Atmospheric air pollution is a major environmental and public health concern, particularly in industrialized regions. The East Kazakhstan Region exhibits high rates of oncological, cardiovascular, and respiratory diseases. However, the specific impact of industrial emissions on morbidity remains insufficiently studied. This study employed correlation and regression analyses using data on pollutant emissions and population morbidity indicators from 2014 to 2023. Correlation and regression methods, along with geoinformation technologies, were applied. A moderate positive correlation was found between industrial emission volumes and the incidence of neoplasms (r = 0.59, R² = 0.35), especially in areas with high concentrations of sulfur dioxide, nitrogen oxides, and particulate matter. The findings confirm the significant influence of polluted air—particularly mixed pollutants—on the increase in cancer-related diseases. The conclusions emphasize the urgent need to implement emission reduction measures, enhance environmental monitoring and disease prevention, and carry out further epidemiological research.

Industrial settlements of the East Kazakhstan Region face a persistent technogenic burden driven by the dense concentration of non-ferrous metallurgy and heat-and-power enterprises, further compounded by unfavorable pollutant dispersion conditions inherent to the region’s mountain–basin topography. This study evaluated spatiotemporal associations between annual mean concentrations of NO₂, SO₂, H₂S, and CO, the integrated air pollution index (API₅), and primary neoplasm morbidity across five settlements over the period 2014–2024. A retrospective ecological analysis was carried out for Ust-Kamenogorsk, Ridder, Altai, Shemonaikha, and the settlement of Glubokoe, incorporating Spearman’s rank correlation, lag analysis (1–3 years), and the Mann–Kendall trend test. Throughout the study period, neoplasm morbidity in the region consistently exceeded the national average by a factor of 1.3 to 2.0. In Ust-Kamenogorsk—where metallurgical SO₂ and NO₂ emissions are most heavily concentrated—strong positive associations were found in children for SO₂ (ρ = 0.791, p < 0.05) and in adolescents for NO₂ and CO, reflecting elevated inhalation exposure under conditions of chronic pollution. The negative associations with API₅ observed in Ridder and Altai, where the index showed a statistically significant downward trend, are interpreted as evidence of the inertial character of oncological processes and the lasting influence of cumulative past exposure. Across all studied settlements, SO₂ emerged as the most consistent predictor of morbidity variation. These findings support prioritizing stricter emission controls for SO₂ and NO₂ from metallurgical and energy facilities, establishing oncological screening programs for children and adolescents in chronically polluted areas, and strengthening ambient air monitoring—measures whose effective implementation will require coordinated action between public health authorities and environmental regulators.

This work is dedicated to the study of impact of local vibration on the health of miners in the East Kazakhstan region, where mining industry is one of the leading sectors of the economy and a major source of employment. Vibration disease is one of the most common occupational diseases among workers who use vibration-prone equipment on a regular basis. Vibration, combined with other harmful factors such as industrial noise, poor microclimate, and heavy physical loads, negatively affects workers' health and significantly contributes to the development and progression of vibration pathology. The study used mathematical modeling methods to analyze the relationship between vibration dose, exposure time, and the body's physiological response. Special attention was given to eco-rehabilitation measures aimed at improving working conditions and reducing the risks of occupational diseases in hazardous environments. The work presents practical recommendations for organizing effective protective measures for workers, including compliance with sanitary and hygienic standards, reducing vibration exposure, conducting regular preventive medical examinations, and improving the occupational medical care system. The results of the study can be used to develop and implement new standards and recommendations for the mining industry to improve working conditions and protect the health and long-term well-being of miners.

Металлургияның бір саласы болып табылатын титан-магний өндірісінің бірқатар технологиялық кезеңдері айтарлықтай жылу шығарумен сипатталады. Көптеген зерттеулер микроклиматтың адам ағзасына жағымсыз әсерін көрсетеді. Жоғары ауа температурасы және қарқынды сәулелену термореттелудің, орталық жүйке жүйесінің және жүйке-бұлшықет аппаратының едәуір кернеуін тудырады. Қыздырушы микроклимат әсіресе қарқынды бұлшықет жұмысы мен жүйке-эмоциялық стресс кезінде өндірістік шудың ғана емес, сонымен қатар ауадағы зиянды газдар мен улы заттардың теріс әсерін күшейтеді. Титан-магний өндірісінде еңбек іс-әрекеттері жоғары температура, жылу, шаң және газ бөлу жағдайларында іске асырылады. Бір ауысымда жұмысшылар уақыттың 70% еңбек операцияларын іске асыруға жұмсайды. Электролизерлерге карналлиттің сусыз құймасы құйылады. Мұнда электролизшілер-реттегіштер, электролизшілер-вакуумшылар, анодшылар, хлорлаушылар жұмыс істейді, олар құйманы құю барысында 1,5-2,0 метр қашықтықта тұрғанымен, сәулелі жылудың, магний аэрозольдерінің, оның оксидтерінің, магний хлоридінің әсеріне ұшырайды. Операция айтарлықтай физикалық күш жігерді қажет етеді. Титан-магний өндірісінің негізгі цехтарындағы ауа ортасын гигиеналық зерттеу негізгі цехтардың жұмыс аймақтарының ауасында күкірт газы, сутегі хлориді, магний хлориді си-яқты улы химиялық заттардың бар екені белгілі болды. Аталмыш заттардың концентрациясы рұқсат етілген деңгейден ондаған есе көп. Әдебиет көздерінде магний мен титан өндірісінің зиянды компоненттерінің және олардың қосылыстарының ағзаға әсері туралы еңбектер санаулы. Титан мен магний өндірісіндегі еңбек жағдайлары жұмысшылардың денсаулығына теріс әсер етеді. Жетекші кәсіп жұмысшыларында тыныс алу мүшелерінде (созылмалы уытты бронхит, созылмалы шаңды бронхит, пневмокониоз, бронхиолит, уытты бронхопневмосклероз), сондай-ақ жүйке жүйесінде (астеновегативті синдром, дисциркуляторлық энцефалопатия), сүйек-бұлшықет жүйесінде (мойын және бел остеохондрозы, артроз және т.б.) кәсіби сипаттағы өзгерістер дамиды. Жұмысшыларда тұмау, жоғарғы тыныс жолдарының жедел катаралды ауруы, баспа, жедел және созылмалы сипаттағы асқазан мен ішек аурулары, невралгия, радикулит, артрит, фурункулдар, карбункулалар, экзема, дерматит, миозит сияқты спецификалық емес аурулар жиі кездеседі.

The industrial settlements of East Kazakhstan have long been exposed to ambient air-pollution pressure, yet the association between gaseous pollutants and cardiovascular morbidity in the region’s population remains insufficiently studied. This study aimed to assess the association between ambient air pollution and the primary incidence of circulatory system diseases in the population of the industrial settlements of East Kazakhstan (Ust-Kamenogorsk, Ridder, Glubokoe, and Altai) over the period 2014–2024. A retrospective ecological analysis of annual data on H₂S, SO₂, CO, NO₂, the API₅, and primary incidence of circulatory-system diseases (CSD) was conducted. Associations were assessed using Spearman correlation with FDR correction, lag analysis, and partial rank correlation controlling for the calendar year. After FDR correction, nine comparisons retained statistical significance, all in Ridder, corresponding to six exposure–outcome combinations (ρ = −0.718 to −0.828; q = 0.020–0.0498). After controlling for the calendar year, none of these comparisons remained statistically significant. The lag analysis at shifts of 1–3 years likewise revealed no associations that retained significance after FDR correction. The associations identified were sensitive to the overall temporal trend. The results do not confirm a robust independent or delayed association between the air pollution indicators studied and primary cardiovascular morbidity within the framework of the aggregated annual data; they do not, however, exclude an adverse effect that a larger study with higher temporal resolution might detect.

The leading place in research and forecasting of professional activity is occupied by the problem of diagnostics of psychophysiological properties of a person. The most typical state of workers engaged in hazardous production is emotional tension, which affects the efficiency of production activity. Highly toxic substances, which include beryllium used in beryllium production, can cause psychophysiological tension and can serve as a basis for acute and chronic emotional stress. The scientific article describes the influence of production factors on the psychophysiological status of workers of beryllium shop of JSC ‘UMP’ depending on age. The psychophysiological status of workers of the examined groups is distributed unevenly. The increase in the number of workers with values of high personal anxiety and low rate of motor activity is mutually conditioned by the work associated with a high degree of emotional tension. The highest level of reactive and personal anxiety in combination with a low rate of motor activity is observed in workers of the third group (aged 45-65 years), and is accompanied by an increase in stress values in the Lusher test and low values of mental efficiency. Inclusion of psychophysiological testing in the course of professional selection allows to reveal the peculiarities of protective and adaptive reactions in workers of different age groups. Keywords:: beryllium production workers, toxic effect, anxiety level, reactive anxiety, personality anxiety