Dr. Jian Ruan is a Chief Physician and Investigator at the First Affiliated Hospital, Zhejiang University School of Medicine. He earned his PhD in Oncology from Southern Medical University and trained at Nanfang Hospital, advancing from Resident to Associate Chief Physician. In 2019, he joined his current institution, becoming Chief Physician by 2022. His research is dedicated to advancing precision medicine and conversion therapy for liver cancer. His most impactful works include: “Molecular Subgroups of Intrahepatic Cholangiocarcinoma Discovered by Single-Cell RNA Sequencing-Assisted Multiomics Analysis” in CANCER IMMUNOLOGY RESEARCH; “Multiple-omics analysis reveals a dedifferentiation-immune loop in intrahepatic cholangiocarcinoma” in Molecular Therapy; “Induction of Tumor Ferroptosis-Dependent Immunity via an Injectable Attractive Pickering Emulsion Gel” in ADVANCED MATERIALS. Dr. Ruan holds several key leadership roles, including Council Member of the First Youth Council of the China Anti-Cancer Association and Standing Committee Member of its International Exchange Committee. He is also actively involved in numerous specialized committees within Zhejiang Province. His contributions have been recognized with several esteemed honors, including the "Zhejiang Provincial Health Innovative Talent," and "Guangdong Outstanding Young Medical Talent," awards. As Guest Editor, he is committed to highlighting pioneering research that bridges the laboratory and the clinic.