Javier Marco Martínez

Prof. Dr. Javier Marco Martínez


Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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13 July 2020 in Annals of Surgical Oncology
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MGMaría Galán-Olleros
María Galán-Olleros
JMJavier Marco Martínez
Javier Marco Martínez
DODavid Oteo
David Oteo
RCRafael Cristóbal-Bilbao
Rafael Cristóbal-Bilbao
EMElena Manrique
Elena Manrique
JCJuan Luis Cebrian
Juan Luis Cebrian

Verified
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JMJavier Marco Martínez
Javier Marco Martínez
JBJ. Luis Bernal
J. Luis Bernal
CPCristina Fernandez Perez
Cristina Fernandez Perez
FEFrancisco Javier Elola
Francisco Javier Elola
JAJavier Azaña-Gómez
Javier Azaña-Gómez
MMManuel Méndez-Bailón
Manuel Méndez-Bailón
Background: Femoral neck fracture (FNF) is a common condition with a rising incidence, partly due to aging of the population. It is recommended that FNF should be treated at the earliest opportunity, during daytime hours, including weekends. However, early surgery shortens the available time for preoperative medical examination. Cardiac evaluation is critical for good surgical outcomes as most of these patients are older and frail with other comorbid conditions, such as heart failure. The aim of this study was to determine the impact of heart failure on in-hospital outcomes after surgical femoral neck fracture treatment. Methods: We performed a retrospective study using the Spanish National Hospital Discharge Database, 2007–2015. We included patients older than 64 years treated for reduction and internal fixation of FNF. Demographic characteristics of patients, as well as administrative variables, related to patient’s diseases and procedures performed during the episode were evaluated. Results: A total of 234,159 episodes with FNF reduction and internal fixation were identified from Spanish National Health System hospitals during the study period; 986 (0.42%) episodes were excluded, resulting in a final study population of 233,173 episodes. Mean age was 83.7 (±7) years and 179,949 (77.2%) were women (p < 0.001). In the sample, 13,417 (5.8%) episodes had a main or secondary diagnosis of heart failure (HF) (p < 0.001). HF patients had a mean age of 86.1 (±6.3) years, significantly older than the rest (p < 0.001). All the major complications studied showed a higher incidence in patients with HF (p < 0.001). Unadjusted in-hospital mortality was 4.1%, which was significantly higher in patients with HF (18.2%) compared to those without HF (3.3%) (p < 0.001). The average length of stay (LOS) was 11.9 (±9.1) and was also significantly higher in the group with HF (16.5 ± 13.1 vs. 11.6 ± 8.7; p < 0.001). Conclusions: Patients with HF undergoing FNF surgery have longer length of stay and higher rates of both major complications and mortality than those without HF. Although their average length of stay has decreased in the last few years, their mortality rate has remained unchanged.

16 April 2021 in Journal of Clinical Medicine
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JMJavier Marco Martínez
Javier Marco Martínez
FEFrancisco Javier Elola
Francisco Javier Elola
CPCristina Fernandez Perez
Cristina Fernandez Perez
JBJ. Luis Bernal
J. Luis Bernal
FAFrancisco Javier Azaña-Gómez
Francisco Javier Azaña-Gómez
MMManuel Méndez-Bailón
Manuel Méndez-Bailón
Background: The incidence of cholecystectomy is increasing as the result of the aging worldwide. Our aim was to determine the influence of heart failure on in-hospital outcomes in patients undergoing cholecystectomy in the Spanish National Health System (SNHS). Methods: We conducted a retrospective study using the Spanish National Hospital Discharge Database. Patients older than 17 years undergoing cholecystectomy in the period 2007–2015 were included. Demographic and administrative variables related to patients’ diseases as well as procedures were collected. Results: 478,111 episodes of cholecystectomy were identified according to the data from SNHS hospitals in the period evaluated. From all the episodes, 3357 (0.7%) were excluded, as the result the sample was represented by 474,754 episodes. Mean age was 58.3 (+16.5) years, and 287,734 (60.5%) were women (p < 0.001). A primary or secondary diagnosis of HF was identified in 4244 (0.89%) (p < 0.001) and mean age was 76.5 (+9.6) years. A higher incidence of all main complications studied was observed in the HF group (p < 0.001), except stroke (p = 0.753). Unadjusted in-hospital mortality was 1.1%, 12.9% in the group with HF versus 1% in the non HF group (p < 0.001). Average length of hospital stay was 5.4 (+8.9) days, and was higher in patients with HF (16.2 + 17.7 vs. 5.3 + 8.8; p < 0.001). Risk-adjusted in-hospital mortality models’ discrimination was high in both cases, with AUROC values = 0.963 (0.960–0.965) in the APRG-DRG model and AUROC = 0.965 (0.962–0.968) in the CMS adapted model. Median odds ratio (MOR) was high (1.538 and 1.533, respectively), stating an important variability of risk-adjusted outcomes among hospitals. Conclusions: The presence of HF during admission increases in hospital mortality and lengthens the hospital stay in patients undergoing cholecystectomy. However, mortality and hospital stay have significantly decreased during the study period in both groups (HF and non HF patients).

24 February 2024 in Journal of Clinical Medicine
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MFMariam Farid-Zahran
Mariam Farid-Zahran
Manuel Méndez BailonManuel Méndez Bailon
Manuel Méndez Bailon
JPJosé María Pedrajas
José María Pedrajas
RARubén Alonso-Beato
Rubén Alonso-Beato
FGFrancisco Galeano-Valle
Francisco Galeano-Valle
Pablo Demelo‐RodríguezPablo Demelo‐Rodríguez
Pablo Demelo‐Rodríguez
Introduction: Patients with heart failure (HF) are known to have an increased risk of pulmonary embolism (PE), but there is limited evidence regarding the prognostic implications of HF in patients with acute PE and the relationship between PE prognosis and left ventricular ejection fraction (LVEF). The primary objective of this study was the development of a composite outcome (mortality, major bleeding, and recurrence) within the first 30 days. The secondary objective was to identify the role of LVEF in predicting the development of early complications in patients with both HF and reduced LVEF. Material and Methods: A prospective study was conducted at two tertiary hospitals between January 2012 and December 2022 to assess differences among patients diagnosed with acute PE based on the presence or absence of a history of HF. Cox regression models were employed to assess the impact of HF and reduced LVEF on the composite outcome at 30 days. Results: Out of 1991 patients with acute symptomatic PE, 7.13% had a history of HF. Patients with HF were older and had more comorbidities. The HF group exhibited higher mortality (11.27% vs. 4.33%, p < 0.001) and a higher incidence of major bleeding (9.86% vs. 4.54%, p = 0.005). In the multivariate analysis, HF was an independent risk factor for the development of the composite outcome (HR 1.93; 95% CI 1.35–2.76). Reduced LVEF was independently associated with a higher risk of major bleeding (HR 3.44; 95% CI 1.34–8.81). Conclusion: In patients with acute pulmonary embolism, heart failure is independently associated with a higher risk of early complications. Additionally, heart failure with reduced LVEF is an independent risk factor for major bleeding.

1 November 2019 in Revista Clínica Española
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JMJavier Marco Martínez
Javier Marco Martínez
MMM. Méndez
M. Méndez
ACAlfonso J. Cruz-Jentoft
Alfonso J. Cruz-Jentoft
JKJ.L. García Klepzig
J.L. García Klepzig
ECE. Calvo
E. Calvo
RBR. Barba
R. Barba

1 November 2016 in Revista Clínica Española
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Journal Article
Closed access
JMJavier Marco Martínez
Javier Marco Martínez
ERE. Montero Ruíz
E. Montero Ruíz
CPCristina Fernandez Perez
Cristina Fernandez Perez
MBM. Méndez Bailón
M. Méndez Bailón
JKJ.L. García Klepzig
J.L. García Klepzig
FVF. Garrachón Vallo
F. Garrachón Vallo