Name: Kwan-Sik MIN. Educational background: PhD, University of Tokyo; Postdoc., Uni. of Iowa, Dept. of Pharmacology; Visiting Professor, UC Davis. Work experience: Since 2002, I have been working in the Department of Animal Life Science at Hankyong National University. My primary research focuses on the function of glycans in glycoprotein hormones, specifically eCG, FSH, and LH. By producing recombinant forms of these hormones, I have investigated how specific glycans influence their biological activity. Notably, N-linked glycosylation plays a crucial functional role in major biological activities, while O-linked glycosylation at the C-terminal of eCG beta has been found to be associated with secretion and delayed in vivo activity. Additionally, my research includes the functional analysis of naturally occurring inactivation and activation variants in glycoprotein receptors belonging to Class A GPCRs. These studies have been conducted extensively not only in mammals, including horses, but also in fish species such as eels. Recently, I have published research papers on the signaling mechanisms of these GPCRs, specifically analyzing the functional roles of glycosylation sites in these receptors. My studies focus on biased signaling related to cAMP and β-arrestin pathways.