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Dr. Edson Holanda Teixeira
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Academic Career Length
28Years (1999-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications1 August 2012 in Peptides
Journal Article
BSBruno Rocha da Silva
Bruno Rocha da SilvaVFVictor Aragão Abreu Freitas
Victor Aragão Abreu FreitasLNLuiz Gonzaga Nascimento-Neto
Luiz Gonzaga Nascimento-Neto
Victor Alves CarneiroFAFrancisco Vassiliepe Sousa Arruda
Francisco Vassiliepe Sousa Arruda
ETEdson Holanda Teixeira
Edson Holanda Teixeira +2
Journal Article
Victor Alves Carneiro
Helcio Silva Dos SantosFAFancisco Vassiliepe Sousa Arruda
Fancisco Vassiliepe Sousa ArrudaPBPaulo Nogueira Bandeira
Paulo Nogueira BandeiraMAMaria Rose Jane Ribeiro Albuquerque
Maria Rose Jane Ribeiro AlbuquerqueETEdson Holanda Teixeira
Edson Holanda Teixeira +3
Croton nepetaefolius is a native plant from northeastern Brazil that belongs to the Euphorbiaceae family. The biological action of this plant has been extensively explored, being the secondary metabolites responsible for its properties alkaloids, diterpenes, and triterpenes. This study aimed to evaluate the ability of casbane diterpene (CD), isolated from the ethanolic extract of C. nepetaefolius, to inhibit microbial growth and biofilm formation of several clinical relevant species (bacteria and yeasts). It was found that CD possessed biocidal and biostatic activity against the majority of the species screened, with minimal active concentrations ranging between 125 and 500 µg/mL. In addition, it was observed that biofilm formation was inhibited even when the planktonic growth was not significantly affected. In conclusion, CD showed potential to be a natural tool for the treatment of diseases caused by different infectious microorganisms.
1 February 2018 in International Journal of Biological Macromolecules
Journal Article
RCRenata Pinheiro Chaves
Renata Pinheiro ChavesSSSuzete Roberta da Silva
Suzete Roberta da SilvaLNLuiz Gonzaga Nascimento Neto
Luiz Gonzaga Nascimento Neto
Rômulo Farias CarneiroASAndré Luis Coelho da Silva
André Luis Coelho da Silva
CNCelso Shiniti Nagano
Celso Shiniti Nagano +5
1 January 1999 in Mediators of Inflammation
Journal Article
NAN. M. N. Alencar
N. M. N. Alencar
ETEdson Holanda Teixeira
Edson Holanda TeixeiraAAA. M. S. Assreuy
A. M. S. Assreuy
BCBenildo Cavada
Benildo CavadaCFC. A. Flores
C. A. Flores
RRR. A. Ribeiro
R. A. RibeiroThe natural physiological ligands for selectins are oligosaccharides found in glycoprotein or glycolipid molecules in cell membranes. In order to study the role of sugar residues in the in vivo lectin anti‐inflammatory effect, we tested three leguminous lectins with different carbohydrate binding affinities in the peritonitis and paw oedema models induced by carrageenin in rats. L. sericeus lectin was more anti‐inflammatory than D. virgata lectin, the effects being reversed by their specific binding sugars (N‐acetylglucosamine and α‐methylmannoside, respectively). However, V. macrocarpa, a galactose‐specific lectin, was not anti‐inflammatory. The proposed anti‐inflammatory activity of lectins could be due to a blockage of neutrophil‐selectin carbohydrate ligands. Thus, according to the present data, we suggest an important role for N‐acetylglucosamine residue as the major ligand for selectins on rat neutrophil membranes.
20 July 2017 in Inorganic Chemistry
Journal Article
FAFelipe Diógenes Abreu
Felipe Diógenes Abreu
TPTercio de F. Paulo
Tercio de F. PauloMGMarcelo H. Gehlen
Marcelo H. Gehlen
RARomulo Ando
Romulo AndoLLLuis Gonzaga De Franca Lopes
Luis Gonzaga De Franca LopesICIdalina Maria Moreira de Carvalho
Idalina Maria Moreira de Carvalho +4
1 January 2014 in BioMed Research International
Journal Article
Mayron VasconcelosFAFrancisco Vassiliepe Sousa Arruda
Francisco Vassiliepe Sousa Arruda
Victor Alves CarneiroHSHelton Colares Silva
Helton Colares Silva
KNKyria Santiago Nascimento
Kyria Santiago Nascimento
MPMaria O. Pereira
Maria O. Pereira +4
This study aimed to evaluate the abilities of plant and algae lectins to inhibit planktonic growth and biofilm formation in bacteria and yeasts. Initially, ten lectins were tested onStaphylococcus epidermidis, Staphylococcus aureus, Klebsiella oxytoca, Pseudomonas aeruginosa, Candida albicans, andC. tropicalisat concentrations of 31.25 to 250 μg/mL. The lectins fromCratylia floribunda(CFL),Vatairea macrocarpa(VML),Bauhinia bauhinioides(BBL),Bryothamnion seaforthii(BSL), andHypnea musciformis(HML) showed activities against at least one microorganism. Biofilm formation in the presence of the lectins was also evaluated; after 24 h of incubation with the lectins, the biofilms were analyzed by quantifying the biomass (by crystal violet staining) and by enumerating the viable cells (colony-forming units). The lectins reduced the biofilm biomass and/or the number of viable cells to differing degrees depending on the microorganism tested, demonstrating the different characteristics of the lectins. These findings indicate that the lectins tested in this study may be natural alternative antimicrobial agents; however, further studies are required to better elucidate the functional use of these proteins.
About Me
Prof. Dr. Edson Holanda Teixeira holds a degree in Dentistry from the Federal University of Ceará (1997) and a master’s degree (2001) and doctorate (2005) in Biochemistry from the Federal University of Ceará (2005). He is an Associate Professor I of the Department of Pathology and Legal Medicine of the Faculty of Medicine/Federal University of Ceará, Affiliate Member of the Brazilian Academy of Sciences, Researcher of the INCT Nanobiosimes Project (CNPq). He is a Professor and Vice-Coordinator of the Graduate Program in Natural Resources Biotechnology of the Federal University of Ceará, Professor of the Graduate Program in Pathology of the Federal University of Ceará, Collaborating Professor of the Graduate Program in Family Health of the Federal University of Ceará, Professor of the Northeast Network of Biotechnology (RENORBIO). He has experience in the areas of biochemistry and immunology, working mainly on the following topics: biological application of lectins and microbial biofilms. In the area of public health, he has experience in the management of public health systems and services.