Prof. Edward L. D'Antonio is a Professor of Biochemistry and Structural Biology at the University of South Carolina Beaufort (USCB). He received his Ph.D. in Chemistry at North Carolina State University in 2010 under the direction of Prof. Edmond F. Bowden, where his research areas of focus were in Biochemistry, Bioinorganic Chemistry, and Redox Thermodynamics. From 2010 to 2013, he held a Postdoctoral Fellowship at the University of Pennsylvania under the direction of Prof. David W. Christianson, and he was trained in Structural Biology and Medicinal Chemistry. Dr. D’Antonio started his teaching role and independent scientific career in 2013. The main goal of his research program functions to identify chemical compounds that inhibit protein targets of pathogenic microorganisms or viruses. Over the past decade, Dr. D’Antonio has been studying the parasite Trypanosoma cruzi, which is the etiological agent for Chagas’ disease. The drug discovery strategies that he utilizes include structure-based drug design, hit-to-lead expansions, structure–activity relationships, the development of enzymatic assays, and high-throughput screening. Compounds are further developed by experimentally searching for higher efficacy and lower toxicity than the clinically used therapeutics for the treatment of neglected tropical diseases.
University of South Carolina Beaufort
Bluffton, South Carolina, USA
Outstanding Undergraduate Research Mentor Award (2018)
University of South Carolina
One of three awards selected throughout all campuses of the state for the University of South Carolina.
The American Institute of Chemists Foundation Award (2008)
The American Institute of Chemists Foundation
Full Professor of Biochemistry and Structural Biology
University of South Carolina Beaufort
01 Aug 2023 - present
Associate Professor of Biochemistry and Structural Biology
University of South Carolina Beaufort
01 Jul 2018 - 01 Aug 2023
Assistant Professor of Biochemistry and Structural Biology
University of South Carolina Beaufort
01 Jul 2013 - 01 Jul 2018