The primary research interest of our laboratory is Translational Cancer Research and to investigate altered metabolic states in several cancers, including Head and Neck, Breast, Prostate and Pancreatic cancer. Our lab is focused on understanding the molecular mechanism (s) of the regulation of Autophagy and Apoptosis in Cancer Stem Cells (Prostate, Pancreatic and Breast). Specifically, to understand the molecular mechanism (s) of induced Autophagy in Cancer Stem Cells (CSCs) via PI3K/Akt/mTOR signaling pathways. Our lab is also working on molecular cross-talk between tumor microenvironment (Cancer Associated Fibroblast (CAF)) and cancer/cancer stem cells, mutational heterogeneity in solid tumor, exosome secretion from cancer and cancer stem cells and it's role in tumor progression, gene editing using CRISPR-Cas9 technology, NGS and Bioinformatics.