Dr. Teodoro Bottiglieri works at the Center of Metabolomics, Institute of Metabolic Disease, Baylor Scott & White Health. His research over the last 30 years has focused on inherited or inborn errors of metabolism, particularly in folate, homocysteine, one-carbon metabolism, and methylation in diverse areas including vascular disease, renal insufficiency, cancer, and neurodegenerative diseases. This has led to numerous collaborations with investigators involving epidemiological studies and clinical trials, in which metabolomic analysis is required. He has a specific interest in understanding the effect of altered metabolism, induced by dietary intake, drug effects, or inherited genetic defects, on the central nervous system.