David Spain

Prof. David Spain


Research Focus & Metrics

Academic Career Length

33Years (1994-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 August 2017 in World Journal of Emergency Surgery
Verified
Journal Article
Open access
PDF file
ACand Federico Coccolini
and Federico Coccolini
GMGiulia Montori
Giulia Montori
Fausto CatenaFausto Catena
Fausto Catena
YKYoram Kluger
Yoram Kluger
WBWalter Biffl
Walter Biffl
LALuca Ansaloni
Luca Ansaloni
Spleen injuries are among the most frequent trauma-related injuries. At present, they are classified according to the anatomy of the injury. The optimal treatment strategy, however, should keep into consideration the hemodynamic status, the anatomic derangement, and the associated injuries. The management of splenic trauma patients aims to restore the homeostasis and the normal physiopathology especially considering the modern tools for bleeding management. Thus, the management of splenic trauma should be ultimately multidisciplinary and based on the physiology of the patient, the anatomy of the injury, and the associated lesions. Lastly, as the management of adults and children must be different, children should always be treated in dedicated pediatric trauma centers. In fact, the vast majority of pediatric patients with blunt splenic trauma can be managed non-operatively. This paper presents the World Society of Emergency Surgery (WSES) classification of splenic trauma and the management guidelines.

1 October 2013 in Annals of Emergency Medicine
Verified
Journal Article
Closed access
MDM. Kit Delgado
M. Kit Delgado
KSKristan L. Staudenmayer
Kristan L. Staudenmayer
NWN. Ewen Wang
N. Ewen Wang
DSDavid Spain
David Spain
SWSharada Weir
Sharada Weir
JGJeremy D. Goldhaber-Fiebert
Jeremy D. Goldhaber-Fiebert

1 January 2021 in Current Problems in Surgery
Verified
Journal Article
Closed access
JCJeff Choi
Jeff Choi
GCGarrison Carlos
Garrison Carlos
ANAussama K. Nassar
Aussama K. Nassar
LKLisa M. Knowlton
Lisa M. Knowlton
DSDavid Spain
David Spain

1 May 2014 in JAMA Surgery
Verified
Journal Article
Open access
PDF file
MDM. Kit Delgado
M. Kit Delgado
MYMichael A. Yokell
Michael A. Yokell
KSKristan L. Staudenmayer
Kristan L. Staudenmayer
DSDavid Spain
David Spain
THTina Hernandez-Boussard
Tina Hernandez-Boussard
NWN. Ewen Wang
N. Ewen Wang
Trauma is the most common cause of years of life lost for those younger than 65 years, and it exacts $406 billion per year in costs, more than heart disease or cancer.1,2 Acute care in specialized trauma centers has been shown to reduce mortality by 25% in patients with major trauma.3 While direct transport from the scene of injury to a designated trauma center is optimal, patients who are taken to non–trauma center emergency departments (EDs) and who are then transferred in a timely fashion to trauma centers have reduced mortality compared with those who are hospitalized at the non–trauma center.4,5 Regionalized trauma systems have been developed during the past 3 decades to optimize population-level outcomes by facilitating the direct transport or transfer of patients with severe injuries to designated trauma centers.6,7

1 August 2005 in The American Journal of Surgery
Verified
Journal Article
Closed access
DSDavid Spain
David Spain
FMFrank B. Miller
Frank B. Miller

1 February 2006 in Archives of Surgery
Verified
Journal Article
Closed access
PDF file
DLDarren R. Lebl
Darren R. Lebl
RDRochelle A. Dicker
Rochelle A. Dicker
DSDavid Spain
David Spain
SBSusan I. Brundage
Susan I. Brundage
Hypothesis Traumatic thoracic aortic injury (TAI) is traditionally treated with immediate surgery. Previously published studies have established the safety and efficacy of treating TAI with endovascular stents. Our hypothesis was that stents are supplanting operative repair as the primary therapy for TAI. Design Retrospective cohort. Setting University level I trauma center. Patients and Methods Blunt trauma patients admitted to a level I trauma center diagnosed with TAI between September 1997 and November 2003 were identified from an institutional trauma registry (N = 25). Data were abstracted from medical records and analyzed. Three groups were defined: surgical repair (cardiopulmonary bypass or clamp and sew) (n = 10); medical management (n = 8); and endovascular stent (n = 7). Results Prior to 2002, 9 (75%) of 12 patients were treated by surgical repair, 2 (17%) by medical management, and 1 (8%) by endovascular stent. Since 2002, 1 patient (8%) was treated by surgical repair, 6 (46%) by medical management, and 6 (46%) by endovascular stent. Injury Severity Scores were comparable between the surgical cohort (mean ± SEM score, 34.9 ± 3.4), stent placement (35.1 ± 3.7), and medical management (29.9 ± 2.8) (P = .48). Overall survival was 80% with no differences in morbidity or mortality. The stented group had shorter hospital lengths of stay compared with surgical management (28 vs 46 days) (P<.05). The 1 operative case since 2002 was a combined arch/innominate injury that anatomically precluded stent placement. Conclusion Initial reports suggested thoracic aortic stents as an alternative for injured patients with prohibitive operative risks. Our data suggest stent placement is quickly evolving into the primary therapy for TAI across all Injury Severity Score profiles.