Purpose: To assess the role of inflammation in the pathogenesis of idiopathic epiretinal membrane (iERM) using the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and mean platelet volume (MPV) as indicators of inflammation and to compare these parameter levels between iERM and control subjects. Methods: We retrospectively analyzed the medical records of 36 patients who underwent vitrectomy-ERM peeling and 39 patients who had cataract surgery. We obtained blood samples from all individuals who participated in the study to investigate these parameters. Results: Seventy-five subjects were included in this study: 36 in the iERM group and 39 in the control group. The mean neutrophil and MPV levels were significantly higher in iERM subjects than in control subjects. The mean lymphocyte level was lower in the iERM group. The mean NLR, PLR, and MPV levels were higher in iERM subjects than in control subjects. Conclusion: The higher NLR, PLR, and MPV levels found in patients with iERM may indicate that subclinical systemic inflammation may associate with iERM.

Purpose: To compare the visual and refractive outcomes of keratorefractive lenticule extraction (KLEx) using the VISUMAX 800 femtosecond laser and femtosecond laser-assisted in situ keratomileusis (FS-LASIK) performed using the VISUMAX 800 femtosecond laser and the EX500 excimer laser in the treatment of myopic astigmatism. Setting: Single-center, private ophthalmology center. Design: Retrospective comparative study. Methods: 237 eyes (133 KLEx, 104 FS-LASIK) were evaluated. Cyclotorsion alignment in KLEx was achieved using the Callisto Eye system integrated with VISUMAX 800. Refractive outcomes, vector analysis (Alpins method), and safety and efficacy indices were compared between groups at 1 month and 6 months postoperatively. Results: At 6 months, both groups achieved comparable uncorrected distance visual acuity (0.01 ± 0.04 logMAR) and corrected distance visual acuity. Mean spherical equivalent was closer to emmetropia in the KLEx group (−0.04 ± 0.18 diopters [D] vs −0.10 ± 0.15 D, P = .007). Residual cylinder was lower in KLEx (−0.14 ± 0.19 D vs −0.20 ± 0.20 D, P = .010). Vector analysis showed lower difference vector in KLEx (0.14 ± 0.19 D vs 0.21 ± 0.21 D, P = .009), while FS-LASIK had a slightly higher correction index (correction index: 1.02 vs 0.97, P = .005). Conclusions: Both KLEx and FS-LASIK performed using the VISUMAX 800 achieved excellent refractive outcomes, with KLEx procedures incorporating an image-guided static cyclotorsion alignment strategy and demonstrating excellent refractive and vector analysis results.

The objectiove of the study is to evaluate and compare the outcomes of pars plana vitrectomy (PPV) and PPV combined with scleral buckle (SB) in vitrectomised cases with recurrent retinal detachment (RD) and to analyze the effects of adding SB to the procedure. Patients with recurrent RD due to grade C proliferative vitreoretinopathy (PVR) were included in this retrospective comparative case series. Patients who underwent re-PPV with or without SB were included and two groups (re-PPV; re-PPV+SB) were compared in terms of anatomical and functional success. Sixty-five cases were included in the study: 32 underwent re-PPV and 33 underwent re-PPV+SB procedures. Reattachment was achieved in 59.4% of the re-PPV group versus 81.8% of the re-PPV+SB group (p=0.047). Although preoperative BCVA was worse in the re-PPV+SB group (p=0.005), postoperative BCVA at the last visit was similar in both groups (p=0.065). In the treatment of recurrent RD with grade C PVR, combining the SB procedure with PPV contributes to anatomical and functional outcomes.