Jesús Manuel De Aldecoa Castillo

Mr. Jesús Manuel De Aldecoa Castillo

orcid

Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
10 March 2020 in Children
Verified
Journal Article
Open access
PDF file
JCJesús Manuel De Aldecoa Castillo
Jesús Manuel De Aldecoa Castillo
TFTamara Daniela Frydman
Tamara Daniela Frydman
JRJosé de Jesús Reséndiz-Rojas
José de Jesús Reséndiz-Rojas
ATAlejandro Trejo
Alejandro Trejo
JCJesús Manuel De Aldecoa Castillo
Jesús Manuel De Aldecoa Castillo
Predictive formulas to estimate body composition in children have been explored for some time, to this date, the most accurate obesity diagnostic tool is to determine fat mass. The aim of this study is to establish cutoff points that allow for a precise interpretation of nutritional status using the Fat Mass Index (FMI) in a Mexican pediatric population. A literature review using PubMed and Cochrane databases was made, searching for research articles on childhood obesity that compared BMI, FM percentage, and FMI, as well as those proposing diagnostic cutoff points. Mathematic formulas and linear regressions were then used to make a proposal on accurate cutoff points for this population. Our findings show that FM percentage is less precise than BMI and FMI in diagnosing obesity, and FMI seems to be a more complete tool for assessment as it differentiates fat and muscle mass of the total body weight. Both BMI and FMI should be considered when clinical evaluations regarding weight, with BMI complementing FMI by establishing fat-free mass. Our proposed cutoff points need to be validated in this population.

7 January 2025 in Medicina
Verified
Journal Article
Open access
PDF file
MAMelchor Alpizar
Melchor Alpizar
SSamantha Estefania Olguín Reyes
Samantha Estefania Olguín Reyes
AEAndrea Medina Estévez
Andrea Medina Estévez
JLJulieta Alejandra Saturno Lobos
Julieta Alejandra Saturno Lobos
JCJesús Manuel De Aldecoa Castillo
Jesús Manuel De Aldecoa Castillo
DSDulce María Fernanda Alpízar Sánchez
Dulce María Fernanda Alpízar Sánchez
Introduction: Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) stems from disrupted lipid metabolism in the liver, often linked to obesity, type 2 diabetes, and dyslipidemia. In Mexico, where obesity affects 36.9% of adults, MASLD prevalence has risen, especially with metabolic syndrome affecting 56.31% by 2018. MASLD can progress to Metabolic Dysfunction-Associated Steatohepatitis (MASH), affecting 5.27% globally, leading to severe complications like cirrhosis and hepatocellular carcinoma. Background: Visceral fat distribution varies by gender, impacting MASLD development due to hormonal influences. Insulin resistance plays a central role in MASLD pathogenesis, exacerbated by high-fat diets and specific fatty acids, leading to hepatic steatosis. Lipotoxicity from saturated fatty acids further damages hepatocytes, triggering inflammation and fibrosis progression in MASH. Diagnosing MASLD traditionally involves invasive liver biopsy, but non-invasive methods like ultrasound and transient elastography are preferred due to their safety and availability. These methods detect liver steatosis and fibrosis with reasonable accuracy, offering alternatives to biopsy despite varying sensitivity and specificity. Conclusions: MASLD as a metabolic disorder underscores its impact on public health, necessitating improved awareness and early management strategies to mitigate its progression to severe liver diseases.

20 February 2020 in Case Reports in Clinical Nutrition
Verified
Journal Article
Open access
JCJesús Manuel De Aldecoa Castillo
Jesús Manuel De Aldecoa Castillo
TFTamara Daniela Frydman
Tamara Daniela Frydman
DRDaniela Rubio-Mendoza
Daniela Rubio-Mendoza
CACarlos Alvarado-Vargas
Carlos Alvarado-Vargas
MAMelchor Alpizar
Melchor Alpizar
Postoperative patients of intestinal reconnection in Morelia, Mexico, are usually in for 3–5 days of oral fast, which increases protein catabolism in the patient, thus lengthening their hospital stay and increasing the risk of developing metabolic comorbidities. Hypocaloric peripheral parenteral nutrition (HPPN) reduces proteolysis and improves inflammatory markers in these patients. The aim of this case report is to determine whether or not peripheral parenteral nutrition (PPN) improves inflammation, lessening the postoperative risk. A 62-year-old female patient and her cancer diagnosis and intestinal reconnection surgery are discussed. PPN is not commonly used in this type of patients due to the short duration of the fast, although its use is common before surgery. However, postoperative use can be beneficial as well, and given the delicate postoperative state these patients are in, it is worth it (at least in these cases) to give them all the strength and tools available for a better recovery. PPN in the case discussed herein improved the patient’s inflammatory marker levels in a shorter period.