Severino Alencar

Prof. Severino Alencar

Escola Superior de Agricultura “Luiz de Queiroz”, University of São Paulo, São Paulo, Brazil
orcid

Research Focus & Metrics

Academic Career Length

27Years (2000-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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14 March 2002 in Journal of Agricultural and Food Chemistry
Verified
Journal Article
Closed access
YPYong K. Park
Yong K. Park
SASeverino M. Alencar
Severino M. Alencar
CAClaudio L. Aguiar
Claudio L. Aguiar

1 September 2007 in Journal of Ethnopharmacology
Verified
Journal Article
Closed access
SAS.M. Alencar
S.M. Alencar
Tatiane Luiza Cadorin OldoniTatiane Luiza Cadorin Oldoni
Tatiane Luiza Cadorin Oldoni
MCM.L. Castro
M.L. Castro
ICI.S.R. Cabral
I.S.R. Cabral
CCC.M. Costa-Neto
C.M. Costa-Neto
MIM. Ikegaki
M. Ikegaki

1 January 2012 in Brazilian Dental Journal
Verified
Journal Article
Open access
PDF file
EGEugenio José Garcia
Eugenio José Garcia
Tatiane Luiza Cadorin OldoniTatiane Luiza Cadorin Oldoni
Tatiane Luiza Cadorin Oldoni
SASeverino Matias de Alencar
Severino Matias de Alencar
ARAlessandra Reis
Alessandra Reis
ALAlessandro D. Loguercio
Alessandro D. Loguercio
RGRosa Helena Miranda Grande
Rosa Helena Miranda Grande
The aim of this study was to assess, using the DPPH assay, the antioxidant activity of several substances that could be proposed to immediately revert the problems caused by bleaching procedures. The percentage of antioxidant activity (AA%) of 10% ascorbic acid solution (AAcidS), 10% ascorbic acid gel (AAcidG), 10% sodium ascorbate solution (SodAsS), 10% sodium ascorbate gel (SodAsG), 10% sodium bicarbonate (Bicarb), Neutralize® (NE), Desensibilize® (DES), catalase C-40 at 10 mg/mL (CAT), 10% alcohol solution of alpha-tocopherol (VitE), Listerine® (LIS), 0.12% chlorhexidine (CHX), Croton Lechleri (CL), 10 % aqueous solution of Uncaria Tomentosa (UT), artificial saliva (ArtS) and 0.05% sodium fluoride (NaF) was assessed in triplicate by 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) free radical assay. All substances exhibited antioxidant activity, except for CL. AAcidS, AAcidG and VitE exhibited the highest AA% (p<0.05). On the contrary, CHX, NE, LIS and NaF showed the lowest AA% (p<0.05). In conclusion, AAcidS, AAcidG, SodAsS, SodAsG and VitE presented the highest antioxidant activity among substances tested in this study. The DPPH assay provides an easy and rapid way to evaluate potential antioxidants.

22 April 2015 in Molecules
Verified
Journal Article
Open access
PDF file
IFIrlan Almeida Freires
Irlan Almeida Freires
CDCarina Denny
Carina Denny
BBBruna Benso
Bruna Benso
SASeverino Matias De Alencar
Severino Matias De Alencar
PRPedro Luiz Rosalen
Pedro Luiz Rosalen
Dental caries remains the most prevalent and costly oral infectious disease worldwide. Several methods have been employed to prevent this biofilm-dependent disease, including the use of essential oils (EOs). In this systematic review, we discuss the antibacterial activity of EOs and their isolated constituents in view of a potential applicability in novel dental formulations. Seven databases were systematically searched for clinical trials, in situ, in vivo and in vitro studies addressing the topic published up to date. Most of the knowledge in the literature is based on in vitro studies assessing the effects of EOs on caries-related streptococci (mainly Streptococcus mutans) and lactobacilli, and on a limited number of clinical trials. The most promising species with antibacterial potential against cariogenic bacteria are: Achillea ligustica, Baccharis dracunculifolia, Croton cajucara, Cryptomeria japonica, Coriandrum sativum, Eugenia caryophyllata, Lippia sidoides, Ocimum americanum, and Rosmarinus officinalis. In some cases, the major phytochemical compounds determine the biological properties of EOs. Menthol and eugenol were considered outstanding compounds demonstrating an antibacterial potential. Only L. sidoides mouthwash (1%) has shown clinical antimicrobial effects against oral pathogens thus far. This review suggests avenues for further non-clinical and clinical studies with the most promising EOs and their isolated constituents bioprospected worldwide.

14 February 2018 in PLOS ONE
Verified
Journal Article
Open access
PDF file
MTMaria Augusta Tremocoldi
Maria Augusta Tremocoldi
PRPedro Luiz Rosalen
Pedro Luiz Rosalen
MFMarcelo Franchin
Marcelo Franchin
AMAdna Prado Massarioli
Adna Prado Massarioli
CDCarina Denny
Carina Denny
SASeverino Matias De Alencar
Severino Matias De Alencar
This study aimed to evaluate the antioxidant, anti-inflammatory, and cytotoxic properties and phenolic composition of peel and seed of avocado varieties Hass and Fuerte using green solvents. Ethanol soluble compounds were identified in peel and seed of both varieties using HPLC-MS/MS and quantified using HPLC-DAD. Agro-industrial by-products of both varieties exhibited high radical scavenging activity against synthetic free radicals (DPPH and ABTS) and reactive oxygen species (peroxyl, superoxide, and hypochlorous acid) and high ability to reduce Fe3+ to Fe2+. The main compounds with significant contribution to the antioxidant activity determined by online HPLC-ABTS●+ analyses were procyanidin B2 and epicatechin in the peel and trans-5-O-caffeoyl-D-quinic acid, procyanidin B1, catechin, and epicatechin in the seed. Peel of Fuerte significantly suppressed TNF-α and nitric oxide (NO) release (459.3 pg/mL and 8.5 μM, respectively), possibly because of the high phenolic content and antioxidant activity detected. Avocado agro-industrial by-products can be used for food and pharmaceutical purposes due to their antioxidant and anti-inflammatory properties.

1 March 2011 in LWT
Verified
Journal Article
Closed access
MNMírian Pozippe Nori
Mírian Pozippe Nori
Carmen Silvia Favaro-TrindadeCarmen Silvia Favaro-Trindade
Carmen Silvia Favaro-Trindade
SASeverino Matias de Alencar
Severino Matias de Alencar
MTMarcelo Thomazini
Marcelo Thomazini
JBJulio Cesar de Carvalho Balieiro
Julio Cesar de Carvalho Balieiro
CCCarmen Josefina Contreras Castillo
Carmen Josefina Contreras Castillo