Pneumonia is an infectious disease that affects the lungs and is one of the principal causes of death in children under five years old. The Chest X-ray images technique is one of the most used for diagnosing pneumonia. Several Machine Learning algorithms have been successfully used in order to provide computer-aided diagnosis by automatic classification of medical images. For its remarkable results, the Convolutional Neural Networks (models based on Deep Learning) that are widely used in Computer Vision tasks, such as classification of injuries and brain abnormalities, among others, stand out. In this paper, we present a transfer learning method that automatically classifies between 3883 chest X-ray images characterized as depicting pneumonia and 1349 labeled as normal. The proposed method uses the Xception Network pre-trained weights on ImageNet as an initialization. Our model is competitive with respect to state-of-the-art proposals. To make comparisons with other models, we have used four well-known performance measures, obtaining the following results: precision (0.84), recall (0.99), F1-score (0.91) and area under the ROC curve (0.97). These positive results allow us to consider our proposal as an alternative that can be useful in countries with a lack of equipment and specialized radiologists.

When facing certain problems in science, engineering or technology, it is not enough to find a solution, but it is essential to seek and find the best possible solution through optimization. In many cases the exact optimization procedures are not applicable due to the great computational complexity of the problems. As an alternative to exact optimization, there are approximate optimization algorithms, whose purpose is to reduce computational complexity by pruning some areas of the problem search space. To achieve this, researchers have been inspired by nature, because animals and plants tend to optimize many of their life processes. The purpose of this research is to design a novel bioinspired algorithm for numeric optimization: the Mexican Axolotl Optimization algorithm. The effectiveness of our proposal was compared against nine optimization algorithms (artificial bee colony, cuckoo search, dragonfly algorithm, differential evolution, firefly algorithm, fitness dependent optimizer, whale optimization algorithm, monarch butterfly optimization, and slime mould algorithm) when applied over four sets of benchmark functions (unimodal, multimodal, composite and competition functions). The statistical analysis shows the ability of Mexican Axolotl Optimization algorithm of obtained very good optimization results in all experiments, except for composite functions, where the Mexican Axolotl Optimization algorithm exhibits an average performance.

Machine learning in the medical area has become a very important requirement. The healthcare professional needs useful tools to diagnose medical illnesses. Classifiers are important to provide tools that can be useful to the health professional for this purpose. However, questions arise: which classifier to use? What metrics are appropriate to measure the performance of the classifier? How to determine a good distribution of the data so that the classifier does not bias the medical patterns to be classified in a particular class? Then most important question: does a classifier perform well for a particular disease? This paper will present some answers to the questions mentioned above, making use of classification algorithms widely used in machine learning research with datasets relating to medical illnesses under the supervised learning scheme. In addition to state-of-the-art algorithms in pattern classification, we introduce a novelty: the use of meta-learning to determine, a priori, which classifier would be the ideal for a specific dataset. The results obtained show numerically and statistically that there are reliable classifiers to suggest medical diagnoses. In addition, we provide some insights about the expected performance of classifiers for such a task.

As of the end of 2019, the world suffered from a disease caused by the SARS-CoV-2 virus, which has become the pandemic COVID-19. This aggressive disease deteriorates the human respiratory system. Patients with COVID-19 can develop symptoms that belong to the common flu, pneumonia, and other respiratory diseases in the first four to ten days after they have been infected. As a result, it can cause misdiagnosis between patients with COVID-19 and typical pneumonia. Some deep-learning techniques can help physicians to obtain an effective pre-diagnosis. The content of this article consists of a deep-learning model, specifically a convolutional neural network with pre-trained weights, which allows us to use transfer learning to obtain new retrained models to classify COVID-19, pneumonia, and healthy patients. One of the main findings of this article is that the following relevant result was obtained in the dataset that we used for the experiments: all the patients infected with SARS-CoV-2 and all the patients infected with pneumonia were correctly classified. These results allow us to conclude that the proposed method in this article may be useful to help physicians decide the diagnoses related to COVID-19 and typical pneumonia.