Hazem Shaheen

Prof. Hazem Shaheen

Professor of Veterinary Pharmacology and Therapeutics
orcid

Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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Gaber El-Saber BatihaGaber El-Saber Batiha
Gaber El-Saber Batiha
AAAli Alqahtani
Ali Alqahtani
Oluwafemi Adeleke OjoOluwafemi Adeleke Ojo
Oluwafemi Adeleke Ojo
Hazem ShaheenHazem Shaheen
Hazem Shaheen
LWLamiaa Wasef
Lamiaa Wasef
Helal HettaHelal Hetta
Helal Hetta
Pepper originated from the Capsicum genus, which is recognized as one of the most predominant and globally distributed genera of the Solanaceae family. It is a diverse genus, consisting of more than 31 different species including five domesticated species, Capsicum baccatum, C. annuum, C. pubescen, C. frutescens, and C. chinense. Pepper is the most widely used spice in the world and is highly valued due to its pungency and unique flavor. Pepper is a good source of provitamin A; vitamins E and C; carotenoids; and phenolic compounds such as capsaicinoids, luteolin, and quercetin. All of these compounds are associated with their antioxidant as well as other biological activities. Interestingly, Capsicum fruits have been used as food additives in the treatment of toothache, parasitic infections, coughs, wound healing, sore throat, and rheumatism. Moreover, it possesses antimicrobial, antiseptic, anticancer, counterirritant, appetite stimulator, antioxidant, and immunomodulator activities. Capsaicin and Capsicum creams are accessible in numerous ways and have been utilized in HIV-linked neuropathy and intractable pain.

11 February 2023 in Naunyn-Schmiedeberg's Archives of Pharmacology
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Gaber El-Saber BatihaGaber El-Saber Batiha
Gaber El-Saber Batiha
John Oluwafemi TeiboJohn Oluwafemi Teibo
John Oluwafemi Teibo
LWLamiaa Wasef
Lamiaa Wasef
Hazem ShaheenHazem Shaheen
Hazem Shaheen
Ayomide Peter AkomolafeAyomide Peter Akomolafe
Ayomide Peter Akomolafe
MPMarios Papadakis
Marios Papadakis
Lavandula species is a flowering plant that is common in Europe and across the Mediterranean. Lavender has many health benefits for humans. In addition to its use in herbal medicine, it is widely used in the fields of cosmetics, perfumes, foods, and aromatherapy. Google Scholar, PubMed, Scopus, and Web of Science were used to search for relevant material on the phytochemical ingredients, the pharmacologic effects of the ingredients, and the mechanism of action of the Lavandula species identified. These materials were reviewed in order to have access to important updates about the Lavandula species. Lavender as referred to in English contains essential oils, anthocyanins, phytosterols, sugars, minerals, coumaric acid, glycolic acid, valeric acid, ursolic acid, herniarins, coumarins, and tannins. It has been used to treat colic and chest ailments, worrisome headaches, and biliousness, and in cleaning wounds. It has antifungal, antibacterial, neurologic, antimicrobial, anti-parasitic, anti-diabetic, and analgesic effects among others. Lavandula species has prospects for various biological applications, especially with its dermatological application. Advances in drug development would enable characterization of various bioactive constituents; thus, its development and application can have a more positive impact on humanity. Here, we highlighted updated information on the history, distribution, traditional uses, phytochemical components, pharmacology, and various biological activities of Lavandula species.

18 November 2022 in Naunyn-Schmiedeberg's Archives of Pharmacology
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Journal Article
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Gaber El-Saber BatihaGaber El-Saber Batiha
Gaber El-Saber Batiha
LWLamiaa Wasef
Lamiaa Wasef
John Oluwafemi TeiboJohn Oluwafemi Teibo
John Oluwafemi Teibo
Hazem ShaheenHazem Shaheen
Hazem Shaheen
Ali Muhammad ZakariyaAli Muhammad Zakariya
Ali Muhammad Zakariya
MPMarios Papadakis
Marios Papadakis
Medicinal plants have a long track record of use in history, and one of them is Commiphora myrrh which is commonly found in the southern part of Arabia, the northeastern part of Africa, in Somalia, and Kenya. Relevant literatures were accessed via Google Scholar, PubMed, Scopus, and Web of Science to give updated information on the phytochemical constituents and pharmacological action of Commiphora myrrh. It has been used traditionally for treating wounds, mouth ulcers, aches, fractures, stomach disorders, microbial infections, and inflammatory diseases. It is used as an antiseptic, astringent, anthelmintic, carminative, emmenagogue, and as an expectorant. Phytochemical studies have shown that it contains terpenoids (monoterpenoids, sesquiterpenoids, and volatile/essential oil), diterpenoids, triterpenoids, and steroids. Its essential oil has applications in cosmetics, aromatherapy, and perfumery. Research has shown that it exerts various biological activities such as anti-inflammatory, antioxidant, anti-microbial, neuroprotective, anti-diabetic, anti-cancer, analgesic, anti-parasitic, and recently, it was found to work against respiratory infections like COVID-19. With the advancement in drug development, hopefully, its rich phytochemical components can be explored for drug development as an insecticide due to its great anti-parasitic activity. Also, its interactions with drugs can be fully elucidated.This review highlights an updated information on the history, distribution, traditional uses, phytochemical components, pharmacology, and various biological activities of Commiphora myrrh. Graphical abstract Graphical summary of the phytochemical and pharmacological update of Commiphora myrrh

6 March 2023 in Naunyn-Schmiedeberg's Archives of Pharmacology
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Gaber El-Saber BatihaGaber El-Saber Batiha
Gaber El-Saber Batiha
AAAli Esmail Al-Snafi
Ali Esmail Al-Snafi
MTMahdi M. Thuwaini
Mahdi M. Thuwaini
John Oluwafemi TeiboJohn Oluwafemi Teibo
John Oluwafemi Teibo
Hazem ShaheenHazem Shaheen
Hazem Shaheen
MPMarios Papadakis
Marios Papadakis
Morusalba is a fast-growing shrub or medium-sized tree with a straight, cylindrical trunk. Medicinally, whole plants, leaves, fruits, branches, and roots have been employed. Google Scholar, PubMed, Scopus, and Web of Science were used to search for relevant material on the phytochemical components and pharmacologic and mechanism of action of the Morus alba. This was reviewed to assess important updates about Morus alba. The fruits of Morus alba have traditionally been used as an analgesic, anthelmintic, antibacterial, anti-rheumatic, diuretic, hypotensive, hypoglycemia, purgative, restorative, sedative tonic, and blood stimulant. Various plant parts were used as a cooling, sedating, diuretic, tonic, and astringent agent to treat nerve disorders. The plant contained tannins, steroids, phytosterols, sitosterol, glycosides, alkaloids, carbohydrates, proteins, and amino acids, as well as saponins, triterpenes, phenolics, flavonoids, benzofuran derivatives, anthocyanins, anthraquinones, glycosides, vitamins, and minerals. Previous pharmacological research identified antimicrobial, anti-inflammatory, immunological, analgesic, antipyretic, antioxidant, anti-cancer, antidiabetic, gastrointestinal, respiratory, cardiovascular, hypolipidemic, anti-obesity, dermatological, neurological, muscular, and protecting effects. This study looked at Morus alba’s traditional uses, chemical components, and pharmacological effects.

9 March 2020 in Animals
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Mohamed E.  Abd El-HackMohamed E. Abd El-Hack
Mohamed E. Abd El-Hack
Mahmoud AlagawanyMahmoud Alagawany
Mahmoud Alagawany
Hazem ShaheenHazem Shaheen
Hazem Shaheen
DSdalia samak
dalia samak
SOSarah I. Othman
Sarah I. Othman
MSMahmoud Sitohy
Mahmoud Sitohy
Poultry enterprises have sustained rapid development through the last three decennaries. For which reason, higher utilization of antibacterial, either as therapeutic or growth promoting agents, has been accepted. Owing to the concern of developing bacterial resistance among populations towards antibiotic generations, accumulation of antibacterial remaining’s in chicken products and elevating shopper request for outcomes without antibacterial remaining’s, looking for unconventional solutions that could exchange antibacterial without influencing productiveness or product characters. Using natural alternatives including ginger, garlic prebiotics, organic acids, plant extracts, etheric oils and immune stimulants have been applied to advance the performance, hold poultry productiveness, prevent and control the enteric pathogens and minimize the antibacterial utilization in the poultry production in recent years. The use of a single replacement or ideal assemblage of different choices besides good supervision and livestock welfare may play a basic role in maximizing benefits and preserving poultry productiveness. The object of this review was to support an outline of the recent knowledge on the use of the natural replacements (ginger and its derivatives) in poultry feed as feed additives and their effects on poultry performance, egg and meat quality, health as well as the economic efficiency.

28 October 2022 in Molecules
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Gaber El-Saber BatihaGaber El-Saber Batiha
Gaber El-Saber Batiha
NANosheen Akhtar
Nosheen Akhtar
AAAbdulrahman Alsayegh
Abdulrahman Alsayegh
WAWafaa Fouzi Abusudah
Wafaa Fouzi Abusudah
NANajlaa Hamed Almohmadi
Najlaa Hamed Almohmadi
Michel De WaardMichel De Waard
Michel De Waard
Plants are a promising source of bioactive compounds that can be used to tackle many emerging diseases both infectious and non-infectious. Among different plants, Acacia is a very large genus and exhibits a diverse array of bioactive agents with remarkable pharmacological properties against different diseases. Acacia, a herb found all over the world, contains approximately more than 1200 species of the Fabaceae family. In the present review, we have collected detailed information on biochemical as well as pharmacological properties. The data were retrieved using different databases, such as Elsevier, PubMed, Science Direct, Google Scholar, and Scopus, and an extensive literature survey was carried out. Studies have shown that Acacia possesses several secondary metabolites, including amines, cyanogenic glycosides, flavonoids, alkaloids, seed oils, cyclitols, fluoroacetate, gums, non-protein amino acids, diterpenes, fatty acids, terpenes, hydrolyzable tannins, and condensed tannins. These compounds exhibit a wide range of pharmaceutical applications such as anti-inflammatory, antioxidant, antidiarrheal, antidiabetic, anticancer, antiviral, liver protective effects, and so on. Thus, the literature shows the tremendous phytochemical impact of the genus Acacia in medicine. Overall, we recommend that more research should be conducted on the medicinal value and isolation and purification of the effective therapeutic agents from Acacia species for the treatment of various ailments.