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Objective: Rheumatoid arthritis and age are associated with high sarcopenia risk. Exercise is an effective treatment for preventing muscle mass loss in older adult populations. It remains unclear whether exercise affects muscle mass in people with rheumatoid arthritis. Thus, this meta-analysis investigated the effect of exercise on muscle mass gain in patients with rheumatoid arthritis. Data sources: PubMed, EMBASE, the Cochrane Library, the Physiotherapy Evidence Database (PEDro), the China Knowledge Resource Integrated Database, and Google Scholar were systematically searched until June 2021. Methods: The present study was conducted according to the guidelines recommended by the Preferred Reporting Items for Systematic Reviews and Meta-Analysis. Randomized controlled trials (RCTs) that reported the effects of exercise on muscle mass for rheumatoid arthritis were identified. The included RCTs were subject to meta-analysis and risk of bias assessment. Subgroup and random-effects meta-regression analyses were performed to identify any heterogeneity ( I2) of treatment effects across studies. Results: We included nine RCTs with a median PEDro score of 6/10 (range: 4/10–8/10). The weighted mean effect size for muscle mass was 0.77 (95% CI: 0.30–1.24; P = 0.001; I2 = 77%). Meta-regression analyses indicated that the disease duration significantly explained variance of treatment effects across studies (β = −0.006, R2 = 69.7%, P = 0.005). Conclusions: Exercise therapy effectively increased muscle mass in patients with rheumatoid arthritis. Treatment effects may be attenuated in those who have had rheumatoid arthritis for a relatively long time.
Chun-De Liao; Hung-Chou Chen; Shih-Wei Huang; Tsan-Hon Liou. Exercise therapy for sarcopenia in rheumatoid arthritis: A meta-analysis and meta-regression of randomized controlled trials. Clinical Rehabilitation 2021, 1 .
AMA StyleChun-De Liao, Hung-Chou Chen, Shih-Wei Huang, Tsan-Hon Liou. Exercise therapy for sarcopenia in rheumatoid arthritis: A meta-analysis and meta-regression of randomized controlled trials. Clinical Rehabilitation. 2021; ():1.
Chicago/Turabian StyleChun-De Liao; Hung-Chou Chen; Shih-Wei Huang; Tsan-Hon Liou. 2021. "Exercise therapy for sarcopenia in rheumatoid arthritis: A meta-analysis and meta-regression of randomized controlled trials." Clinical Rehabilitation , no. : 1.
Older adults with knee osteoarthritis (KOA) are at high risk of sarcopenia. Protein-rich nutritional composition supplementation (PS) combined with resistance exercise training (RET) improves muscle gains and facilitates physical activity in older adults. However, whether PS augments the effects of RET on muscle mass and PA in patients with KOA remains unclear. Therefore, this study identified the effects of PS on sarcopenic indices and PA in older women with KOA subjected to an RET program. Eligible older women aged 60–85 years and diagnosed as having KOA were randomly assigned to either the experimental group (EG) or the control group (CG). Both groups performed RET twice a week for 12 weeks. The EG received additional PS during this period. Outcome measures included appendicular lean mass index, walking speed, physical activity, and scores on the Western Ontario and McMaster Universities Osteoarthritis Index—WOMAC). All measures were tested at baseline and after intervention. With participant characteristics and baseline scores as covariates, analysis of variance was performed to identify between-group differences in changes in all outcome measures after intervention. Statistical significance was defined as p< 0.05. Compared with the CG, the EG achieved greater changes in appendicular lean mass index (adjusted mean difference (aMD) = 0.19 kg/m2, p< 0.01), physical activity (aMD = 30.0 MET-hour/week, p< 0.001), walking speed (aMD = 0.09 m/s, p< 0.05), and WOMAC global function (aMD = −8.21, p< 0.001) after intervention. In conclusion, PS exerted augmentative effects on sarcopenic indices, physical activity, and perceived global WOMAC score in older women with KOA through 12 weeks of RET.
Chun-De Liao; Yi-Hung Liao; Tsan-Hon Liou; Ching-Ya Hsieh; Yu-Chi Kuo; Hung-Chou Chen. Effects of Protein-Rich Nutritional Composition Supplementation on Sarcopenia Indices and Physical Activity during Resistance Exercise Training in Older Women with Knee Osteoarthritis. Nutrients 2021, 13, 2487 .
AMA StyleChun-De Liao, Yi-Hung Liao, Tsan-Hon Liou, Ching-Ya Hsieh, Yu-Chi Kuo, Hung-Chou Chen. Effects of Protein-Rich Nutritional Composition Supplementation on Sarcopenia Indices and Physical Activity during Resistance Exercise Training in Older Women with Knee Osteoarthritis. Nutrients. 2021; 13 (8):2487.
Chicago/Turabian StyleChun-De Liao; Yi-Hung Liao; Tsan-Hon Liou; Ching-Ya Hsieh; Yu-Chi Kuo; Hung-Chou Chen. 2021. "Effects of Protein-Rich Nutritional Composition Supplementation on Sarcopenia Indices and Physical Activity during Resistance Exercise Training in Older Women with Knee Osteoarthritis." Nutrients 13, no. 8: 2487.
Aging and osteoarthritis are associated with high risk of muscle mass loss, which leads to physical disability; this loss can be effectively alleviated by diet (DI) and exercise (ET) interventions. This study investigated the relative effects of different types of diet, exercise, and combined treatment (DI+ET) on muscle mass and functional outcomes in individuals with obesity and lower-limb osteoarthritis. A comprehensive search of online databases was performed to identify randomized controlled trials (RCTs) examining the efficacy of DI, ET, and DI+ET in patients with obesity and lower-extremity osteoarthritis. The included RCTs were analyzed through network meta-analysis and risk-of-bias assessment. We finally included 34 RCTs with a median (range/total) Physiotherapy Evidence Database score of 6.5 (4–8/10). DI plus resistance ET, resistance ET alone, and aerobic ET alone were ranked as the most effective treatments for increasing muscle mass (standard mean difference (SMD) = 1.40), muscle strength (SMD = 1.93), and walking speed (SMD = 0.46). Our findings suggest that DI+ET is beneficial overall for muscle mass in overweight or obese adults with lower-limb osteoarthritis, especially those who are undergoing weight management.
Shu-Fen Chu; Tsan-Hon Liou; Hung-Chou Chen; Shih-Wei Huang; Chun-De Liao. Relative Efficacy of Weight Management, Exercise, and Combined Treatment for Muscle Mass and Physical Sarcopenia Indices in Adults with Overweight or Obesity and Osteoarthritis: A Network Meta-Analysis of Randomized Controlled Trials. Nutrients 2021, 13, 1992 .
AMA StyleShu-Fen Chu, Tsan-Hon Liou, Hung-Chou Chen, Shih-Wei Huang, Chun-De Liao. Relative Efficacy of Weight Management, Exercise, and Combined Treatment for Muscle Mass and Physical Sarcopenia Indices in Adults with Overweight or Obesity and Osteoarthritis: A Network Meta-Analysis of Randomized Controlled Trials. Nutrients. 2021; 13 (6):1992.
Chicago/Turabian StyleShu-Fen Chu; Tsan-Hon Liou; Hung-Chou Chen; Shih-Wei Huang; Chun-De Liao. 2021. "Relative Efficacy of Weight Management, Exercise, and Combined Treatment for Muscle Mass and Physical Sarcopenia Indices in Adults with Overweight or Obesity and Osteoarthritis: A Network Meta-Analysis of Randomized Controlled Trials." Nutrients 13, no. 6: 1992.
Background: Major depressive disorder (MDD) is a highly prevalent mental disorder which causes public health burden and personal disabilities. In people with mental illness, unemployment is an index character of functional impairment. Methods: Using the Taiwan Databank of Persons with Disability (TDPD), we collected the WHO Disability Assessment Schedule 2.0 (WHODAS 2.0) scores for people with MDD-associated disability. We recorded and analyzed the scores of participants during a 3-year period to determine the impact of employment on the trajectory of functional change. Logistic regression was performed to analyze the association between employment and changes in WHODAS 2.0 scores. Results: In people with MDD-associated disability, unemployed individuals present a worse function initially compared to employed individuals. After a 3-year period, the employed group showed a significant functional improvement in the domains of cognition, mobility, and participation. In logistic regression, the odds of having functional improvement were twice as high for those who were employed compared with those who were not. Conclusions: Higher odds of having functional improvement were noted in participants who stay in employment. Programs and strategies to help people with MDD-associated disability resume work warrant more clinical attention and supportive policies from the government.
Yu-Chen Chiang; Tsan-Hon Liou; Hsin-Chien Lee; Reuben Escorpizo. Using WHODAS 2.0 to Assess Functional Impairment in People with Depression: Should Employment Receive More Attention? International Journal of Environmental Research and Public Health 2021, 18, 4552 .
AMA StyleYu-Chen Chiang, Tsan-Hon Liou, Hsin-Chien Lee, Reuben Escorpizo. Using WHODAS 2.0 to Assess Functional Impairment in People with Depression: Should Employment Receive More Attention? International Journal of Environmental Research and Public Health. 2021; 18 (9):4552.
Chicago/Turabian StyleYu-Chen Chiang; Tsan-Hon Liou; Hsin-Chien Lee; Reuben Escorpizo. 2021. "Using WHODAS 2.0 to Assess Functional Impairment in People with Depression: Should Employment Receive More Attention?" International Journal of Environmental Research and Public Health 18, no. 9: 4552.
Burn injuries cause disability and functional limitations in daily living. In a 2015 fire explosion in Taiwan, 499 young people sustained burn injuries. The construction of an effective and comprehensive rehabilitation program that enables patients to regain their previous function is imperative. The International Classification of Functioning, Disability, and Health (ICF) includes multiple dimensions that can contribute to meeting this goal. An ICF core set was developed in this study for Taiwanese patients with burns. A consensus process using three rounds of the Delphi technique was employed. A multidisciplinary team of 30 experts from various institutions was formed. The questionnaire used in this study comprised 162 ICF second-level categories relevant to burn injuries. A 5-point Likert scale was used, and participants assigned a weight to the effect of each category on daily activities after burns. The consensus among ratings was assessed using Spearman’s ρ and semi-interquartile range indices. The core set for post-acute SCI was developed from categories that attained a mean score of ≥4.0 in the third round of the Delphi exercise. The core ICF set contained 68 categories. Of these, 19 comprised the component of body functions, 5 comprised body structures, 37 comprised activities and participation, and 7 comprised environmental factors. This preliminary core set offers a comprehensive system for disability assessment and verification following burn injury. The core set provides information for effective rehabilitation strategy setting for patients with burns. Further feasibility and validation studies are required in the future.
Yu-Ru Lin; Jr-Yi Wang; Shun-Cheng Chang; Kwang-Hwa Chang; Hung-Chou Chen; Reuben Escorpizo; Shih-Wei Huang; Tsan-Hon Liou. Developing a Delphi-Based Comprehensive Core Set from the International Classification of Functioning, Disability, and Health Framework for the Rehabilitation of Patients with Burn Injuries. International Journal of Environmental Research and Public Health 2021, 18, 3970 .
AMA StyleYu-Ru Lin, Jr-Yi Wang, Shun-Cheng Chang, Kwang-Hwa Chang, Hung-Chou Chen, Reuben Escorpizo, Shih-Wei Huang, Tsan-Hon Liou. Developing a Delphi-Based Comprehensive Core Set from the International Classification of Functioning, Disability, and Health Framework for the Rehabilitation of Patients with Burn Injuries. International Journal of Environmental Research and Public Health. 2021; 18 (8):3970.
Chicago/Turabian StyleYu-Ru Lin; Jr-Yi Wang; Shun-Cheng Chang; Kwang-Hwa Chang; Hung-Chou Chen; Reuben Escorpizo; Shih-Wei Huang; Tsan-Hon Liou. 2021. "Developing a Delphi-Based Comprehensive Core Set from the International Classification of Functioning, Disability, and Health Framework for the Rehabilitation of Patients with Burn Injuries." International Journal of Environmental Research and Public Health 18, no. 8: 3970.
Osteoarthritis is one of the leading causes of disability. Total knee arthroplasty (TKA) is a surgical intervention for patients with severe osteoarthritis. Post TKA rehabilitation is crucial for improving patient’s quality of life. However, traditional rehabilitation has only focused on physical function; a systemic analysis of other dimensions such as social participation and environmental factors of post TKA rehabilitation is lacking. The aim of this study was to develop a core set from the International Classification of Functioning, Disability and Health (ICF) to create a comprehensive rehabilitation program for patients with osteoarthritis post TKA. Before the Delphi-based consensus process, a literature review process was performed for related ICF categories selection. We used a three-round Delphi-based consensus among 20 physical therapists with orthopedic rehabilitation expertise in a university-based hospital. A five-point Likert scale was used to rate the importance of each item. The consensus of ratings was analyzed using Spearman’s rho and semi-interquartile range indices. The ICF core set for post TKA rehabilitation was determined based on a high level of consensus and a mean score of ≥4.0 in the third Delphi-based consensus round. The ICF core set comprised 32 categories, with 13 regarding body function, four regarding body structures, nine regarding activities and participation, four regarding environmental factors, and two regarding personal factors. Our ICF core set for post TKA rehabilitation can provide information on effective rehabilitation strategies and goal setting for patients post TKA. However, further validation and feasibility assessments are warranted.
Shih-Wei Huang; Yi-Wen Chen; Reuben Escorpizo; Chun-De Liao; Tsan-Hon Liou. Development International Classification of Functioning, Disability and Health Core Set for Post Total Knee Replacement Rehabilitation Program: Delphi-Based Consensus Study in Taiwan. International Journal of Environmental Research and Public Health 2021, 18, 1630 .
AMA StyleShih-Wei Huang, Yi-Wen Chen, Reuben Escorpizo, Chun-De Liao, Tsan-Hon Liou. Development International Classification of Functioning, Disability and Health Core Set for Post Total Knee Replacement Rehabilitation Program: Delphi-Based Consensus Study in Taiwan. International Journal of Environmental Research and Public Health. 2021; 18 (4):1630.
Chicago/Turabian StyleShih-Wei Huang; Yi-Wen Chen; Reuben Escorpizo; Chun-De Liao; Tsan-Hon Liou. 2021. "Development International Classification of Functioning, Disability and Health Core Set for Post Total Knee Replacement Rehabilitation Program: Delphi-Based Consensus Study in Taiwan." International Journal of Environmental Research and Public Health 18, no. 4: 1630.
Introduction: Knee osteoarthritis (KOA) is associated with an increased risk of sarcopenia, and aging-related muscle deterioration continues after total knee replacement (TKR). Low skeletal muscle mass index may influence postoperative rehabilitation outcomes. Through this study, we aimed to investigate the impact of preoperative sarcopenia on clinical outcomes after postoperative rehabilitation in older Asian adults. Methods: A total of 190 older adults (39 men, 151 women) were enrolled from two previous trials and were classified as having no sarcopenia, class I sarcopenia, or class II sarcopenia according to definitions provided by the Asian Working Group for Sarcopenia (AWGS) and the European Working Group on Sarcopenia in Older People (EWGSOP). All patients were retrospectively analyzed before (T0) and after (T1) TKR rehabilitation and 10 months after surgery (T2). The outcome measures included the timed up-and-go test (TUGT), gait speed (GS), timed chair rise (TCR), and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain and physical difficulty (WOMAC-PF). With patient characteristics and T0 scores as covariates, an analysis of variance was performed to identify intergroup differences in changes of all outcome measures at T1 and T2. Results: According to the definitions of both the AWGS and EWGSOP, patients with class I and class II sarcopenia exhibited minor changes in TUGT, GS, TCR, and WOMAC-PF at T1 and T2 (all p < 0.05), compared with those without sarcopenia. For patients classified as having sarcopenia based on AWGS and EWGSOP definitions, no significant intergroup differences in WOMAC pain score was observed at T1 or T2 (all p > 0.05). Conclusions: Sarcopenia independently had negative impacts on the treatment effects of rehabilitation on physical mobility but not on pain outcome after TKR in older adults with KOA.
Chun-De Liao; Hung-Chou Chen; Shih-Wei Huang; Tsan-Hon Liou. Impact of sarcopenia on rehabilitation outcomes after total knee replacement in older adults with knee osteoarthritis. Therapeutic Advances in Musculoskeletal Disease 2021, 13, 1 .
AMA StyleChun-De Liao, Hung-Chou Chen, Shih-Wei Huang, Tsan-Hon Liou. Impact of sarcopenia on rehabilitation outcomes after total knee replacement in older adults with knee osteoarthritis. Therapeutic Advances in Musculoskeletal Disease. 2021; 13 ():1.
Chicago/Turabian StyleChun-De Liao; Hung-Chou Chen; Shih-Wei Huang; Tsan-Hon Liou. 2021. "Impact of sarcopenia on rehabilitation outcomes after total knee replacement in older adults with knee osteoarthritis." Therapeutic Advances in Musculoskeletal Disease 13, no. : 1.
The aim of this study was to explore the association between employment status and World Health Organization Disability Assessment Schedule, Second Edition (WHODAS 2.0) scores of working-age subjects with hearing impairment. The data of 18,573 working-age subjects (age ≥ 18 and <65 years) with disabling hearing impairment were obtained from the Taiwan Data Bank of Persons with Disability (TDPD) for the period from 11 July 2012 to 31 October 2018. Demographic data and WHODAS 2.0 scores for each domain were analyzed to identify their relationship with employment status. Unemployed subjects with disabling hearing impairment had higher WHODAS 2.0 scores in all domains compared with the employed subjects. Binary logistic regression revealed that older age, female sex, lower educational level, institutional residence, rural residence, lower family income, and moderate to severe impairment were more strongly associated with unemployment status. The data in this large population-based study offer comprehensive information on important factors associated with the employment status of people with disabling hearing impairment. Early identification of risks of unemployment of patients with hearing impairment can raise awareness for aggressive community and government campaigns regarding public health to improve the self-confidence, social participation, and related psycho-social wellbeing of people.
Pin-Zhir Chao; Shih-Wei Huang; Reuben Escorpizo; Wen-Chou Chi; Chia-Feng Yen; Hua-Fang Liao; Yi-Wen Chen; Tsan-Hon Liou. Effects of Hearing Disability on the Employment Status Using WHODAS 2.0 in Taiwan. International Journal of Environmental Research and Public Health 2020, 17, 9374 .
AMA StylePin-Zhir Chao, Shih-Wei Huang, Reuben Escorpizo, Wen-Chou Chi, Chia-Feng Yen, Hua-Fang Liao, Yi-Wen Chen, Tsan-Hon Liou. Effects of Hearing Disability on the Employment Status Using WHODAS 2.0 in Taiwan. International Journal of Environmental Research and Public Health. 2020; 17 (24):9374.
Chicago/Turabian StylePin-Zhir Chao; Shih-Wei Huang; Reuben Escorpizo; Wen-Chou Chi; Chia-Feng Yen; Hua-Fang Liao; Yi-Wen Chen; Tsan-Hon Liou. 2020. "Effects of Hearing Disability on the Employment Status Using WHODAS 2.0 in Taiwan." International Journal of Environmental Research and Public Health 17, no. 24: 9374.
Developmental disability is likely to be lifelong in nature and to result in substantial activity and societal participation limitations. The performance of individuals is related to the environment, supports, and urbanization of living cities. Most of the surveys for people with disabilities have not discussed the relationship between the cognitive impairment properties and performance of participation and activities functioning, and most cognitive impairments are regarded as having similar performance. The location of residence in childhood is mainly influenced by parents and main caregivers, but the factors related to the preferences of adults with cognitive impairment in the location of residence are more complicated. Objective(s): The aim was to explore and compare the relationships of the urbanization degree of their living cities and the functioning performance of daily living in various domains among adults with intellectual disability (ID), autism, and concomitant communicative impairment (CCI). Method: The cross-sectional study was applied, and the data was collected face-to-face by professionals in all authorized hospitals in Taiwan. The participants were 5374 adults with ID (n = 4455), autism (n = 670), CCI (n = 110) and combination disabilities (n = 139) which were according to the International Statistical Classification of Diseases 9th Revision (ICD-9) from a total of 167,069 adults with disabilities from the Disability Eligibility System (DES) in Taiwan between July 2012 and October 2013. The authors used the World Health Organization Disability Assessment Schedule 2.0–36 item version of WHO (WHODAS 2.0-36 items) to measure performance and capability of daily living. Results and Conclusions: There were significant differences in age, gender, disabled severity, and the urbanization between all subgroups (p < 0.05). After adjusting the age of all participators, the degree of urbanization just significantly affected the functioning score distribution in domain 1: cognition for an adult with ID, autism, and CCI; in domain 2, mobility for an adult with CCI and combination disability; in domain 3, self-care; domain 4, independent domains for ID (p < 0.05). There were no significant differences between urbanization degree and functioning scores in all domains for adults with autism. All in all, only in groups with combination disability did we find that the worse the degree of impairment was, the lower the degree of urbanization of their place of residence was, and there was no such phenomenon in adults with autism and ID in our study.
Shyang-Woei Lin; Tzu-Ying Chiu; Tsan-Hon Liou; Chia-Feng Yen; Hui-Guan Chen. The Relationship of Urbanization and Performance of Activity and Participation Functioning among Adults with Developmental Disabilities in Taiwan. International Journal of Environmental Research and Public Health 2020, 17, 7553 .
AMA StyleShyang-Woei Lin, Tzu-Ying Chiu, Tsan-Hon Liou, Chia-Feng Yen, Hui-Guan Chen. The Relationship of Urbanization and Performance of Activity and Participation Functioning among Adults with Developmental Disabilities in Taiwan. International Journal of Environmental Research and Public Health. 2020; 17 (20):7553.
Chicago/Turabian StyleShyang-Woei Lin; Tzu-Ying Chiu; Tsan-Hon Liou; Chia-Feng Yen; Hui-Guan Chen. 2020. "The Relationship of Urbanization and Performance of Activity and Participation Functioning among Adults with Developmental Disabilities in Taiwan." International Journal of Environmental Research and Public Health 17, no. 20: 7553.
Hsiu-Ju Jen; Chia-Man Kao; Kwang-Hwa Chang; Chia-Feng Yen; Hua-Fang Liao; Wen-Chou Chi; Wen-Kuei Chung; Tsan-Hon Liou. Assessment of functioning using the WHODAS 2.0 among people with stroke in Taiwan: a 4-year follow-up study. 2020, 1 .
AMA StyleHsiu-Ju Jen, Chia-Man Kao, Kwang-Hwa Chang, Chia-Feng Yen, Hua-Fang Liao, Wen-Chou Chi, Wen-Kuei Chung, Tsan-Hon Liou. Assessment of functioning using the WHODAS 2.0 among people with stroke in Taiwan: a 4-year follow-up study. . 2020; ():1.
Chicago/Turabian StyleHsiu-Ju Jen; Chia-Man Kao; Kwang-Hwa Chang; Chia-Feng Yen; Hua-Fang Liao; Wen-Chou Chi; Wen-Kuei Chung; Tsan-Hon Liou. 2020. "Assessment of functioning using the WHODAS 2.0 among people with stroke in Taiwan: a 4-year follow-up study." , no. : 1.
To learn about the experiences of stroke recovery among young stroke survivors in Taiwan and to elucidate the beliefs, goals, and facilitators of and barriers to their recovery. A qualitative approach was used for data collection, and data were obtained from five focus groups consisting of stroke survivors aged 20–64 years (n = 25). Data were transcribed verbatim and analyzed thematically by two independent coders using NVivo version 10. “Returning to prestroke status” was a common belief of recovery for stroke survivors; their goals of recovery changed overtime from regaining physical functions, independent living, and participating in work and leisure activities to maintaining functions or returning to normality. Their perceived personal and environmental facilitators of recovery included positive attitude, family and friends, and rehabilitation, whereas barriers to recovery included psychological factors, social stigma, and physical environment. These findings provide useful insights for rehabilitation clinicians to develop culturally tailored interventions to improve poststroke recovery outcomes in young stroke survivors. Rehabilitation clinicians should understand stroke survivors’ beliefs and goals of recovery to provide tailored services. Optimizing the goal-setting process and patient–provider communication may help clinicians and survivors examine and adjust their expectations toward recovery during rehabilitation. Interventions will be needed to address personal and environmental supports and barriers, such as motivation, psychological factors, social support, and the physical environment to help survivors achieve their recovery goals.
Feng-Hang Chang; Yen-Nung Lin; Tsan-Hon Liou. Recovery after stroke: perspectives of young stroke survivors in Taiwan. Disability and Rehabilitation 2020, 1 -8.
AMA StyleFeng-Hang Chang, Yen-Nung Lin, Tsan-Hon Liou. Recovery after stroke: perspectives of young stroke survivors in Taiwan. Disability and Rehabilitation. 2020; ():1-8.
Chicago/Turabian StyleFeng-Hang Chang; Yen-Nung Lin; Tsan-Hon Liou. 2020. "Recovery after stroke: perspectives of young stroke survivors in Taiwan." Disability and Rehabilitation , no. : 1-8.
Aging and osteoarthritis (OA) are associated with a high risk of muscle mass loss, which can lead to physical disability. This study investigated the effectiveness of protein supplementation combined with exercise training (PS + ET) in improving muscle mass and functional outcomes in older adults with lower-limb OA. A comprehensive search of online databases was performed to identify randomized controlled trials (RCTs) on the effectiveness of PS + ET in older adults with hip or knee OA. Meta-analysis and risk of bias assessment of the included RCTs were conducted. Six RCTs were included in this systemic review; they had a median (range/total) Physiotherapy Evidence Database (PEDro) score of 7 (6–9) out of 10, respectively. Five RCTs that enrolled patients who underwent total joint replacement were included in this meta-analysis. The PS + ET group exhibited significant improvements in muscle mass (standard mean difference [SMD] = 1.13, p < 0.00001), pain (SMD = 1.36, p < 0.00001), and muscle strength (SMD = 0.44, p = 0.04). Our findings suggest that PS + ET improves muscle mass, muscle strength, and functional outcomes and reduces pain in older adults with lower-limb OA, particularly in those who have undergone total joint replacement.
Chun-De Liao; Yen-Tzu Wu; Jau-Yih Tsauo; Pey-Rong Chen; Yu-Kang Tu; Hung-Chou Chen; Tsan-Hon Liou. Effects of Protein Supplementation Combined with Exercise Training on Muscle Mass and Function in Older Adults with Lower-Extremity Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Trials. Nutrients 2020, 12, 2422 .
AMA StyleChun-De Liao, Yen-Tzu Wu, Jau-Yih Tsauo, Pey-Rong Chen, Yu-Kang Tu, Hung-Chou Chen, Tsan-Hon Liou. Effects of Protein Supplementation Combined with Exercise Training on Muscle Mass and Function in Older Adults with Lower-Extremity Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Trials. Nutrients. 2020; 12 (8):2422.
Chicago/Turabian StyleChun-De Liao; Yen-Tzu Wu; Jau-Yih Tsauo; Pey-Rong Chen; Yu-Kang Tu; Hung-Chou Chen; Tsan-Hon Liou. 2020. "Effects of Protein Supplementation Combined with Exercise Training on Muscle Mass and Function in Older Adults with Lower-Extremity Osteoarthritis: A Systematic Review and Meta-Analysis of Randomized Trials." Nutrients 12, no. 8: 2422.
(1) Background: Knee osteoarthritis (KOA) and aging are associated with high sarcopenia risk; sarcopenia may further affect outcomes after total knee replacement (TKR). Elastic resistance exercise training (RET) limits muscle attenuation in older adults. We aimed to identify the effects of post-TKR elastic RET on lean mass (LM) and functional outcomes in overweight and obese older women with KOA by using the brief International Classification of Functioning, Disability and Health Core Set for osteoarthritis (Brief-ICF-OA). (2) Methods: Eligible women aged ≥60 years who had received unilateral primary TKR were randomly divided into an experimental group (EG), which received postoperative RET twice weekly for 12 weeks, and a control group (CG), which received standard care. The primary and secondary outcome measures were LM and physical capacity, respectively, and were linked to the Brief-ICF-OA. The assessment time points were 2 weeks prior to surgery (T0) and postoperative at 1 month (T1; before RET) and 4 months (T2; upon completion of RET) of follow-up. An independent t test with an intention-to-treat analysis was conducted to determine the between-group differences in changes of outcome measures at T1 and T2 from T0. (3) Results: Forty patients (age: 70.9 ± 7.3 years) were randomly assigned to the EG (n = 20) or CG (n = 20). At T2, the EG exhibited significantly greater improvements in leg LM (mean difference (MD) = 0.86 kg, p = 0.004) and gait speed (MD = 0.26 m/s, p = 0.005) compared with the CG. Furthermore, the EG generally obtained significantly higher odds ratios than the CG for treatment success for most Brief-ICF-OA categories (all p < 0.001). Conclusions: Early intervention of elastic RET after TKR yielded positive postoperative outcomes based on the Brief-ICF-OA. The findings of this study may facilitate clinical decision-making regarding the optimal post-TKR rehabilitation strategy for older women with KOA.
Chun-De Liao; Yen-Shuo Chiu; Jan-Wen Ku; Shih-Wei Huang; Tsan-Hon Liou. Effects of Elastic Resistance Exercise on Postoperative Outcomes Linked to the ICF Core Sets for Osteoarthritis after Total Knee Replacement in Overweight and Obese Older Women with Sarcopenia Risk: A Randomized Controlled Trial. Journal of Clinical Medicine 2020, 9, 2194 .
AMA StyleChun-De Liao, Yen-Shuo Chiu, Jan-Wen Ku, Shih-Wei Huang, Tsan-Hon Liou. Effects of Elastic Resistance Exercise on Postoperative Outcomes Linked to the ICF Core Sets for Osteoarthritis after Total Knee Replacement in Overweight and Obese Older Women with Sarcopenia Risk: A Randomized Controlled Trial. Journal of Clinical Medicine. 2020; 9 (7):2194.
Chicago/Turabian StyleChun-De Liao; Yen-Shuo Chiu; Jan-Wen Ku; Shih-Wei Huang; Tsan-Hon Liou. 2020. "Effects of Elastic Resistance Exercise on Postoperative Outcomes Linked to the ICF Core Sets for Osteoarthritis after Total Knee Replacement in Overweight and Obese Older Women with Sarcopenia Risk: A Randomized Controlled Trial." Journal of Clinical Medicine 9, no. 7: 2194.
The progression of dementia, which impairs motor skills and cognitive function, is a warning of greater disability. The present study investigated the association between hand fine motor skills, assessed according to the Functioning Disability Evaluation Scale - Adult Version (FUNDES-Adult), and dementia severity. People with mild and moderate to severe dementia were identified from the Taiwan Data Bank of Persons with Disability. The FUNDES-Adult was assessed for all enrollees, and the following hand fine motor skills were evaluated: pen-holding, buttoning, and knotting. Statistical analysis was performed using SAS, and P values < 0.05 were considered significant. Disability in all the 3 fin. motor skills was significantly greater in patients with moderate to severe dementia than in those with mild dementia. Disability in any of the skills was sensitive to distinguish mild from moderate to severe dementia (sensitivity: 78.1%, specificity: 55.2%, area under the curve: 0.739, 95% confidence interval [CI]: 0.734-0.745). Those with fine motor skill disability were at a significantly higher risk of moderate to severe dementia (odds ratio: 3.71, 95% CI: 3.53-3.90, P < .001). Hand fine motor skill disability was more prevalent in patients with moderate to severe dementia than in patients with mild dementia. A straightforward motor skill assessment can serve as a screening tool in the community to detect the progression of dementia.
Wei-Chin Liou; Lung Chan; Chien-Tai Hong; Wen-Chou Chi; Chia-Feng Yen; Hua-Fang Liao; Jia-Hung Chen; Tsan-Hon Liou. Hand fine motor skill disability correlates with dementia severity. Archives of Gerontology and Geriatrics 2020, 90, 104168 .
AMA StyleWei-Chin Liou, Lung Chan, Chien-Tai Hong, Wen-Chou Chi, Chia-Feng Yen, Hua-Fang Liao, Jia-Hung Chen, Tsan-Hon Liou. Hand fine motor skill disability correlates with dementia severity. Archives of Gerontology and Geriatrics. 2020; 90 ():104168.
Chicago/Turabian StyleWei-Chin Liou; Lung Chan; Chien-Tai Hong; Wen-Chou Chi; Chia-Feng Yen; Hua-Fang Liao; Jia-Hung Chen; Tsan-Hon Liou. 2020. "Hand fine motor skill disability correlates with dementia severity." Archives of Gerontology and Geriatrics 90, no. : 104168.
Objective: To compare and cluster the health status and disability restrictions associated with eight major physiological functions of body systems, using functioning domains of WHO Disability Assessment Schedule 2.0. Design: Retrospective analyses of a nation-wide disability database. Setting: Population-based study. Participants: Records from patients >18 years of age with disability were obtained from the Taiwan Data Bank of Persons with Disability (July 2012–November 2017). Disability functioning profile of the following diagnosis were analyzed: stroke, schizophrenia, hearing loss, liver cirrhosis, chronic kidney disease, congestive heart failure, burn, head and neck cancer. Interventions: Not applicable. Main Outcome Measures: Demographic data, severity of impairment, and Disability Assessment Scale scores were obtained and analyzed. Radar charts were constructed using the WHO Disability Assessment Schedule 2.0. functioning domain score. Degree of similarity between any two given diagnosis was assessed by cluster analysis, comparing the Euclidean distances between radar chart data points among the six domains. Results: Based on cluster analysis of similarities between functioning domain profiles, the eight diagnoses were grouped into different disability clusters. Four clusters of disability were named according to the type restriction patterns: global-impact cluster (stroke); interaction-restriction cluster (schizophrenia, hearing loss); physical-limitation cluster, (liver cirrhosis, CKD, and congestive heart failure); and specific-impact cluster (burn, head and neck cancer). The rates of institutionalization and unemployment differed between the four clusters. Conclusion: We converted WHO Disability Assessment Schedule 2.0. functioning domain scores into six-dimensioned radar chart, and demonstrate disability restrictions can be further categorized into clusters according to similarity of functioning impairment. Understanding of disease-related disabilities provides an important basis for designing rehabilitation programs and policies on social welfare and health that reflect the daily-living needs of people according to diagnosis.
Chao-Pen Chen; Yi-Wen Chen; Kwang-Hwa Chang; Shih-Wei Huang; Chien-Hua Wu; Reuben Escorpizo; Gerold Stucki; Tsan-Hon Liou. Clustering of functioning and disability profile based on the WHO disability assessment schedule 2.0 – a nationwide databank study. Disability and Rehabilitation 2020, 1 -10.
AMA StyleChao-Pen Chen, Yi-Wen Chen, Kwang-Hwa Chang, Shih-Wei Huang, Chien-Hua Wu, Reuben Escorpizo, Gerold Stucki, Tsan-Hon Liou. Clustering of functioning and disability profile based on the WHO disability assessment schedule 2.0 – a nationwide databank study. Disability and Rehabilitation. 2020; ():1-10.
Chicago/Turabian StyleChao-Pen Chen; Yi-Wen Chen; Kwang-Hwa Chang; Shih-Wei Huang; Chien-Hua Wu; Reuben Escorpizo; Gerold Stucki; Tsan-Hon Liou. 2020. "Clustering of functioning and disability profile based on the WHO disability assessment schedule 2.0 – a nationwide databank study." Disability and Rehabilitation , no. : 1-10.
In older individuals, hand fine motor skill disability is associated with cognitive levels. Similarly, patients with moderate-to-advanced Parkinson’s disease (PD) often have cognitive dysfunction. Here, we investigated the association between hand fine motor skill and cognitive dysfunction in patients with moderate-to-advanced PD. Moderate and advanced PD patients with and without dementia were identified from the Taiwan Data Bank of Persons with Disability. Hand fine motor capacities, namely pen holding, buttoning, and knotting, were assessed with the World Health Organization Disability Assessment Schedule 2.0. Statistical analyses were performed on Statistical Analysis System (SAS) and a p value of <0.05 was considered significant. In total, 3440 patients with PD were enrolled, of which 612 had dementia, exhibiting significant disability in all three tasks. After adjustments for age, sex, and PD severity, pen holding and knotting were significantly associated with PD dementia. The presence of any disability in either task was not only sensitive to the presence of dementia but also associated with cognitive disability in moderate and advanced PD patients without dementia. In conclusion, hand fine motor skill disability was associated with cognitive disability in patients with moderate-to-advanced PD. These simple hand fine motor skills may thus be applicable in screening tests for the early identification of cognitive dysfunction in patients with moderate-to-advanced PD.
Shennie Tan; Chien Tai Hong; Jia-Hung Chen; Lung Chan; Wen-Chou Chi; Chia-Feng Yen; Hua-Fang Liao; Tsan-Hon Liou; Dean Wu. Hand Fine Motor Skill Disability Correlates with Cognition in Patients with Moderate-to-Advanced Parkinson’s Disease. Brain Sciences 2020, 10, 337 .
AMA StyleShennie Tan, Chien Tai Hong, Jia-Hung Chen, Lung Chan, Wen-Chou Chi, Chia-Feng Yen, Hua-Fang Liao, Tsan-Hon Liou, Dean Wu. Hand Fine Motor Skill Disability Correlates with Cognition in Patients with Moderate-to-Advanced Parkinson’s Disease. Brain Sciences. 2020; 10 (6):337.
Chicago/Turabian StyleShennie Tan; Chien Tai Hong; Jia-Hung Chen; Lung Chan; Wen-Chou Chi; Chia-Feng Yen; Hua-Fang Liao; Tsan-Hon Liou; Dean Wu. 2020. "Hand Fine Motor Skill Disability Correlates with Cognition in Patients with Moderate-to-Advanced Parkinson’s Disease." Brain Sciences 10, no. 6: 337.
Patients with axial spondyloarthritis (ax-SpA) present with inflammation invading the axial skeleton. Symptoms of ax-SpA interfere with patients’ quality of life, and peripheral symptoms are also noted. Human leukocyte antigen B27 was associated with adhesive capsulitis. However, epidemiological studies investigating the associated incidence and risk factors for patients with ax-SpA with adhesive capsulitis are limited. The data of patients with ax-SpA were recorded during the 2004–2008 period and followed to the end of 2010. The control cohort comprised age- and sex-matched non-ax-SpA subjects. A Cox multivariate proportional hazards model was applied to analyze the risk factors for adhesive capsulitis. The hazard ratio (HR) and adjusted hazard ratio (aHR) were estimated between the study and control cohorts after confounders were adjusted for. Effects of sulfasalazine (SSZ), methotrexate (MTX), and hydroxychloroquine (HCQ) use on adhesive capsulitis risk were also analyzed. We enrolled 2859 patients with ax-SpA in the study cohort and 11,436 control subjects. A higher incidence of adhesive capsulitis was revealed in the ax-SpA cohort: The crude HR was 1.63 (95% CI, 1.24–2.13; p < 0.001), and the aHR was 1.54 (95% CI, 1.16–2.05; p = 0.002). For patients with ax-SpA using SSZ or HCQ, no difference in aHR was noted compared with control participants, but patients with ax-SpA treated with MTX had higher HR and aHR than controls. Patients with ax-SpA are at risk for adhesive capsulitis. When these patients receive SSZ or HCQ, the risk of adhesive capsulitis can be lowered compared with that of the control cohort.
Shih-Wei Huang; Jr-Yi Wang; Che-Li Lin; Chi-Chang Huang; Tsan-Hon Liou; Hui-Wen Lin. Patients with Axial Spondyloarthritis Are at Risk of Developing Adhesive Capsulitis: Real-World Evidence Database Study in Taiwan. Journal of Clinical Medicine 2020, 9, 787 .
AMA StyleShih-Wei Huang, Jr-Yi Wang, Che-Li Lin, Chi-Chang Huang, Tsan-Hon Liou, Hui-Wen Lin. Patients with Axial Spondyloarthritis Are at Risk of Developing Adhesive Capsulitis: Real-World Evidence Database Study in Taiwan. Journal of Clinical Medicine. 2020; 9 (3):787.
Chicago/Turabian StyleShih-Wei Huang; Jr-Yi Wang; Che-Li Lin; Chi-Chang Huang; Tsan-Hon Liou; Hui-Wen Lin. 2020. "Patients with Axial Spondyloarthritis Are at Risk of Developing Adhesive Capsulitis: Real-World Evidence Database Study in Taiwan." Journal of Clinical Medicine 9, no. 3: 787.
Shih-Wei Huang; Li-Fong Lin; Kwang-Hwa Chang; Reuben Escorpizo; Tsan-Hon Liou. Development of a comprehensive core set from the international classification of functioning, disability and health for return to work among patients with stroke through delphi-based consensus. 2020, 1 .
AMA StyleShih-Wei Huang, Li-Fong Lin, Kwang-Hwa Chang, Reuben Escorpizo, Tsan-Hon Liou. Development of a comprehensive core set from the international classification of functioning, disability and health for return to work among patients with stroke through delphi-based consensus. . 2020; ():1.
Chicago/Turabian StyleShih-Wei Huang; Li-Fong Lin; Kwang-Hwa Chang; Reuben Escorpizo; Tsan-Hon Liou. 2020. "Development of a comprehensive core set from the international classification of functioning, disability and health for return to work among patients with stroke through delphi-based consensus." , no. : 1.
Background Social function and quality of life were negatively impacted by the sequelae of treatment for the disease in the head and neck cancer survivor with swallowing disorder. Method Data from a total of 1023 survivors between July 2012 and November 2017 were collected from the Taiwan Data Bank of Persons with Disability. Nonparametric rank F test was used to analyze the influence of different variables on social participation. Results (a) All WHODAS (World Health Organization Disability Assessment Schedule) 2.0 scores revealed significantly increased difficulty when swallowing impairment increased (P < .001). (b) Unemployment, institutionalization, severity of swallowing impairment, cancer sites, and WHODAS 2.0 score of domains 1 to 4 were negatively related to social participation, while living in rural area is related to increased social participation. Conclusions Social participation was negatively affected by many variables in this population. Among these variables, cancer sites and WHODAS 2.0 score of domains 1 to 4 were the strongest factors.
Yu‐Hao Lee; Shari Goo‐Yoshino; Henry L. Lew; Wen‐Chou Chi; Chia‐Feng Yen; Hua‐Fang Liao; Shih‐Ching Chen Md; Tsan‐Hon Liou Md. Social participation in head and neck cancer survivors with swallowing disorder: World Health Organization Disability Assessment Schedule 2.0 study. Head & Neck 2019, 42, 905 -912.
AMA StyleYu‐Hao Lee, Shari Goo‐Yoshino, Henry L. Lew, Wen‐Chou Chi, Chia‐Feng Yen, Hua‐Fang Liao, Shih‐Ching Chen Md, Tsan‐Hon Liou Md. Social participation in head and neck cancer survivors with swallowing disorder: World Health Organization Disability Assessment Schedule 2.0 study. Head & Neck. 2019; 42 (5):905-912.
Chicago/Turabian StyleYu‐Hao Lee; Shari Goo‐Yoshino; Henry L. Lew; Wen‐Chou Chi; Chia‐Feng Yen; Hua‐Fang Liao; Shih‐Ching Chen Md; Tsan‐Hon Liou Md. 2019. "Social participation in head and neck cancer survivors with swallowing disorder: World Health Organization Disability Assessment Schedule 2.0 study." Head & Neck 42, no. 5: 905-912.
Objective To investigate the effect of muscle strength exercise training (MSET) on lean mass (LM) gain and muscle hypertrophy in older patients with lower limb osteoarthritis (OA). Methods A comprehensive search of online databases was performed until April 20, 2019. Randomized controlled trials (RCTs) that reported the effects of MSET on LM, muscle thickness, and cross‐sectional area (CSA) in older patients with OA were identified. A risk of bias assessment and meta‐analysis were performed for the included RCTs. Results We included 19 RCTs with a median PEDro score of 6 (range: 3–7) out of 10. In total, 1195 patients (65% women, 85% with knee OA) with a mean age of 62.1 (range: 40–86) years were analyzed. MSET resulted in significantly higher LM gain (standard mean difference [SMD]: 0.49; 95% confidence interval [CI]: 0.28, 0.71; P < 0.00001) than did the nonexercise controls. Meta‐analysis results revealed significantly positive effects of MSET on muscle thickness (SMD: 0.82; 95% CI: 0.20, 1.43; P = 0.009) and CSA (SMD: 0.80; 95% CI: 0.25, 1.35; P = 0.004) compared with nonexercise controls. No significant effects in favor of MSET were observed for any muscle outcome compared with exercise controls. Five RCTs reported nonsevere adverse events in response to MSET, whereas no RCTs reported severe events. Conclusion MSET is effective in increasing LM and muscle size in older adults with OA. Clinicians should incorporate MSET into their management of patients at risk of low muscle mass to maximize health status, particularly for older individuals with OA.
Chun‐De Liao; Hung‐Chou Chen; Yu‐Chi Kuo; Jau‐Yih Tsauo; Shih‐Wei Huang; Tsan‐Hon Liou. Effects of Muscle Strength Training on Muscle Mass Gain and Hypertrophy in Older Adults With Osteoarthritis: A Systematic Review and Meta‐Analysis. Arthritis Care & Research 2019, 72, 1703 -1718.
AMA StyleChun‐De Liao, Hung‐Chou Chen, Yu‐Chi Kuo, Jau‐Yih Tsauo, Shih‐Wei Huang, Tsan‐Hon Liou. Effects of Muscle Strength Training on Muscle Mass Gain and Hypertrophy in Older Adults With Osteoarthritis: A Systematic Review and Meta‐Analysis. Arthritis Care & Research. 2019; 72 (12):1703-1718.
Chicago/Turabian StyleChun‐De Liao; Hung‐Chou Chen; Yu‐Chi Kuo; Jau‐Yih Tsauo; Shih‐Wei Huang; Tsan‐Hon Liou. 2019. "Effects of Muscle Strength Training on Muscle Mass Gain and Hypertrophy in Older Adults With Osteoarthritis: A Systematic Review and Meta‐Analysis." Arthritis Care & Research 72, no. 12: 1703-1718.