We developed an automatic method for staging periodontitis on dental panoramic radiographs using the deep learning hybrid method. A novel hybrid framework was proposed to automatically detect and classify the periodontal bone loss of each individual tooth. The framework is a hybrid of deep learning architecture for detection and conventional CAD processing for classification. Deep learning was used to detect the radiographic bone level (or the CEJ level) as a simple structure for the whole jaw on panoramic radiographs. Next, the percentage rate analysis of the radiographic bone loss combined the tooth long-axis with the periodontal bone and CEJ levels. Using the percentage rate, we could automatically classify the periodontal bone loss. This classification was used for periodontitis staging according to the new criteria proposed at the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. The Pearson correlation coefficient of the automatic method with the diagnoses by radiologists was0.73overall for the whole jaw (p < 0.01), and the intraclass correlation value0.91overall for the whole jaw (p < 0.01). The novel hybrid framework that combined deep learning architecture and the conventional CAD approach demonstrated high accuracy and excellent reliability in the automatic diagnosis of periodontal bone loss and staging of periodontitis.

Objectives: The purpose of this study was to automatically diagnose odontogenic cysts and tumors of both jaws on panoramic radiographs using deep learning. We proposed a novel framework of deep convolution neural network (CNN) with data augmentation for detection and classification of the multiple diseases. Methods: We developed a deep CNN modified from YOLOv3 for detecting and classifying odontogenic cysts and tumors of both jaws. Our data set of 1282 panoramic radiographs comprised 350 dentigerous cysts (DCs), 302 periapical cysts (PCs), 300 odontogenic keratocysts (OKCs), 230 ameloblastomas (ABs), and 100 normal jaws with no disease. In addition, the number of radiographs was augmented 12-fold by flip, rotation, and intensity changes. We evaluated the classification performance of the developed CNN by calculating sensitivity, specificity, accuracy, and area under the curve (AUC) for diseases of both jaws. Results: The overall classification performance for the diseases improved from 78.2% sensitivity, 93.9% specificity,91.3% accuracy, and 0.86 AUC using the CNN with unaugmented data set to 88.9% sensitivity, 97.2% specificity, 95.6% accuracy, and 0.94 AUC using the CNN with augmented data set. CNN using augmented data set had the following sensitivities, specificities, accuracies, and AUCs: 91.4%, 99.2%, 97.8%, and 0.96 for DCs, 82.8%, 99.2%, 96.2%, and 0.92 for PCs, 98.4%,92.3%,94.0%, and 0.97 for OKCs, 71.7%, 100%, 94.3%, and 0.86 for ABs, and 100.0%, 95.1%, 96.0%, and 0.97 for normal jaws, respectively. Conclusion: The CNN method we developed for automatically diagnosing odontogenic cysts and tumors of both jaws on panoramic radiographs using data augmentation showed high sensitivity, specificity, accuracy, and AUC despite the limited number of panoramic images involved.

Song IS, et al. Imaging Sci Dent. 2022 Jul;52:e37. https://doi.org/10.5624/isd.20220078

Disaster victim identification issues are especially critical and urgent after a large-scale disaster. The aim of this study was to suggest an automatic detection of natural teeth and dental treatment patterns based on dental panoramic radiographs (DPRs) using deep learning to promote its applicability as human identifiers. A total of 1 638 DPRs, of which the chronological age ranged from 20 to 49 years old, were collected from January 2000 to November 2020. This dataset consisted of natural teeth, prostheses, teeth with root canal treatment, and implants. The detection of natural teeth and dental treatment patterns including the identification of teeth number was done with a pre-trained object detection network which was a convolutional neural network modified by EfficientDet-D3. The objective metrics for the average precision were 99.1% for natural teeth, 80.6% for prostheses, 81.2% for treated root canals, and 96.8% for implants, respectively. The values for the average recall were 99.6%, 84.3%, 89.2%, and 98.1%, in the same order, respectively. This study showed outstanding performance of convolutional neural network using dental panoramic radiographs in automatically identifying teeth number and detecting natural teeth, prostheses, treated root canals, and implants. Key PointsIt is useful to use dental panoramic radiographs to perform the disaster victim identification (DVI).Individual dental treatment patterns could be unique and powerful characteristics as human identifier.Deep learning can automatically detect teeth and dental treatment patterns with favourable accuracy.Constructing a big database including detected teeth information would make it possible to fully automate entire process of DVI.

The bone mineral density (BMD) measurement is a direct method of estimating human bone mass for diagnosing osteoporosis, and performed to objectively evaluate bone quality before implant surgery in dental clinics. The objective of this study was to validate the accuracy and reliability of BMD measurements made using quantitative cone-beam CT (CBCT) image based on deep learning by applying the method to clinical data from actual patients. Datasets containing 7500 pairs of CT and CBCT axial slice images from 30 patients were used to train a previously developed deep-learning model (QCBCT-NET). We selected 36 volumes of interest in the CBCT images for each patient in the bone regions of potential implants sites on the maxilla and mandible. We compared the BMDs shown in the quantitative CBCT (QCBCT) images with those in the conventional CBCT (CAL_CBCT) images at the various bone sites of interest across the entire field of view (FOV) using the performance metrics of the MAE, RMSE, MAPE (mean absolute percentage error), R² (coefficient of determination), and SEE (standard error of estimation). Compared with the ground truth (QCT) images, the accuracy of the BMD measurements from the QCBCT images showed an RMSE of 83.41 mg/cm³, MAE of 67.94 mg/cm³, and MAPE of 8.32% across all the bone sites of interest, whereas for the CAL_CBCT images, those values were 491.15 mg/cm³, 460.52 mg/cm³, and 54.29%, respectively. The linear regression between the QCBCT and QCT images showed a slope of 1.00 and a R² of 0.85, whereas for the CAL_CBCT images, those values were 0.32 and 0.24, respectively. The overall SEE between the QCBCT images and QCT images was 81.06 mg/cm³, whereas the SEE for the CAL_CBCT images was 109.32 mg/cm³. The QCBCT images thus showed better accuracy, linearity, and uniformity than the CAL_CBCT images across the entire FOV. The BMD measurements from the quantitative CBCT images showed high accuracy, linearity, and uniformity regardless of the relative geometric positions of the bone in the potential implant site. When applied to actual patient CBCT images, the CBCT-based quantitative BMD measurement based on deep learning demonstrated high accuracy and reliability across the entire FOV.