Heiner Schäfer: Cell Biologist by training (1982-1989 at University of Göttingen, Germany), Doctoral Degree (PhD) in 1993, Post-Doc at the Medical University Hospital Kiel (1993-1999), Associate Professor at the Kiel University (Medical Faculty, 1999-2003) and Professor since 2004. Head of the Laboratory of Molecular Gastroenterology at the Medical University Hospital Kiel (1998-2015) and at the Institute of Experimental Cancer Research (Kiel) since 2016. Work Experience in NF-kB- and Nrf2-signaling, metabolic reprogramming and tumor-stroma interactions in pancreatic and colorectal cancer. Major research activity on Signal Transduction and Resistance Mechanisms in GI-cancers with the current focus on Nrf2 dependent metabolic reprogramming. Memberships: American Association of Cancer Research (Associated Member), German Cell Biology Society. Awards: Hensel Prize (University of Kiel, 2001), Vincenz Czerny-Prize (German Society of Hematology & Oncology, 2001), Ludolph-Brauer-Prize (Northwestern Society of Internal Medicine, 1998), Basic Pancreatic Science Award (European Pancreatic Club, 1996), Research Prize of the Medical Society of Kiel (University of Kiel), Young Scientist Research Prize (United European Gastroenterology Week, 1995). ORCID-ID: 0000-0001-6936-9090