The COVID-19 pandemic placed critical care nurses at the forefront of patient care, exposing them to high levels of occupational stress, which can negative

Background and Objective: Medicinal plants have been known to play a crucial role in the health system since time immemorial as plants contain natural compounds with medicinal properties. This research is aimed at profiling and investigating the hypolipidemic effect of ethanol extract of Mangifera indica in streptozotocin-induced diabetic Wistar rats. Materials and Methods: The albino Wistar rats weighing 110 to 242 g were randomly distributed into six groups of five rats each. Group I served as a normal control and was given feed and distilled water. Group II served as diabetic control. Groups III, IV, V and VI were induced with 40 mg/kgb. of streptozotocin. Group III was treated with 5 units/b.wt., of insulin. Group IV, V and VI were treated with 200, 300 and 400 mg/kg of Mangifera indica extract respectively. The duration of treatment was twenty one days. Extraction and biochemical analysis were carried out using standard laboratory techniques. The chemical components of the leaf extracts were characterized by GCMS analysis. Results: Administration of the extract resulted in a significant (p<0.05) decrease in TG, TC and LDL concentrations in all experimental groups when compared to the control group but an increase in HDL and VLDL concentrations. Conclusion: It may be concluded that the ethanol leaf extract of Mangifera indica may possess hypolipidemic properties and could be used to regulate lipid levels. The plant extract's GC-MS examination revealed that the most prevalent compounds were oleic acid, 9,12-octadecadienoic acid and 9,12-octadecadienal, etc. APA-7 Style Amaechi, D., Ekpe, I.P., Yisa, B.N., Adamgbe, T.F. (2024). Phytochemical Profiling (GC-MS) of the Leaf Extract of Mangifera indica and its Hypolipidemic Effect on Serum Lipid Profile in Streptozotocin-Induced Diabetic Wistar Rats. Asian Science Bulletin, 2(1), 17-23. https://doi.org/10.3923/asb.2024.17.23 ACS Style Amaechi, D.; Ekpe, I.P.; Yisa, B.N.; Adamgbe, T.F. Phytochemical Profiling (GC-MS) of the Leaf Extract of Mangifera indica and its Hypolipidemic Effect on Serum Lipid Profile in Streptozotocin-Induced Diabetic Wistar Rats. Asian Sci. Bul 2024, 2, 17-23. https://doi.org/10.3923/asb.2024.17.23 AMA Style Amaechi D, Ekpe IP, Yisa BN, Adamgbe TF. Phytochemical Profiling (GC-MS) of the Leaf Extract of Mangifera indica and its Hypolipidemic Effect on Serum Lipid Profile in Streptozotocin-Induced Diabetic Wistar Rats. Asian Science Bulletin. 2024; 2(1): 17-23. https://doi.org/10.3923/asb.2024.17.23 Chicago/Turabian Style Amaechi, Dennis, Ini Patrick Ekpe, Benjamin Nma Yisa, and Theresa Faeren Adamgbe. 2024. "Phytochemical Profiling (GC-MS) of the Leaf Extract of Mangifera indica and its Hypolipidemic Effect on Serum Lipid Profile in Streptozotocin-Induced Diabetic Wistar Rats" Asian Science Bulletin 2, no. 1: 17-23. https://doi.org/10.3923/asb.2024.17.23

Objectives: The objectives of this research is to evaluate the effects of aqueous extract of T. indica on weight, lipid parameters, some electrolytes and urea of Wistar rats Design & Methods: Twenty-five Male Adult rats were grouped into four consisting of six rats each. Group I served as control group, group II was administered 100mg/kg of the Aqueous extract, group III was administered 150mg/kg of the Aqueous extract, and Group IV was administered 200mg/kg of the Aqueous extract. The administration took place for seven days, and on the eight day, The Animals were sacrificed. The blood samples was collected via cardiac puncture and used for analysis using a visible spectrophotometer. Results: From the result, there was no significant difference (p<0.05) in body weight of Wistar rats. In the Test Groups; Serum cholesterol, low density lipoprotein (LDL), High density lipoprotein (HDL), Very Low-density Lipoprotein and Triglycerides revealed a significant increase (p<0.05) compared to Group 1 which is the control Group but had a significant decrease (p<0.05) compared within test groups. For electrolytes concentrations, potassium, Sodium, Chloride and Urea concentrations was significant at p<0.05. Conclusion: the results above ,T. indica extract may help to maintain healthy weight, may have hypolipidemic properties, may help in body homeostatic and fluid balance and may also prevent renal damages.

Sexual health is a fundamental component of quality of life that is frequently compromised in cancer patients. In melanoma care, these issues remain under addressed despite increasing survivorship. This scoping review aimed to map the current literature on sexual health concerns in melanoma patients. Following PRISMA-ScR guidelines, five databases were searched (2010-2025). Ten studies met the inclusion criteria, including cross-sectional, qualitative, and systematic reviews. Sexual dysfunction affected up to 52% of melanoma patients, with higher prevalence in men (68.9%) than women (41.3%). Contributing factors included visible scarring, hormonal imbalances (e.g., testosterone deficiency in 69% of men receiving immunotherapy), body image concerns, anxiety, and depression. Women were more affected by body image and recurrence anxiety, while men experienced higher rates of treatment-induced hypogonadism. In one cross-sectional study (n = 75), sexual dysfunction was reported in up to 52% of melanoma patients, with higher rates in men (68.9%) than women (41.3%); however, these estimates are based on limited data and should not be generalized.

Background of the Study: Lead effects were assessed by analyzing the impacts of the extract on the liver enzyme concentrations and hematology parameters. Materials and Methods: Thirty five male wistar rats weighing 85-110 g were distributed into five groups consisting of seven rats each. Group I served as control group, group II served as the test group, groups III, IV and V served as treatment groups. Lead acetate solution was given to the rats orally at a dose of 50 mg/kg body weight and 200 mg/kg of fruit extracts for 14 days. On day 15, biochemical analysis were carried out. Results: Effects of extracts showed that ALT,AST and ALP concentration in group II was observed to be significantly (p<0.05) higher than the control and treatment groups with values. The hematology results showed that lead did not cause a significant reduction in the packed cell volume, white blood cell and red blood cell counts. However, the group treated with carrot and garden egg showed slight increase in RBC and WBC count when compared with the positive and negative control groups. Conclusion: From the results above, it showed that the fruits extract have hematopoietic potentials and hence aid in the hepatoprotection of the liver of lead induced Wistar rats.

Background and Objective: Plants are a significant source of medicinal compounds that play a crucial role in global health and serve as an important potential source of treatments. Medicinal plants which are widely used across various health systems, serve not only to treat illnesses but also to maintain overall health. This research is aimed at investigating the hypolidaemic effects of ethanol leaf extract of Eucalyptus camaldulensis in Wistar rats. Materials and Methods: The study involved 40 rats divided into six groups, each given different doses of a plant extract. Biochemical analysis was performed using standard laboratory techniques and significant changes were considered acceptable at a p<0.05 level. Results: Administration of the extract resulted in no significant changes in TC, TG, LDL and VLDL concentrations in all experimental groups when compared to the control group. However, there was a significant increase (p<0.05) in HDL at 150 mg/kg (365.00±46.10) and 450 mg/kg (390.00±75.06). Conclusion: The ethanol leaf extract of Eucalyptus camaldulensis, particularly at doses of 150 and 450 mg/kg, significantly increased HDL levels in the Wistar rats. This suggests its potential as a rapeutichypolidaemic agent which may be responsible for reducing cardiovascular disease risk. APA-7 Style Amaechi, D., Mary, A.E., Ekpe, I.P., Benjamin, Y.N., Kaura, S., Fredrick, C.C., Chidinma, N.L. (2024). Hypolipidaemic Effects of Ethanol Leaf Extract of Eucalyptus camadulensis in Wistar Rats. Asian Journal of Biological Sciences, 17(4), 846-851. https://doi.org/10.3923/ajbs.2024.846.851 ACS Style Amaechi, D.; Mary, A.E.; Ekpe, I.P.; Benjamin, Y.N.; Kaura, S.; Fredrick, C.C.; Chidinma, N.L. Hypolipidaemic Effects of Ethanol Leaf Extract of Eucalyptus camadulensis in Wistar Rats. Asian J. Biol. Sci 2024, 17, 846-851. https://doi.org/10.3923/ajbs.2024.846.851 AMA Style Amaechi D, Mary AE, Ekpe IP, Benjamin YN, Kaura S, Fredrick CC, Chidinma NL. Hypolipidaemic Effects of Ethanol Leaf Extract of Eucalyptus camadulensis in Wistar Rats. Asian Journal of Biological Sciences. 2024; 17(4): 846-851. https://doi.org/10.3923/ajbs.2024.846.851 Chicago/Turabian Style Amaechi, Dennis, Ameh Enyojo Mary, Ini Patrick Ekpe, Yisa Nma Benjamin, Sunday Kaura, Christy Chinyere Fredrick, and Nnolim Lucia Chidinma. 2024. "Hypolipidaemic Effects of Ethanol Leaf Extract of Eucalyptus camadulensis in Wistar Rats" Asian Journal of Biological Sciences 17, no. 4: 846-851. https://doi.org/10.3923/ajbs.2024.846.851