This study presents a sediment rating curve (SRC), multiple regression (MR), and long short-term memory (LSTM) model for estimating daily suspended sediment concentration (SSC). The data of daily SSC at Yen Thuong and daily flow at five locations in the Ca River Basin, Vietnam are used to demonstrate multiple approaches. Using the daily flow and SSC data in the period from 2009 to 2019, appropriate coefficients in each method are identified carefully using five popular criteria. The results showed that SRC and MR approaches reproduced acceptably the observed values, with the values of RMSE, MAE, and ME of daily SSC being less than 5% of daily SSC magnitude observed at the station, while NSE ranges from 0.47 to 0.63 and r coefficient varies between 0.69 and 0.80. The LSTM model represented the observed values of daily SSC very well. The values of two dimensionless criteria are greater than 0.94 and its values of three-dimensional criteria are smaller than 2.0% of the observed magnitude of daily SSC in both training and validation steps. The LSTM model is found to be the best among the three investigated approaches. Then, the model is applied to estimate daily SSC values for the period from 1969 to 2008 and the year 2020.