Catalin Dumitru Cosma

Dr. Catalin Dumitru Cosma

Surgery I, "George Emil Palade" University of Medicine, Pharmacy, Science, and Technology of Târgu Mureș, Târgu-Mureş, Mureş, Romania
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Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2021 in Chirurgia
Verified
Journal Article
Closed access
CNCosmin Nicolescu
Cosmin Nicolescu
VBVlad Olimpiu Butiurca
Vlad Olimpiu Butiurca
Catalin Dumitru CosmaCatalin Dumitru Cosma
Catalin Dumitru Cosma
MBMihai Balan
Mihai Balan
ICIoana Iulia Cojocaru
Ioana Iulia Cojocaru
CMCalin Molnar
Calin Molnar
Background: In the case of patients admitted with acute abdomen at the emergency department, interstitial pulmonary pathology (Covid-19 infections) represents a significant operative risk for the patients. The rate of postoperative complications is high with increased morbidity and mortality, a real challenge for the medical staff and surgical/intensive care unit teams. In emergency settings, patients were examined with targeted clinical and paraclinical parameters that assure a fast diagnosis to optimize a rapid medical and surgical treatment. Methods: We conducted a retrospective comparative study that included patients enrolled and diagnosed with an acute surgical abdomen in Surgical Clinic 1 - Tg. Mures Emergency County Hospital. Patients were examined and analyzed at the emergency department UPU-SMURD. We included patients admitted over the two years (2019 and 2020) and divided them into two groups. Results: The total number of patients admitted in the UPU-Smurd emergency department - Surgical Clinic I over the two years was 1033. There was a significant reduction in total cases diagnosed with the acute surgical abdomen in the pandemic period (p=0.033). The average time from the admission to the surgical procedure was significantly higher in the pandemic period 380 +/- 2 min in comparison with 222 +/- 3 min (p=0.001) and also with an increased average operative time 223 +/- 3 min versus 145 +/- 2 min (p=0.002). Average hospitalization time was higher in the pandemic period 10 +/- 1 (p=0.031) with no significant difference between the groups regarding Intensive Care Unit (ICU) admission (p=0.122). Overall mortality has more than doubled, with 31 cases (19%) in the pandemic and 28 (9%) in the non-pandemic. (p=0.001). Conclusions: The COVID-19 pandemic has played an essential role in treating acute surgical abdomen cases. The high solicitation rate of the emergency department delayed the diagnosis and treatment of severe surgical cases. As the scale of this pandemic is unprecedented, standard protocols with minor changes do not provide adequate results

27 October 2025 in Medicina
Verified
Journal Article
Open access
PDF file
Catalin Dumitru CosmaCatalin Dumitru Cosma
Catalin Dumitru Cosma
Vlad-Olimpiu ButiurcaVlad-Olimpiu Butiurca
Vlad-Olimpiu Butiurca
MBMarian Botoncea
Marian Botoncea
Cosmin NicolescuCosmin Nicolescu
Cosmin Nicolescu
CRCristian Russu
Cristian Russu
CMCalin Molnar
Calin Molnar
Background and Objectives: The best method for reconstructing the stomach after distal gastrectomy surgery in gastric cancer patients continues to be a subject of ongoing discussion. The most beneficial surgical option for patients is Billroth I (BI), yet surgeons may perform Billroth II and Roux-en-Y (BII/RY) procedures because they are easier to execute, although their impact on recovery complications and postoperative function remains unclear. This prospective observational cohort study compares the short- and mid-term surgical outcomes between BI and BII/RY reconstructions. Materials and Methods: We included 150 patients who received curative intent distal gastrectomy at the General Surgical Clinic of Emergency County Hospital in Târgu Mureș, Romania, between October 2021 and December 2024 (72 BI and 78 BII/RY patients), with a mean age of 61.5 ± 10.8 years (60.7% male). The outcomes included recovery parameters, postoperative complications (Clavien–Dindo), and mid-term functional results (PPI use, Los Angeles classification esophagitis, bile reflux gastritis, Sigstad dumping score). Inverse probability of treatment weighting (IPTW) was applied to adjust for baseline covariates. Results: The results indicated that IPTW adjustment did not change the baseline demographics, tumor characteristics, or perioperative factors. The baseline characteristics were comparable between groups (p > 0.05). There were no significant differences in time to flatus (p = 0.12), oral diet (p = 0.70), or hospital stay (p = 0.69). Major morbidity (Clavien–Dindo ≥ III) occurred in 12.7% overall (p = 0.17), and the 90-day mortality was 5.3% (p = 1.00). At 6 months, bile reflux gastritis was more frequent after BII/RY (p = 0.16), whereas dumping syndrome occurred more often after BI (p = 0.16). Conclusions: The short-term surgical results, together with the total postoperative complications, showed no difference between the BI and BII/RY reconstruction methods. The study revealed distinct functional results between the two groups during the mid-term assessment, which demonstrates that surgeons should maintain their practice of choosing reconstruction techniques according to patient-specific requirements.

14 August 2025 in Cureus
Verified
Journal Article
Open access
PDF file
Catalin Dumitru CosmaCatalin Dumitru Cosma
Catalin Dumitru Cosma
TNTudor Negruti
Tudor Negruti
IEIoana Cosma Epure
Ioana Cosma Epure
CMCalin Molnar
Calin Molnar
DMDragos Molnar
Dragos Molnar
Acute airway obstruction secondary to a massive multinodular goiter represents a rare but critical surgical emergency, often occurring in patients with long-neglected thyroid disease. We report on an 85-year-old female who presented at Emergency County Hospital Tg Mures in March 2025 in critical respiratory distress, with documented tracheal deviation, orthopnea, and multiple episodes of cardiorespiratory arrest. Clinical and radiologic assessment revealed a giant anterior cervical mass with retrosternal extension and near-complete tracheal compression. Emergency airway control was achieved via awake fiberoptic intubation, followed by urgent total thyroidectomy. Intraoperative findings included significant tracheomalacia, prompting the need for concurrent tracheostomy. Postoperatively, the patient required intensive care monitoring and developed two systemic complications, a right hemispheric ischemic stroke and acute limb ischemia, both of which were managed conservatively. Histopathological analysis confirmed a benign multinodular goiter. This case emphasizes the importance of prompt recognition and surgical intervention in life-threatening compressive goiter, particularly in elderly patients, to prevent airway collapse and optimize outcomes.

7 November 2025 in Preprints.org
Verified
Preprint
Open access
PDF file
ACAdrian Cotovanu
Adrian Cotovanu
Catalin Dumitru CosmaCatalin Dumitru Cosma
Catalin Dumitru Cosma
CMCalin Molnar
Calin Molnar
Vlad-Olimpiu ButiurcaVlad-Olimpiu Butiurca
Vlad-Olimpiu Butiurca
MBMarian Botoncea
Marian Botoncea
Background and Clinical Significance: Synchronous gastrointestinal tumors are ex-ceptionally rare, particularly when combining histologically distinct benign and ma-lignant components. Schwannomas represent uncommon mesenchymal tumors of the gastrointestinal tract, most frequently arising in the stomach, while rectal localization is exceedingly unusual. Papillary adenocarcinoma of the gallbladder is an aggressive malignant entity derived from intracholecystic papillary-tubular neoplasms (ICPNs). The coexistence of these two unrelated neoplasms has not been previously reported, making this case of dual tumor pathogenesis clinically and academically significant. Case Presentation: A 68-year-old female was admitted for surgical management of grade IV uterovaginal prolapse. Preoperative imaging incidentally revealed a well-circumscribed rectal wall mass and gallstones. A combined abdominopelvic op-eration was performed, including total hysterectomy with bilateral adnexectomy (Wiart procedure), rectosigmoid resection with colorectal anastomosis, and bipolar cholecystectomy. Intraoperatively, a firm intramural rectal lesion and a friable papil-lary mass in the gallbladder fundus were identified. Histopathologic examination con-firmed a benign rectal schwannoma (S-100 positive, CD117/DOG-1 negative) and a papillary adenocarcinoma of the gallbladder, pT3N0M0, with clear resection margins and no lymphovascular or perineural invasion. The postoperative course was une-ventful, and the patient remained disease-free at six-month follow-up. Conclusions: This case represents an exceedingly rare benign–malignant synchronous tumor association. The simultaneous occurrence of rectal schwannoma and gallblad-der papillary adenocarcinoma underscores the importance of thorough intraoperative exploration and histopathologic evaluation. Complete resection with negative margins and multidisciplinary follow-up remains crucial for optimal outcomes and contributes to understanding dual tumor pathogenesis within the gastrointestinal tract.

31 December 2025 in Reports
Verified
Journal Article
Open access
PDF file
ACAdrian Cotovanu
Adrian Cotovanu
Catalin Dumitru CosmaCatalin Dumitru Cosma
Catalin Dumitru Cosma
CMCalin Molnar
Calin Molnar
Simona GurzuSimona Gurzu
Simona Gurzu
MBMarius-Alexandru Beleaua
Marius-Alexandru Beleaua
MBMarian Botoncea
Marian Botoncea
Background and Clinical Significance: Synchronous gastrointestinal tumors are exceptionally rare, particularly when combining histologically distinct benign and malignant components. Schwannomas represent uncommon mesenchymal tumors of the gastrointestinal tract, most frequently arising in the stomach, while rectal localization is exceedingly unusual. Papillary adenocarcinoma of the gallbladder is an aggressive malignant entity derived from intracholecystic papillary–tubular neoplasms (ICPNs). The coexistence of these two unrelated neoplasms has not been previously reported, making this case of dual tumor pathogenesis clinically and academically significant. C ase Presentation: A 68-year-old female was admitted for surgical management of grade IV uterovaginal prolapse. Preoperative imaging incidentally revealed a well-circumscribed rectal wall mass and gallstones. A combined abdominopelvic operation was performed, including total hysterectomy with bilateral adnexectomy (Wiart procedure), rectosigmoid resection with colorectal anastomosis, and bipolar cholecystectomy. Intraoperatively, a firm intramural rectal lesion and a friable papillary mass in the gallbladder fundus were identified. Histopathologic examination confirmed a benign rectal schwannoma (S-100 positive, CD117/DOG-1 negative) and a papillary adenocarcinoma of the gallbladder, pT3N0M0, with clear resection margins and no lymphovascular or perineural invasion. The postoperative course was uneventful, and the patient remained disease-free at six-month follow-up. Conclusions: This case represents an exceedingly rare benign–malignant synchronous tumor association. The simultaneous occurrence of rectal schwannoma and gallbladder papillary adenocarcinoma underscores the importance of thorough intraoperative exploration and histopathologic evaluation. Complete resection with negative margins and multidisciplinary follow-up remains crucial for optimal outcomes and contributes to understanding dual tumor pathogenesis within the gastrointestinal tract.

26 July 2023
Verified
Book Chapter
Open access
PDF file
NCNicolescu Cosmin
Nicolescu Cosmin
BSBogdan Andrei Suciu
Bogdan Andrei Suciu
ATAdrian Tudor
Adrian Tudor
CRCristian Russu
Cristian Russu
MGMircea Gherghinescu
Mircea Gherghinescu
CMCălin Molnar
Călin Molnar
This chapter deals with the emergency treatment of transverse colon cancer. The main complications that classify transverse colon cancer in an emergency setting are obstruction, perforation accompanied by localized or generalized peritonitis, and hemorrhage which may be occult or cataclysmic with hemorrhagic shock. We present the technical principles of radical surgical resection using embryological, anatomical, and oncological concepts. In this chapter we also discuss the principles of lymphadenectomy associated with complete excision of the mesocolon with high vascular ligation, in particular with T3 or T4 cancers requiring D2/D3 lymphadenectomy. The use of infrapyloric, gastro-epiploic, and prepancreatic lymphadenectomy is recommended due to the frequent metastases in these regional lymph nodes.