Seed pre-treatment is imperative for breaking the seed dormancy of some perennial species. The addition of soil amendments might be helpful in supporting seed germination and growth by available essential plant nutrients. This research investigated the effects of different pre-treatment and soil amendments on the germination, growth, and physiological performance of radhachura (Caesalpinia pulcherrima L.), an important ornamental and multipurpose woody shrub. Four pre-treatments and five soil amendments were applied in a CRD (Completely Randomized Design) arrangement to evaluate their individual and combined impacts under controlled nursery conditions. The ANOVA result revealed that seed germination indices of radhachura were mostly influenced by soil amendment rather than the seed pre-treatment. Among the soil amendments, vermicompost had a more profound impact on germination speed, Timson’s index and peak value, which had a similar effect to NPK application. Soil organic amendments positively affected growth, with vermicompost exerting the greatest influence on multiple germination traits that may support the early growth of radhachura, while biochar and compost maximized certain root and plant-length traits. Pearson correlations and PCA (first seven PCs explaining 76.2% variation) revealed the strong integration of late biomass, plant length, and root development, identifying vermicompost as key enhancers of multivariate vigor in radhachura seedlings. It might be concluded that C. pulcherrima L. species germination and growth was mostly influenced by soil amendment rather than seed pre-treatment. The study highlights that integrated nursery practices combining appropriate pre-treatment and soil amendments can enhance the germination success of radhachura.