Fatty acids are widely occurring in natural fats and dietary oils and they are known to have antibacterial and antifungal properties. However, little is known on the antibacterial and antifungal properties of the blind-your-eye mangrove (Excoecaria agallocha) and this study for the first time determines the fatty acid composition and the antibacterial and antifungal activities of Fatty Acid Methyl Esters (FAME) of the blind-your-eye mangrove plant found along the coastal areas of south India. Gorduras naturais e óleos são abundantes em ácidos graxos que apresentam atividade antibacteriana e antifúngica. Entretanto, pouco se sabe sobre a atividade antibacteriana e antifúngica de ésteres metílicos de ácidos graxos de mangue "blind-your-eye" (Excoecaria agallocha). Esse estudo relata, pela primeira vez, a composição em ácidos graxos e a atividade antibacteriana e antifúngica de ésteres metílicos de ácidos graxos (FAME) de mangue "blind-your-eye" encontrado ao longo de áreas costeiras do sul da India
In last few years, the use of zebrafish (Danio rerio) in scientific research is growing very rapidly. Initially, it was a popular as a model of vertebrate development because zebrafish embryos are transparent and also develop rapidly. Presently, the research using zebrafish is expanding into other areas such as pharmacology, clinical research as a diseases model and interestingly in drug discovery. The use of zebrafish in pharmaceutical research and discovery and drug development is mainly screening of lead compounds, target identification, target validation, morpholino oligonucleotide screens, assay development for drug discovery, physiology based drug discovery, quantitative structure-activity relationship (QSAR) and structure – activity relationships (SAR) study and drug toxicity study. In this paper, we have described properly all the areas of dug discovery where zebrafish is used as a tool. We are hopeful that the use of these techniques or methods will make the zebrafish a prominent model in drug discovery and development research in the forthcoming years.
A key characteristic of human language efficiency is that more frequently used words tend to be shorter in length—the ‘law of brevity’. To date, no test of this relationship between frequency of use and length has been carried out on non-human animal vocal communication. We show here that the vocal repertoire of the Formosan macaque ( Macaca cyclopis ) conforms to the pattern predicted by the law of brevity, with an inverse relationship found between call duration and rate of utterance. This finding provides evidence for coding efficiency in the vocal communication system of this species, and indicates commonality in the basic structure of the coding system between human language and vocal communication in this non-human primate.
26 October 2020 in Journal of Racial and Ethnic Health Disparities
In response to the coronavirus pandemic, several countries have imposed curfews, quarantines, and lockdowns to restrict the spread of the infection among people. India had initiated a nationwide lockdown to combat the pandemic starting from the last week of March until the end of May 2020. But, the lockdown had continued subsequently in several red zones across parts of the country for few months. However, scientists have criticized the government’s abrupt lockdown since it prevented people from preparing for the worst aftermath. Besides, the curfews have blocked millions of impoverished migrant workers from leaving cities to return to their homes in distant rural villages. As a result, the destitute workers have endured enormous hardship and outright discrimination desolately leading to their added physical and mental distress, pain, suffering, and death. Most of the victims of the lockdown have belonged to the economically distressed lower social classes of the Indian caste hierarchy. This article outlines their sufferings triggered by the long drawn-out lockdown episode.