I am the fifth year PhD student in the lab of Dr. Ken Taylor at Institute of Molecular Biophysics in Florida State University. Our lab mainly works on the insect flight muscle structure at sub-nanometer resolution using cryo-EM, and my research focus is thick filament structure of Bombus flight muscle. With the Titan Krios and K3 camera equipped in the institute and single-particle processing, a high-resolution map can be resolved to examine the structure of myosin coiled coils, myosin heads and non-myosin proteins, the correlation of them determines the muscle contraction mechanism.