Research area of interest: • Evaluating mechanisms and functions of swine feed additives by studying growth performance, nutrient digestibility, immune functions, and microbiome during the lifetime of production. • Identifying strategies from both nutritional and nonnutritional to help promote production efficiency, and sustainability. • Evaluating the long-term impact of programing in early life on the health of swine: a multi-omics approach. • Nutrition intervention on longevity of sow and transgenerational effect.