Gail Besner

Dr. Gail Besner

orcid

Research Focus & Metrics

Academic Career Length

22Years (2005-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 June 2016 in Journal of Pediatric Surgery
Verified
Journal Article
Closed access
TRTerrence M. Rager
Terrence M. Rager
JOJacob K. Olson
Jacob K. Olson
YZYu Zhou
Yu Zhou
YWYijie Wang
Yijie Wang
GBGail Besner
Gail Besner

1 January 2020 in Journal of Pediatric Surgery
Verified
Journal Article
Closed access
CPCourtney Pisano
Courtney Pisano
JGJeffrey Galley
Jeffrey Galley
MEMostafa Elbahrawy
Mostafa Elbahrawy
YWYijie Wang
Yijie Wang
AFAidan Farrell
Aidan Farrell
GBGail Besner
Gail Besner

11 March 2020 in Nutrients
Verified
Journal Article
Open access
PDF file
JGJeffrey Galley
Jeffrey Galley
GBGail Besner
Gail Besner
In the past few decades, interest in the therapeutic benefits of exosomes and extracellular vesicles (EVs) has grown exponentially. Exosomes/EVs are small particles which are produced and exocytosed by cells throughout the body. They are loaded with active regulatory and stimulatory molecules from the parent cell including miRNAs and enzymes, making them prime targets in therapeutics and diagnostics. Breast milk, known for years to have beneficial health effects, contains a population of EVs which may mediate its therapeutic effects. This review offers an update on the therapeutic potential of exosomes/EVs in disease, with a focus on EVs present in human breast milk and their remedial effect in the gastrointestinal disease necrotizing enterocolitis. Additionally, the relationship between EV miRNAs, health, and disease will be examined, along with the potential for EVs and their miRNAs to be engineered for targeted treatments.

1 June 2018 in Journal of Pediatric Surgery
Verified
Journal Article
Closed access
CMChristopher J. McCulloh
Christopher J. McCulloh
JOJacob K. Olson
Jacob K. Olson
YWYijie Wang
Yijie Wang
YZYu Zhou
Yu Zhou
NTNatalie Huibregtse Tengberg
Natalie Huibregtse Tengberg
GBGail Besner
Gail Besner

1 May 2013 in Seminars in Pediatric Surgery
Verified
Journal Article
Closed access
DWDaniel J. Watkins
Daniel J. Watkins
GBGail Besner
Gail Besner