Sebastien La Vieille

Dr. Sebastien La Vieille

orcid

Research Focus & Metrics

Academic Career Length

15Years (2012-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 June 2016 in Journal of Allergy and Clinical Immunology
Verified
Journal Article
Closed access
EHElana Hochstadter
Elana Hochstadter
ACAnn Clarke
Ann Clarke
SSSarah De Schryver
Sarah De Schryver
SVSebastien La Vieille
Sebastien La Vieille
RAReza Alizadehfar
Reza Alizadehfar
MBMoshe Ben-Shoshan
Moshe Ben-Shoshan

24 February 2016 in Canadian Journal of Gastroenterology and Hepatology
Verified
Journal Article
Open access
PDF file
SVSebastien La Vieille
Sebastien La Vieille
OPOlga M. Pulido
Olga M. Pulido
MAMichael Abbott
Michael Abbott
TKTerence B. Koerner
Terence B. Koerner
SGSamuel Godefroy
Samuel Godefroy
This paper provides an overview of the latest scientific data related to the safety of uncontaminated oats (<20 ppm of gluten) in the diet of individuals with celiac disease (CD). It updates the previous Health Canada position posted on the Health Canada website in 2007 and a related paper published in 2009. It considers a number of recent studies published between January 2008 and January 2015. While recognizing that a few people with celiac disease seem to be clinically intolerant to oats, this review concludes that oats uncontaminated by gluten-containing cereals (wheat, rye, and barley) can be safely ingested by most patients with celiac disease and that there is no conclusive evidence that the consumption of uncontaminated or specially produced oats containing no greater than 20 ppm gluten by patients with celiac disease should be limited to a specific daily amount. However, individuals with CD should observe a stabilization phase before introducing uncontaminated oats to the gluten-free diet (GFD). Oats uncontaminated with gluten should only be introduced after all symptoms of celiac disease have resolved and the individual has been on a GFD for a minimum of 6 months. Long-term regular medical follow-up of these patients is recommended but this is no different recommendation to celiac individuals on a GFD without oats.

19 January 2023 in The Journal of Allergy and Clinical Immunology: In Practice
Verified
Journal Article
Closed access
SVSebastien La Vieille
Sebastien La Vieille
JHJonathan O’b. Hourihane
Jonathan O’b. Hourihane
JBJoseph L. Baumert
Joseph L. Baumert

11 May 2021 in npj Science of Food
Verified
Journal Article
Open access
PDF file
EMEmilie Manny
Emilie Manny
SVSebastien La Vieille
Sebastien La Vieille
VBVirginie Barrere
Virginie Barrere
JTJérémie Théolier
Jérémie Théolier
SGSamuel Godefroy
Samuel Godefroy
Precautionary allergen labeling (PAL) is widely used by food industries. Occurrence studies revealed that few analyzed products contained the allergen(s) present in the statement, but little is known in Canada. To improve manufacturing practices and better manage allergen cross-contamination, occurrence data is needed to determine the exposure of allergic individuals eating those products. Samples were analyzed for peanuts (n = 871) and hazelnuts (n = 863) using ELISA methods. Within samples analyzed for peanuts, 72% had a PAL (n = 628), 1% had peanuts as a minor ingredient (n = 9) and 27% were claimed “peanut-free” (n = 234). Most hazelnut samples had a PAL for tree nuts/hazelnuts (94%; n = 807) with 6% claimed “nut-free” (n = 56). Peanuts and hazelnuts were found in 4% (0.6–28.1 ppm) and 9% (0.4–2167 ppm) of all samples, respectively. Chocolates were mostly impacted; they should be treated apart from other foods and used in risk assessments scenarios to improve manufacturing practices, reducing unnecessary PAL use.

19 October 2012 in BMC Research Notes
Verified
Journal Article
Open access
PDF file
MKMegan Knoll
Megan Knoll
LSLianne Soller
Lianne Soller
MBMoshe Ben-Shoshan
Moshe Ben-Shoshan
DHDaniel Harrington
Daniel Harrington
JFJoey Fragapane
Joey Fragapane
ACAnn Clarke
Ann Clarke
Poor response rates in prevalence surveys can lead to nonresponse bias thereby compromising the validity of prevalence estimates. We conducted a telephone survey of randomly selected households to estimate the prevalence of food allergy in the 10 Canadian provinces between May 2008 and March 2009 (the SCAAALAR study: Surveying Canadians to Assess the Prevalence of Common Food Allergies and Attitudes towards Food LAbeling and Risk). A household response rate of only 34.6% was attained, and those of lower socioeconomic status, lower education and new Canadians were underrepresented. We are now attempting to target these vulnerable populations in the SPAACE study (Surveying the Prevalence of Food Allergy in All Canadian Environments) and are evaluating strategies to increase the response rate. Although the success of incentives to increase response rates has been demonstrated previously, no studies have specifically examined the use of unconditional incentives in these vulnerable populations in a telephone survey. The pilot study will compare response rates between vulnerable Canadian populations receiving and not receiving an incentive. Randomly selected households were randomly assigned to receive either a $5 incentive or no incentive. The between group differences in response rates and 95% confidence intervals (CIs) were calculated. The response rates for the incentive and non-incentive groups were 36.1% and 28.7% respectively, yielding a between group difference of 7.4% (−0.7%, 15.6%). Although the wide CI precludes definitive conclusions, our results suggest that unconditional incentives are effective in vulnerable populations for telephone surveys.

31 October 2018 in Nutrition Reviews
Verified
Journal Article
Closed access
SVSebastien La Vieille
Sebastien La Vieille
DLDavid E Lefebvre
David E Lefebvre
AKAhmad Firas Khalid
Ahmad Firas Khalid
MDMatthew R Decan
Matthew R Decan
SGSamuel Godefroy
Samuel Godefroy
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme deficiency in the world and renders those affected susceptible to potentially severe oxidative hemolysis. Although the resulting hemolysis is most often associated with drug exposure, it has also been reported after consumption of certain foods. With the exception of review articles that reiterated the historical knowledge that fava beans can provoke severe oxidative hemolysis in individuals with G6PD deficiency, very few articles have examined the safety of other food ingredients and food additives for people with G6PD deficiency. Some articles that associated specific foods with hemolysis appeared to be speculative and based on limited information. The objective of this review was to examine the association between foods, including food additives, and the triggering factors of acute hemolysis. The literature was searched for studies and case reports on food consumption and G6PD deficiency. In this review, fava beans were found to be the only food for which there is conclusive clinical evidence linking the risk of hemolytic anemia to individuals with G6PD deficiency. Food additives, at their permitted level of use in North America, can be consumed safely by most patients with G6PD deficiency.