In this paper, we introduce the Yang transform homotopy perturbation method (YTHPM), which is a novel method. We provide formulae for the Yang transform of Caputo-Fabrizio fractional order derivatives. We derive an algorithm for the solution of Caputo-Fabrizio (CF) fractional order partial differential equation in series form and show its convergence to the exact solution. To demonstrate the novel approach, we include some examples with detailed solutions. We use tables and graphs to compare the exact and approximate solutions.

HIV-1 infection is a dangerous diseases like Cancer, AIDS, etc. Many mathematical models have been introduced in the literature, which are investigated with different approaches. In this article, we generalize the HIV-1 model through nonsingular fractional operator. The non-integer mathematical model of HIV-1 infection under the Caputo-Fabrizio derivative is presented in this paper. The concept of Picard-Lindelof and fixed-point theory are used to address the existence of a unique solution to the HIV-1 model under the suggested operator. Also, the stability of the suggested model is proved through the Picard iteration and fixed point theory approach. The model's approximate solution is constructed through three steps Adams-Bashforth numerical method. Numerical simulations are provided for different values of fractional-order to study the complex dynamics of the model. Lastly, we provide the oscillatory and chaotic behavior of the proposed model for various fractional orders.