Gerhard Rammes

Dr. Gerhard Rammes

Department of Anaesthesiology and Intensive Care Medicine, Technical University Munich, Ismaningerstr. 22, 81675 Munich, Germany
orcid

Research Focus & Metrics

Academic Career Length

20Years (2007-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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11 October 2023 in Neuropharmacology
Verified
Journal Article
Open access
PTParisa Karimi Tari
Parisa Karimi Tari
CPChris G. Parsons
Chris G. Parsons
GCGraham L. Collingridge
Graham L. Collingridge
GRGerhard Rammes
Gerhard Rammes
The great potential for NMDA receptor modulators as druggable targets in neurodegenerative disorders has been met with limited success. Considered one of the rare exceptions, memantine has consistently demonstrated restorative and prophylactic properties in many AD models. In clinical trials memantine slows the decline in cognitive performance associated with AD. Here, we provide an overview of the basic properties including pharmacological targets, toxicology and cellular effects of memantine. Evidence demonstrating reductions in molecular, physiological and behavioural indices of AD-like impairments associated with memantine treatment are also discussed. This represents both an extension and homage to Dr. Chris Parson's considerable contributions to our fundamental understanding of a success story in the AD treatment landscape.

1 April 2019 in Neurobiology of Disease
Verified
Journal Article
Closed access
DRDaniel Ryskamp
Daniel Ryskamp
LWLili Wu
Lili Wu
JWJun Wu
Jun Wu
DKDabin Kim
Dabin Kim
GRGerhard Rammes
Gerhard Rammes
IBIlya Bezprozvanny
Ilya Bezprozvanny

24 July 2018 in Angewandte Chemie International Edition
Verified
Journal Article
Closed access
PDF file
ASAnna Spanopoulou
Anna Spanopoulou
LHLuzia Heidrich
Luzia Heidrich
HCHong‐Ru Chen
Hong‐Ru Chen
CFChristina Frost
Christina Frost
DHDean Hrle
Dean Hrle
AKAphrodite Kapurniotu
Aphrodite Kapurniotu

1 September 2017 in Neuropharmacology
Verified
Journal Article
Closed access
GRGerhard Rammes
Gerhard Rammes
CMCorinna Mattusch
Corinna Mattusch
MWMatthias Wulff
Matthias Wulff
FSFranziska Seeser
Franziska Seeser
MKMatthias Kreuzer
Matthias Kreuzer
CPChris G. Parsons
Chris G. Parsons

27 December 2022 in European Archives of Psychiatry and Clinical Neuroscience
Verified
Journal Article
Closed access
PDF file
RRRainer Rupprecht
Rainer Rupprecht
APArpit Kumar Pradhan
Arpit Kumar Pradhan
MKMarco Kufner
Marco Kufner
LBLisa Marie Brunner
Lisa Marie Brunner
CNCaroline Nothdurfter
Caroline Nothdurfter
GRGerhard Rammes
Gerhard Rammes

1 September 2018 in Neuropharmacology
Verified
Journal Article
Closed access
GRGerhard Rammes
Gerhard Rammes
FSFranziska Seeser
Franziska Seeser
KMKorinna Mattusch
Korinna Mattusch
KZKaichuan Zhu
Kaichuan Zhu
LHLaura Haas
Laura Haas
CPChris G. Parsons
Chris G. Parsons