1. Second Department of Internal Medicine, St. Anne´s University Hospital in Brno and Faculty of Medicine, Masaryk University, Pekařská 53, 65691 Brno, Czech Republic
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Dr. Jan Novak
1. Second Department of Internal Medicine, St. Anne´s University Hospital in Brno and Faculty of Medicine, Masaryk University, Pekařská 53, 65691 Brno, Czech Republic
MicroRNAs (miRs) are small non-coding RNAs that negatively regulate gene expression by binding to the 3` untranslated regions (3`UTR) of their target mRNAs. MiRs were shown to play pivotal roles in tissue development and function and are also involved in the pathogenesis of various diseases including cancer.