Laura Dayanara López Rocha

Prof. Laura Dayanara López Rocha

Universidad Autonoma de Baja California- Facultad de Medicina Mexicali
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orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 March 2022 in Applied Sciences
Verified
Journal Article
Open access
PDF file
JGJavier González-Ramírez
Javier González-Ramírez
GMGustavo Martinez-Coronilla
Gustavo Martinez-Coronilla
Laura Dayanara López RochaLaura Dayanara López Rocha
Laura Dayanara López Rocha
AMAna Gabriela Leija Montoya
Ana Gabriela Leija Montoya
Adrián Hernández-DíazcouderAdrián Hernández-Díazcouder
Adrián Hernández-Díazcouder
Fausto Sanchez-MunozFausto Sanchez-Munoz
Fausto Sanchez-Munoz
By 2030, non-communicable diseases will have accounted for more than three-quarters of deaths worldwide. Cardiovascular diseases (CVDs) have been the leading cause of death worldwide for several years. Acute myocardial infarction (AMI) is a CVD characterized by necrosis of the heart at the myocardial level due to prolonged ischemia caused by the reduction or sudden absence of coronary blood supply. The prevalence of AMI is higher in men at all ages. The incidence of AMI has decreased in industrialized nations; however, it has been on the rise in Latin America (LATAM) due to lifestyle changes. These changes have caused the combined incidence of CVDs and unresolved health concerns in LATAM, such as infections and malnutrition. It is well known that periodontitis, a highly prevalent chronic infectious inflammatory disease, has been associated with systemic diseases, such as diabetes, kidney diseases, and AMI. This review addresses proposed aspects of the correlation between periodontitis and AMI, explains the importance of preventing periodontitis and CVDs, and analyzes the preventative measures being implemented in LATAM, particularly in Mexico.

Verified
Journal Article
Open access
PDF file
Laura Dayanara López RochaLaura Dayanara López Rocha
Laura Dayanara López Rocha
ARArmando Ruiz-Hernández
Armando Ruiz-Hernández
GMGustavo Martinez-Coronilla
Gustavo Martinez-Coronilla
AMAna Gabriela Leija Montoya
Ana Gabriela Leija Montoya
MPMario Peña Peña
Mario Peña Peña
JGJavier González-Ramírez
Javier González-Ramírez
Anxiety is a fear response that triggers a stress reaction with the purpose of defending against or avoiding danger, which is considered physiological, until it becomes excessive and persistent, affecting daily life activities. Non-coding RNAs have been explored in terms of their relationship with diseases, and several of them, such as miRNAs, have been found to be key factors in the development of diseases. Specifically, the expression of long non-coding RNAs (lncRNAs) has been implicated in the development of anxiety through various mechanisms such as nervous system development, synaptic function, neurotransmitter regulation, and neuroinflammation. However, several recent reviews have explored the roles of lncRNAs in various mental diseases (mainly in schizophrenia), and considering that existing reviews do not cover the interaction between lncRNAs and aspects such as neuroimmunity in anxiety disorder pathophysiology, the aim of this literature review is to summarize the current knowledge about the contributions of lncRNAs to the molecular and cellular mechanisms underlying the pathogenesis of anxiety disorders. Additionally, we explore their potential applications in the diagnosis, as well as possible treatment approaches, of these disorders, challenges, and current limitations.