Daniel Genaro Rosas-Ramirez

Dr. Daniel Genaro Rosas-Ramirez

Departamento de Química de Biomacromoléculas, Instituto de Química, UNAM, Mexico City, Ciudad de México, Mexico
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Biography

My research focuses on the discovery, isolation, and characterization of bioactive metabolites from medicinal plants, particularly glycolipids from the Convolvulaceae family, with potential applications in the treatment of diabetes and other diseases. I specialize in the extraction, isolation, and purification of natural products using various chromatographic techniques, followed by comprehensive structural elucidation using advanced spectroscopic methods, such as NMR, mass spectrometry, and other physicochemical and theoretical analyses for accurate metabolite identification. A central aspect of my research is the evaluation of enzyme-ligand interactions using affinity-based assays to investigate how these metabolites modulate key metabolic enzymes involved in glucose homeostasis. This approach enables the rapid isolation and identification of bioactive compounds from complex matrices, such as plant extracts. These experimental studies are complemented by molecular modeling to predict and optimize compound–target interactions, thereby facilitating the discovery and development of promising drug candidates.

Affiliations

Instituto de Química, UNAM

Mexico City, Ciudad de México, Mexico

Departamento de Química de Biomacromoléculas

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Experience

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