Dr. Barbara-ann Guinn is a researcher at the Centre for Biomedicine, Hull York Medical School, University of Hull. She holds a B.Sc. in Genetics from the University of Aberyswyth (1991) and a Ph.D. from the University of Wales College of Medicine, Cardiff (1995). After completing her Ph.D., she worked as a postdoctoral fellow at the University of Toronto and later started her own research group at King's College London in 1999. Dr. Guinn is interested in identifying antigens that can be targeted for immunotherapy. Her research team has discovered that disease-specific proteins can provide valuable insights into disease biology and serve as biomarkers for disease stage and survival. Currently, her team is focusing on finding antigenic targets for the targeted therapy of adult B-cell acute lymphocytic leukemia, colon and ovarian cancer, as well as endometriosis and incidental lung nodules. Dr. Guinn's team has demonstrated that antigens can act as biomarkers for diagnosing disease, determining the subtype of the disease, and predicting survival rates. Their research has provided new insights into the underlying biology of these difficult-to-treat diseases.