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Prof. Jacek Tabarkiewicz
Department of Human Immunology, College of Medical Science, Institute of Medicine, University of Rzeszów, Rzeszow, Poland
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Academic Career Length
33Years (1994-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications1 March 2012 in Journal of Reproductive Immunology
Journal Article
DDDorota Darmochwal-Kolarz
Dorota Darmochwal-KolarzMKMagdalena Kludka-Sternik
Magdalena Kludka-Sternik
JTJacek Tabarkiewicz
Jacek TabarkiewiczBKBogdan Kolarz
Bogdan KolarzJRJacek Roliński
Jacek RolińskiJOJan Oleszczuk
Jan Oleszczuk
+1
11 June 2015 in Archivum Immunologiae et Therapiae Experimentalis
Journal Article
JTJacek Tabarkiewicz
Jacek TabarkiewiczKPKatarzyna Pogoda
Katarzyna Pogoda
AKAgnieszka Karczmarczyk
Agnieszka Karczmarczyk
PPPiotr Pozarowski
Piotr Pozarowski
Krzysztof GiannopoulosThe end of twentieth century has introduced some changes into T helper (Th) cells division. The identification of the new subpopulation of T helper cells producing IL-17 modified model of Th1–Th2 paradigm and it was named Th17. High abilities to stimulate acute and chronic inflammation made these cells ideal candidate for crucial player in development of autoimmune disorders. Numerous publications based on animal and human models confirmed their pivotal role in pathogenesis of human systemic and organ-specific autoimmune diseases. These findings made Th17 cells and pathways regulating their development and function a good target for therapy. Therapies based on inhibition of Th17-dependent pathways are associated with clinical benefits, but on the other hand are frequently inducing adverse effects. In this review, we attempt to summarize researches focused on the importance of Th17 cells in development of human autoimmune diseases as well as effectiveness of targeting IL-17 and its pathways in pre-clinical and clinical studies.
1 September 2016 in Journal of Reproductive Immunology
Journal Article
MGMarek Zbigniew Gogacz
Marek Zbigniew GogaczIWIzabela Winkler
Izabela Winkler
Agnieszka Bojarska-JunakJTJacek Tabarkiewicz
Jacek Tabarkiewicz
Andrzej SemczukAAAneta Adamiak
Aneta Adamiak +1
30 June 2005 in Leukemia
Journal Article
IHIwona Hus
Iwona HusJRJacek Roliński
Jacek RolińskiJTJacek Tabarkiewicz
Jacek TabarkiewiczKWK Wojas
K Wojas
Agnieszka Bojarska-JunakMSM Schmitt
M Schmitt +3
11 June 2007 in American Journal of Reproductive Immunology
Journal Article
DDDorota Darmochwal-Kolarz
Dorota Darmochwal-KolarzSSS. Saito
S. Saito
JRJacek Roliński
Jacek RolińskiJTJacek Tabarkiewicz
Jacek TabarkiewiczBKBogdan Kolarz
Bogdan KolarzJOJ. Oleszczuk
J. Oleszczuk
+1
1 January 2017 in Stem Cells International
Journal Article
BKBeata Kocan
Beata KocanAMAleksandra Maziarz
Aleksandra Maziarz
JTJacek Tabarkiewicz
Jacek TabarkiewiczTOTakahiro Ochiya
Takahiro Ochiya
ABAgnieszka Banaś-Ząbczyk
Agnieszka Banaś-ZąbczykThere has been an increased interest in mesenchymal stem cells from adipose tissue, due to their abundance and accessibility with no ethical concerns. Their multipotent properties make them appropriate for regenerative clinical applications. It has been shown that adipose-derived stem cells (ASCs) may differ between the origin sites. Moreover, a variety of internal and external factors may affect their biological characteristics, as what we aimed to highlight in this review. It has been demonstrated that ASCs secrete multiple trophic factors that are capable of stimulating cell proliferation and differentiation and migration of various cell types. Particular attention should be given to exosomes, since it is known that they contribute to the paracrine effects of MSCs. Secretion of trophic agents by ASCs is thought to be in a greater importance for regenerative medicine applications, rather than cells engraftment to the site of injury and their differentiation ability. The surface marker profile of ASCs seems to be similar to that of the mesenchymal stem cells from bone marrow, although some molecular differences are observed. Thus, in this review, we have attempted to define trophic activity, as well as phenotypic characterization of ASCs, as crucial factors for therapeutic usage.
About Me
Jacek Tabarkiewicz graduated from the Medical University of Lublin, where he continued his professional career at the Department and Department of Clinical Immunology, obtaining the degree of Ph.D. Since 2014, he has been associated with the University of Rzeszów, where from 2015 to 2019 he was the director of the Natural and Medical Center for Innovative Research. He is the head of the Department of Human Immunology and head of the Laboratory of Translational Research in Medicine. He is a member of the Management Board of the Polish Society of Cytometry, and a member and former member of the International Society for Dendritic Cell & Vaccine Science. He serves as an Associate Editor of the Journal of Immunology Research a senior member of the editorial board of the American Journal of Cancer Therapy and Pharmacology; a member of the editorial committee of the World Journal of Respirology and SciTz Gynecology and Reproductive Medicine, as well as editor of the Immunology and experimental therapies section of the European Journal of Clinical and Experimental Medicine. The main trends of his research are issues of cancer immunology and the pathogenesis of autoimmune diseases. He is a doctor working at the Second Department of Pediatrics, Endocrinology, and Pediatric Diabetology focusing on the issues of therapy of autoimmune childhood diseases and myositis ossificans.