control by liquid-solid phase change proppant (LSP) filled in radial well (SCRP). A multicomponent flow model of sand-water-gas-hydrate is established and applied to evaluate the effect of SCRP on hydrate development. The results obtained show that the application of SCRP realizes an integrative effect of both reservoir stimulation and sand control. Radial wells increase the sweep area of pressure drop and promote hydrate decomposition. Solid particles, which are formed by LSP, not only fill and support radial wells but also act as sand control medium, preventing sand from flowing into the production well. It is found that reducing the production pressure difference can effectively reduce sand production. To achieve a large-scale stimulated reservoir volume, it is necessary to increase the length of a single radial well, the number of radial wells in the same layer, and the number of radial well layers. The spiral layout of radial wells has a better effect on improving gas production. A single radial well achieves good sand control effect with the application of the LSP system, but an increase in radial well number leads to an increase in sand production, resulting in massive amounts of sand gathered in the production well. As a result, in the case of multiple radial wells, other sand control technologies, such as mechanical sand screening, should be used along with SCRP to further reduce sand production.