We develop a new robust control scheme for a non-holonomic spherical robot. To this end, the mathematical model of a pendulum driven non-holonomic spherical robot is first presented. Then, a recurrent neural network-based robust nonsingular sliding mode control is proposed for stabilization and tracking control of the system. The designed recurrent neural network is applied to approximate compound disturbances, including external interferences and dynamic uncertainties. Moreover, the controller is designed in a way that avoids the singularity problem in the system. Another advantage of the proposed scheme is its ability for tracking control while there exists control input saturation, which is a serious concern in robotic systems. Based on the Lyapunov theorem, the stability of the closed-loop system has also been confirmed. Lastly, the performance of the proposed control technique for the uncertain system in the presence of an external disturbance, unknown input saturation, and dynamic uncertainties has been investigated. Also, the proposed controller has been compared with a Fuzzy-PID one. Simulation results show the effectiveness and superiority of the developed control technique.