As part of her doctoral research, a series of experimental studies were conducted focusing on apoptosis, utilizing cellular and viral models. Research was also directed towards the regulation of NK cells, particularly their cytokine-mediated proliferation and survival. The activation mechanisms of NK cells were investigated, along with regulatory aspects of activation-induced cell death (AICD) within these cells. Further research at the University of Trieste centered on the effects of TNF-related apoptosis-inducing ligand (TRAIL) in lymphocyte and viral cellular models. The mechanism of apoptosis was analyzed during hematopoietic differentiation, along with an investigation into the role of nitric oxide (NO) in osteoclast differentiation. Research continues to explore the topical effects of plant extracts and graphene-based nanomaterials, as well as the toxic effects of palytoxins."