JMPJ (Hans) Breur is an experienced interventional pediatric cardiologist. He is an associate professor of pediatric cardiology and has published over 100 papers in international peer reviewed journals. His research focusses on improving cardiac and neurocognitive outcome in patients with severe congenital heart disease. He is one of the founders of the Congenital Heart Disease life span program in 2016: a unique life cycle follow-up program fully integrated in clinical follow care from as early of 20 weeks gestation up to adulthood. Cardiac- as well as neurocognitive follow-up is protocolized for all major congenital heart defects and includes sequential MRI scanning of the heart and brain (fetal as well as pre- and postoperative). Follow-up is fully aligned with the other patient focus groups of the Child Health and Circulatory Health programs of the UMC Utrecht. This program has resulted in the initiation of the “Crucial trial” (“CeRebrUm and Cardlac protection with ALlopurinol in neonates with duct-dependent congenital heart disease requiring cardiac surgery with cardiopulmonary bypass) in 2020. This national trial is funded by ZonMW (€1.5M). Dr. Hans Breur is involved as PI or co-PI in several national and international research collaborations and was awarded over €5M in national (Stichting Hartekind, Hartstichting, vrienden UMCU) and international (EU) grants. Collaboration to improve patient outcome has been the basis for all of his grant applications. H