Implantable medical devices (IMDs) enable patients to monitor their health anytime and receive treatment anywhere. However, due to the limited capacity of a battery, their functionalities are restricted, and the devices may not achieve their intended potential fully. The most promising way to solve this limited capacity problem is wireless power transfer (WPT) technology. In this study, a WPT based implantable electrocardiogram (ECG) monitoring device that continuously records ECG data has been proposed, and its effectiveness is verified through an animal experiment using a rat model. Our proposed device is designed to be of size 24 × 27 × 8 mm, and it is small enough to be implanted in the rat. The device transmits data continuously using a low power Bluetooth Low Energy (BLE) communication technology. To charge the battery wirelessly, transmitting (Tx) and receiving (Rx) antennas were designed and fabricated. The animal experiment results clearly showed that our WPT system enables the device to monitor the ECG of a heart in various conditions continuously, while transmitting all ECG data in real-time.
Wireless power transfer systems are increasingly used as a means of charging implantable medical devices. However, the heat or thermal radiation from the wireless power transfer system can be harmful to biological tissue. In this research, we designed and implemented a wireless power transfer system-based implantable medical device with low thermal radiation, achieving 44.5% coil-to-coil efficiency. To suppress thermal radiation from the transmitting coil during charging, we minimized the ESR value of the transmitting coil. To increase power transfer efficiency, a ferrite film was applied on the receiving part. Based on analyses, we fabricated a cardiac monitoring system with dimensions of 17 × 24 × 8 mm3 and implanted it in a rat. We confirmed that the temperature of the wireless charging device increased by only 2 °C during the 70 min charging, which makes it safe enough to use as an implantable medical device charging system.
For the first time, under the actual three‐phase 765 kV power transmission lines, electric field energy is harvested and Zigbee‐based sensor node powered by the harvested energy is operated autonomously. A conductor tube is placed between power lines and the earth surface for electric field energy harvesting. The voltage difference between conductor tube and the earth surface is rectified and the harvested electric energy is stored in a storage capacitor. A self‐sustaining power management circuit adopting low‐power comparator with hysteresis is devised to monitor the stored energy and to operate the sensor node autonomously according to the stored energy. Experimental results under the actual three‐phase 765 kV power lines show that the data transfer period is almost inversely proportional to the square of the height of the sensor module from the earth surface. The temperature data is transmitted in every 25 s when the conductor tube is located at 4 m from the earth surface. Since the presented non‐contact energy harvesting apparatus is very simple, robust and low‐cost, it is believed that the presented technology can be widely applied to power transmission, distribution and smart grid system.
3 October 2024 in Computers in Biology and Medicine
This study presents the synthesis and characterization of hexadecyl-modified SiO2 (HD-SiO2) nanoparticles and their application in the fabrication of a multilayered elastomer hybrid sheet to enhance water resistance in implantable biomedical devices. The surface modification of SiO2 nanoparticles was confirmed via FT-IR and TGA analyses, showing the successful grafting of hydrophobic hexadecyl groups. FE-SEM and DLS analyses revealed spherical HD-SiO2 nanoparticles with an average size of 360 nm. A multilayered elastomer hybrid sheet, consisting of a PDMS-based circuit-protecting body, a water resistance layer of HD-SiO2, a planarization layer, and a biocompatible layer of polydopamine, was fabricated and characterized. The water resistance layer exhibited superhydrophobic properties, with a water contact angle of 154.7° and a 27% reduction in water vapor transmission rate (WVTR) compared to the circuit-protecting body alone. The device packaged with both the circuit-protecting body and water resistance layer demonstrated a tenfold increase in operational lifespan in water medium compared to the device without the water resistance layer. Cytotoxicity and cell proliferation tests on human dermal fibroblast cells (HDFn) confirmed the biocompatibility of the multilayered sheet, with no significant cytotoxicity observed over 48 h.