There is increasing recognition that pharmacotherapy alone cannot prevent recurrences of bipolar disorder or fully alleviate postepisode symptoms or functional impairment.
1 Psychotherapy, when provided at all, is viewed as an adjunctive treatment.
2 Evidence from randomized clinical trials (RCTs) indicates that combining pharmacotherapy with manualized psychotherapies—including cognitive behavioral therapy (CBT), family-focused therapy, interpersonal and social rhythm therapy (IPSRT), and group psychoeducation—is more effective than pharmacotherapy alone in stabilizing symptoms and reducing recurrences among outpatients with bipolar disorder.
1,3,4 The comparative effectiveness of these approaches, however, has received scant attention.