Cheng Lei

Dr. Cheng Lei

orcid

Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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7 November 2019 in PLOS ONE
Verified
Journal Article
Open access
PDF file
CLCheng Lei
Cheng Lei
KSKejimu Sunzi
Kejimu Sunzi
FDFengling Dai
Fengling Dai
XLXiaoqin Liu
Xiaoqin Liu
YWYanfen Wang
Yanfen Wang
MJMei Ju
Mei Ju
In recent years, virtual reality (VR) has been tested as a therapeutic tool in neurorehabilitation research. However, the impact effectiveness of VR technology on for Parkinson’s Disease (PD) patients is still remains controversial unclear. In order to provide a more scientific basis for rehabilitation of PD patients’ modality, we conducted a systematic review of VR rehabilitation training for PD patients and focused on the improvement of gait and balance. An comprehensive search was conducted using the following databases: PubMed, Web of Science, Cochrane Library, CINHAL, Embase and CNKI (China National Knowledge Infrastructure).Articles published before 30 December 2018 and of a randomized controlled trial design to study the effects of VR for patients with PD were included. The study data were pooled and a meta-analysis was completed. This systematic review was conducted in accordance with the PRISMA guideline statement and was registered in the PROSPERO database (CRD42018110264). A total of sixteen articles involving 555 participants with PD were included in our analysis. VR rehabilitation training performed better than conventional or traditional rehabilitation training in three aspects: step and stride length (SMD = 0.72, 95%CI = 0.40,1.04, Z = 4.38, P<0.01), balance function (SMD = 0.22, 95%CI = 0.01,0.42, Z = 2.09, P = 0.037), and mobility(MD = -1.95, 95%CI = -2.81,-1.08, Z = 4.41, P<0.01). There was no effect on the dynamic gait index (SMD = -0.15, 95%CI = -0.50,0.19, Z = 0.86, P = 0.387), and gait speed (SMD = 0.19, 95%CI = -0.03,0.40, Z = 1.71, P = 0.088).As for the secondary outcomes, compared with the control group, VR rehabilitation training demonstrated more significant effects on the improvement of quality of life (SMD = -0.47, 95%CI = -0.73,-0.22, Z = 3.64, P<0.01), level of confidence (SMD = -0.73, 95%CI = -1.43,-0.03, Z = 2.05, P = 0.040), and neuropsychiatric symptoms (SMD = -0.96, 95%CI = -1.27,-0.65, Z = 6.07, P<0.01), while it may have similar effects on global motor function (SMD = -0.50, 95%CI = -1.48,0.48, Z = 0.99, P = 0.32), activities of daily living (SMD = 0.25, 95%CI = -0.14,0.64, Z = 1.24, P = 0.216), and cognitive function (SMD = 0.21, 95%CI = -0.28,0.69, Z = 0.84, P = 0.399).During the included interventions, four patients developed mild dizziness and one patient developed severe dizziness and vomiting. According to the results of this study, we found that VR rehabilitation training can not only achieve the same effect as conventional rehabilitation training. Moreover, it has better performance on gait and balance in patients with PD. Taken together, when the effect of traditional rehabilitation training on gait and balance of PD patients is not good enough, we believe that VR rehabilitation training can at least be used as an alternative therapy. More rigorous design of large-sample, multicenter randomized controlled trials are needed to provide a stronger evidence-based basis for verifying its potential advantages.

20 June 2024 in International Journal of Surgery
Verified
Journal Article
Open access
HYHongfan Yu
Hongfan Yu
CLCheng Lei
Cheng Lei
XWXing Wei
Xing Wei
YWYaqin Wang
Yaqin Wang
WXWei Xu
Wei Xu
QSQiuling Shi
Qiuling Shi
Background: Electronic symptom monitoring via patient-reported outcomes in surgical oncology is limited owing to lengthy instruments and non-specific items in common patient-reported outcome instruments. To establish electronic symptom monitoring through a clinically relevant and fit-for-purpose core set of patient-reported outcome in patients undergoing lung cancer surgery. Materials and methods: One qualitative (Cohort 1) and two prospective studies (Cohorts 2 and 3) were conducted between 2018 and 2022. Patients undergoing lung cancer surgery were recruited. Items of symptoms and daily functioning were generated through extensive interviews in Cohort 1 and incorporated into a smartphone-based platform to establish the electronic Perioperative Symptom Assessment for Lung surgery (ePSA-Lung). This instrument was finalized and validated in Cohort 2. Patients in Cohort 3 were longitudinally monitored for the first-year post-surgery using the validated ePSA-Lung. Results: In total, 1037 patients scheduled for lung cancer surgery were recruited. The 11-item draft PSA-Lung was generated based on qualitative interview with 39 patients and input from a Delphi study involving 42 experts. A 9-item ePSA-Lung was finalized by assessing 223 patients in the validation cohort; the results supported the instrument’s understandability, reliability, sensitivity, and surgical specificity. In Cohort 3 (n=775), compliance ranged from 63.21 to 84.76% during the 1-year follow-up after discharge. Coughing, shortness of breath, and disturbed sleep were the most severe symptoms after discharge. Longitudinally, patients who underwent single-port video-assisted thoracic surgery had a lower symptom burden than those who underwent multi-port video-assisted thoracic surgery or thoracotomy (all symptoms, P<0.001). Conclusions: The ePSA-Lung is valid, concise, and clinically applicable as it supports electronic symptom monitoring in surgical oncology care. The need for long-term extensive care was identified for patients after discharge, even in early-stage cancer with potential curative treatment.

3 October 2023 in Cancer Medicine
Verified
Journal Article
Open access
CLCheng Lei
Cheng Lei
RGRuoyan Gong
Ruoyan Gong
JZJiayuan Zhang
Jiayuan Zhang
KSKejimu Sunzi
Kejimu Sunzi
NXNa Xu
Na Xu
QSQiuling Shi
Qiuling Shi
Background: Patients with lung cancer surgery often suffer pain after discharge. However, there is limited evidence to describe the pain experience from the qualitative investigation. This study was designed to describe the pain experience of lung cancer patients during home recovery after surgery and to provide evidence for developing pain management strategies.Methods: This qualitative descriptive study recruited 35 patients who had received lung resection and were discharged by purposive sampling from May to July 2022. Mobile phone interviews were conducted to collect views on patients' pain experience after discharge. The interviews were audio‐recorded and converted verbatim into standard text, and the data were iteratively thematic analyzed.Results: A thematic framework was identified for three themes: perception and impact of pain, coping styles for pain, and unmet needs for pain. Whether short or long‐term after discharge, patients complain that they suffer from different degrees and types of pain, causing them a “double burden” physically and mentally. The lack of knowledge about pain may lead them to adopt very different coping styles and desire professional continuous pain management.Conclusions: This study may help clarify the status of pain problems that patients face after lung cancer surgery and provides multiple dimensions of pain assessment and management objectives for quantitative research. We call on medical staff to pay attention to patients' perspectives and related needs after discharge and formulate targeted management strategies to reduce pain and improve their quality of life.

2 July 2025 in Frontiers in Psychiatry
Verified
Journal Article
Open access
PDF file
KSKejimu Sunzi
Kejimu Sunzi
HLHui Luo
Hui Luo
LYLina Yin
Lina Yin
YLYadi Li
Yadi Li
XZXin Zhou
Xin Zhou
CLCheng Lei
Cheng Lei
Background: Rapid global population ageing has significantly increased the number of older adults requiring institutional care. In nursing homes, older residents frequently experience reduced autonomy, diminished social status, and restricted opportunities for meaningful social engagement, all of which can severely threaten their sense of dignity. Although dignity is widely acknowledged as a fundamental human right and is critical for maintaining older adults’ psychological well-being and overall quality of life, limited attention has been paid to understanding how Chinese nursing-home residents perceive, experience, and preserve their dignity. Clarifying these dignity-related experiences is essential to inform interventions and policies aimed at improving care practices and enhancing residents’ quality of life.Aim: To address the limited qualitative evidence on dignity in Chinese nursing homes, this study explored residents’ perceptions of dignity, the factors that undermine or enhance it, and the strategies they employ to preserve it.Methods: We adopted a descriptive phenomenological design to explore nursing-home residents’ perspectives and lived experiences regarding dignity. Between June and December 2023, we conducted semi-structured interviews with 35 nursing-home residents in western China (aged 65–92 years; length of stay 1 to > 7 years). Purposive maximum-variation sampling captured diversity in age, gender, functional status, and socioeconomic background. All interviews were audio-recorded, transcribed verbatim, and thematically analyzed using Colaizzi’s phenomenological procedure. Reporting adhered to SRQR guidelines.Results: The following four themes were identified: Older people’s perception of dignity, The influence of dignity on the older people, Factors affecting the promotion of dignity, Dignity maintenance strategies for the older people.Conclusion: Dignity in nursing-home settings is deeply influenced by physical dependence, the quality of staff–resident interactions, and the availability of meaningful social engagement. When dignity is preserved, residents display better psychosocial adjustment; when violated, they experience significant emotional distress.Recommendations: Nursing homes should implement staff training in person-centered, respect-focused care; design routines that maximize privacy and autonomy; and expand social and recreational programs. Future studies should develop and test targeted dignity-enhancement interventions and include family perspectives to create holistic, dignity-oriented care models.

1 January 2024 in Cancer Medicine
Verified
Journal Article
Open access
XZXiangxi Zhou
Xiangxi Zhou
CLCheng Lei
Cheng Lei
XWXing Wei
Xing Wei
WDWei Dai
Wei Dai
WXWei Xu
Wei Xu
QSQiuling Shi
Qiuling Shi
Purpose: Cough is one of the most common symptoms after lung cancer surgery, which seriously affects the quality of life. Little research has been conducted on patient's experiences of cough following lung surgery. This study aimed to elucidate the experience of coughing after lung cancer surgery from the patient's perspective regarding symptoms and their impacts on daily life, as well as triggers and dealing strategies.Methods: Between June 2023 and July 2023, we conducted semi‐structured interviews with patients from outpatient clinics of two hospitals who were pathologically diagnosed with lung cancer and experienced cough after surgery through convenience sampling. The interview recordings were transcribed and analyzed by two researchers. The traditional content analysis and thematic analysis were used to identify the common codes, subthemes, and themes.Results: A total of 28 participants were interviewed. The mean age of the participants was 55.21 years (range: 36–75 years), and 21 participants were female. Most patients (75%) were interviewed within 6 months of surgery. We identified five themes (accompanying symptoms, incentives, effects, solution, and information sources) and 12 subthemes (local symptoms, systemic symptoms, personal factors, external factors, emotion, relationship with others, reduced quality of life, medical measures, nonmedical measures, no measures, relatives and friends, and the Internet). Patients with lung cancer may experience various cough symptoms after surgery, which a variety of internal and external factors can trigger. The coughing imposes a double burden on the physical and psychological due to the negative emotions it provokes.Conclusion: We generated a concept framework of cough after lung cancer surgery, providing a basis for further development of measurement tools from the patients' perspective. The lack of knowledge related to coughing highlights the need for adequate and timely health education and professional medical care.

31 October 2020 in BMJ Open
Verified
Journal Article
Open access
PDF file
YWYuxuan Wu
Yuxuan Wu
CLCheng Lei
Cheng Lei
ZHZhimin Huangfu
Zhimin Huangfu
KSKejimu Sunzi
Kejimu Sunzi
CYChangmei Yang
Changmei Yang
Introduction Backward walking (BW) is otherwise known as retrowalking. As opposed to forward walking, BW is a countersequential exercise and is a common method of rehabilitation training and disease-assisted treatment. Studies have shown that BW has a helpful effect on improving lower limb proprioception, gait synergy and improving limb balance. Many studies have concluded that BW can improve the symptoms of patients with knee osteoarthritis (KOA) and can be used for rehabilitation and adjunctive treatment of KOA, but there is a lack of evidence-based medical evidence.This research aims to provide an update to the most recent available evidence on the effect of BW on patients with KOA . Methods and analyses Electronic databases, such as Ovid/MEDLINE, EMBASE, CINAHL, Scopus, Web of Science and PubMed, will be searched by us. We will include studies identified from citation until 12 May 2020 and will not be restricted by geographical setting. The search will not be limited to the language of the publication, but the study of human subjects. Randomised controlled trials (RCTs) on the BW training of KOA will be included, with outcome measures including pain, knee function or balance function. The quality of included RCTs will be evaluated according to the Cochrane Collaboration’s risk of bias tool. A meta-analysis or systematic review will be performed to summarise the effects of BW training. We will perform sensitivity analysis on the sample size of RCTs, meta-regression analysis of the follow-up periods, dosages and baselines of outcome measures, and publication bias analysis. Ethics and dissemination Ethical approval is not required as this study will not involve confidential personal data. The results of this study will be disseminated through a peer-reviewed journal. PROSPERO registration number CRD42020185694.