Carbon capture and storage has gained increased attention during the last decade, and several full-scale projects are currently being planned. From economic and public acceptance point of view it is important to ensure that the transportation system is operated in a safe manner, avoiding threats such as corrosion or formation of solid matters. Thus, routine chemical analyses are required to ensure that the CO₂ stream complies with the required specifications. The CO₂ will usually be transported in the liquid or supercritical state (high pressure), which makes the practicalities around chemical analyses difficult. Phase transition from liquid or supercritical state to gaseous state may also introduce several physiochemical effects that may affect the analyses. This paper discusses technical and practical challenges with CO₂ stream analyses experienced in a joint industry project that studied corrosion and chemical reactions in a simulated CO₂ transport system.