This paper reports an experimental comparison of artificial neural network (ANN) and support vector machine (SVM) ensembles and their “nonensemble” variants for lung cancer prediction. These machine learning classifiers were trained to predict lung cancer using samples of patient nucleotides with mutations in the epidermal growth factor receptor, Kirsten rat sarcoma viral oncogene, and tumor suppressor p53 genomes collected as biomarkers from the IGDB.NSCLC corpus. The Voss DNA encoding was used to map the nucleotide sequences of mutated and normal genomes to obtain the equivalent numerical genomic sequences for training the selected classifiers. The histogram of oriented gradient (HOG) and local binary pattern (LBP) state‐of‐the‐art feature extraction schemes were applied to extract representative genomic features from the encoded sequences of nucleotides. The ANN ensemble and HOG best fit the training dataset of this study with an accuracy of 95.90% and mean square error of 0.0159. The result of the ANN ensemble and HOG genomic features is promising for automated screening and early detection of lung cancer. This will hopefully assist pathologists in administering targeted molecular therapy and offering counsel to early stage lung cancer patients and persons in at risk populations.
Although most cases are identified at a late stage, breast cancer is the most public malignancy amongst women globally. However, mammography for the analysis of breast cancer is not routinely available at all general hospitals. Prolonging the period between detection and treatment for breast cancer may raise the likelihood of proliferating the disease. To speed up the process of diagnosing breast cancer and lower the mortality rate, a computerized method based on machine learning was created. The purpose of this investigation was to enhance the investigative accuracy of machine-learning algorithms for breast cancer diagnosis. The use of machine-learning methods will allow for the classification and prediction of cancer as either benign or malignant. This investigation applies the machine learning algorithms of random forest (RF) and the support vector machine (SVM) with the feature extraction method of linear discriminant analysis (LDA) to the Wisconsin Breast Cancer Dataset. The SVM with LDA and RF with LDA yielded accuracy results of 96.4% and 95.6% respectively. This research has useful applications in the medical field, while it enhances the efficiency and precision of a diagnostic system. Evidence from this study shows that better prediction is crucial and can benefit from machine learning methods. The results of this study have validated the use of feature extraction for breast cancer prediction when compared to the existing literature.
Automatic recognition of emotion is important for facilitating seamless interactivity between a human being and intelligent robot towards the full realization of a smart society. The methods of signal processing and machine learning are widely applied to recognize human emotions based on features extracted from facial images, video files or speech signals. However, these features were not able to recognize the fear emotion with the same level of precision as other emotions. The authors propose the agglutination of prosodic and spectral features from a group of carefully selected features to realize hybrid acoustic features for improving the task of emotion recognition. Experiments were performed to test the effectiveness of the proposed features extracted from speech files of two public databases and used to train five popular ensemble learning algorithms. Results show that random decision forest ensemble learning of the proposed hybrid acoustic features is highly effective for speech emotion recognition.
Despite the recent advances in immune therapies, melanoma remains one of the deadliest and most difficult skin cancers to treat. Literature reports that multifarious driver oncogenes with tumor suppressor genes are responsible for melanoma progression and its complexity can be demonstrated by alterations in expression with signaling cascades. However, a further improvement in the therapeutic outcomes of the disease is highly anticipated with the aid of humanoid assistive technologies that are nowadays touted as a superlative alternative for the clinical diagnosis of diseases. The development of the projected technology-assistive diagnostics will be based on the innovations of medical imaging, artificial intelligence, and humanoid robots. Segmentation of skin lesions in dermoscopic images is an important requisite component of such a breakthrough innovation for an accurate melanoma diagnosis. However, most of the existing segmentation methods tend to perform poorly on dermoscopic images with undesirable heterogeneous properties. Novel image segmentation methods are aimed to address these undesirable heterogeneous properties of skin lesions with the help of image preprocessing methods. Nevertheless, these methods come with the extra cost of computational complexity and their performances are highly dependent on the preprocessing methods used to alleviate the deteriorating effects of the inherent artifacts. The overarching objective of this study is to investigate the effects of image preprocessing on the performance of a saliency segmentation method for skin lesions. The resulting method from the collaboration of color histogram clustering with Otsu thresholding is applied to demonstrate that preprocessing can be abolished in the saliency segmentation of skin lesions in dermoscopic images with heterogeneous properties. The color histogram clustering is used to automatically determine the initial clusters that represent homogenous regions in an input image. Subsequently, a saliency map is computed by agglutinating color contrast, contrast ratio, spatial feature, and central prior to efficiently detect regions of skin lesions in dermoscopic images. The final stage of the segmentation process is accomplished by applying Otsu thresholding followed by morphological analysis to obliterate the undesirable artifacts that may be present at the saliency detection stage. Extensive experiments were conducted on the available benchmarking datasets to validate the performance of the segmentation method. Experimental results generally indicate that it is passable to segment skin lesions in dermoscopic images without preprocessing because the applied segmentation method is ferociously competitive with each of the numerous leading supervised and unsupervised segmentation methods investigated in this study.
13 February 2018 in Mathematical Problems in Engineering
The prevalence of melanoma skin cancer disease is rapidly increasing as recorded death cases of its patients continue to annually escalate. Reliable segmentation of skin lesion is one essential requirement of an efficient noninvasive computer aided diagnosis tool for accelerating the identification process of melanoma. This paper presents a new algorithm based on perceptual color difference saliency along with binary morphological analysis for segmentation of melanoma skin lesion in dermoscopic images. The new algorithm is compared with existing image segmentation algorithms on benchmark dermoscopic images acquired from public corpora. Results of both qualitative and quantitative evaluations of the new algorithm are encouraging as the algorithm performs excellently in comparison with the existing image segmentation algorithms.
The conventional dermatology practice of performing noninvasive screening tests to detect skin diseases is a source of escapable diagnostic inaccuracies. Literature suggests that automated diagnosis is essential for improving diagnostic accuracies in medical fields such as dermatology, mammography, and colonography. Classification is an essential component of an assisted automation process that is rapidly gaining attention in the discipline of artificial intelligence for successful diagnosis, treatment, and recovery of patients. However, classifying skin lesions into multiple classes is challenging for most machine learning algorithms, especially for extremely imbalanced training datasets. This study proposes a novel ensemble deep learning algorithm based on the residual network with the next dimension and the dual path network with confidence preservation to improve the classification performance of skin lesions. The distributed computing paradigm was applied in the proposed algorithm to speed up the inference process by a factor of 0.25 for a faster classification of skin lesions. The algorithm was experimentally compared with 16 deep learning and 12 ensemble deep learning algorithms to establish its discriminating prowess. The experimental comparison was based on dermoscopic images congregated from the publicly available international skin imaging collaboration databases. We propitiously recorded up to 82.52% average sensitivity, 99.00% average specificity, 98.54% average balanced accuracy, and 92.84% multiclass accuracy without prior segmentation of skin lesions to outstrip numerous state-of-the-art deep learning algorithms investigated.